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Project measure / variable:   Brown2   fall_ave_d5

ID, description, units MPD:22565   fall_ave_d5   latency to fall from accelerating rotarod (8 rpm/min)   [s]  day5  
Data set, strains Brown2   inbred   12 strains     sex: both     age: 10-18wks
Procedure rotarod
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  STRAIN COMPARISON PLOT
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Brown2 - latency to fall from accelerating rotarod (8 rpm/min) day5



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested12 strains12 strains
Mean of the strain means166   s 140   s
Median of the strain means141   s 124   s
SD of the strain means± 75.0 ± 57.8
Coefficient of variation (CV)0.452 0.413
Min–max range of strain means78.7   –   307   s 74.0   –   240   s
Mean sample size per strain12.0   mice 11.7   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 42755.7867 42755.7867 18.7649 < 0.0001
strain 11 1132158.9945 102923.545 45.1715 < 0.0001
sex:strain 11 104504.1834 9500.3803 4.1696 < 0.0001
Residuals 271 617474.5698 2278.5039


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 234.0 80.5   12 23.2 0.343 114.0, 360.0 0.91
129S1/SvImJ m 145.0 43.6   12 12.6 0.301 44.5, 224.0 0.09
A/J f 78.7 26.6   12 7.67 0.338 42.4, 115.0 -1.16
A/J m 83.5 26.4   18 6.22 0.316 46.3, 129.0 -0.97
AKR/J f 224.0 42.7   12 12.3 0.191 150.0, 308.0 0.77
AKR/J m 228.0 58.8   12 17.0 0.258 112.0, 340.0 1.52
BALB/cByJ f 94.3 29.9   21 6.53 0.318 42.2, 158.0 -0.96
BALB/cByJ m 95.6 20.1   12 5.81 0.21 68.9, 128.0 -0.77
BALB/cJ f 83.2 25.7   14 6.88 0.309 34.2, 131.0 -1.1
BALB/cJ m 74.0 28.0   10 8.85 0.378 42.1, 139.0 -1.14
C3H/HeJ f 126.0 30.7   10 9.72 0.244 81.8, 162.0 -0.53
C3H/HeJ m 158.0 88.9   9 29.6 0.564 65.8, 334.0 0.31
C57BL/6J f 249.0 54.9   12 15.9 0.22 165.0, 344.0 1.11
C57BL/6J m 208.0 35.3   12 10.2 0.17 137.0, 239.0 1.18
DBA/2J f 119.0 28.2   12 8.15 0.237 77.4, 181.0 -0.63
DBA/2J m 107.0 39.8   12 11.5 0.373 30.7, 168.0 -0.57
FVB/NJ f 118.0 45.9   12 13.2 0.388 53.9, 194.0 -0.64
FVB/NJ m 94.3 28.5   12 8.23 0.302 48.0, 136.0 -0.79
MOLF/EiJ f 307.0 68.2   12 19.7 0.222 133.0, 360.0 1.88
MOLF/EiJ m 240.0 64.9   11 19.6 0.27 137.0, 344.0 1.73
SJL/J f 202.0 42.3   12 12.2 0.209 128.0, 283.0 0.48
SJL/J m 103.0 24.0   12 6.92 0.233 79.1, 169.0 -0.64
SM/J f 156.0 77.6   10 24.5 0.497 32.1, 293.0 -0.13
SM/J m 142.0 73.4   12 21.2 0.519 65.6, 294.0 0.04


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 234.25 13.7795 261.3785 207.1215
129S1/SvImJ m 144.7917 13.7795 171.9202 117.6631
A/J f 78.7333 13.7795 105.8619 51.6048
A/J m 83.5222 11.2509 105.6726 61.3719
AKR/J f 224.0 13.7795 251.1285 196.8715
AKR/J m 227.6667 13.7795 254.7952 200.5381
BALB/cByJ f 94.2857 10.4163 114.793 73.7785
BALB/cByJ m 95.575 13.7795 122.7035 68.4465
BALB/cJ f 83.1929 12.7574 108.309 58.0767
BALB/cJ m 73.97 15.0947 103.6878 44.2522
C3H/HeJ f 125.76 15.0947 155.4778 96.0422
C3H/HeJ m 157.6556 15.9112 188.9809 126.3302
C57BL/6J f 249.4167 13.7795 276.5452 222.2881
C57BL/6J m 207.75 13.7795 234.8785 180.6215
DBA/2J f 119.1417 13.7795 146.2702 92.0131
DBA/2J m 106.9083 13.7795 134.0369 79.7798
FVB/NJ f 118.075 13.7795 145.2035 90.9465
FVB/NJ m 94.325 13.7795 121.4535 67.1965
MOLF/EiJ f 307.3333 13.7795 334.4619 280.2048
MOLF/EiJ m 240.0 14.3922 268.3348 211.6652
SJL/J f 201.8333 13.7795 228.9619 174.7048
SJL/J m 102.9417 13.7795 130.0702 75.8131
SM/J f 156.11 15.0947 185.8278 126.3922
SM/J m 141.5 13.7795 168.6285 114.3715


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 189.5208 9.7436 208.7036 170.3381
A/J both 81.1278 8.8946 98.6392 63.6164
AKR/J both 225.8333 9.7436 245.0161 206.6506
BALB/cByJ both 94.9304 8.6368 111.9341 77.9267
BALB/cJ both 78.5814 9.8818 98.0363 59.1266
C3H/HeJ both 141.7078 10.9661 163.2973 120.1183
C57BL/6J both 228.5833 9.7436 247.7661 209.4006
DBA/2J both 113.025 9.7436 132.2078 93.8422
FVB/NJ both 106.2 9.7436 125.3828 87.0172
MOLF/EiJ both 273.6667 9.9626 293.2806 254.0528
SJL/J both 152.3875 9.7436 171.5703 133.2047
SM/J both 148.805 10.2192 168.9241 128.6859




  GWAS USING LINEAR MIXED MODELS