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Project measure / variable:   Lake2   corneal_reflex

ID, description, units MPD:21733   corneal_reflex   eye-blink response to corneal stimulation on horizontal wire-grid (score 0-2)   [score]  
Data set, strains Lake2   B6.A consomic w/par   23 strains     sex: both     age: 8wks
Procedure observation (SHIRPA)
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  STRAIN COMPARISON PLOT
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Lake2 - eye-blink response to corneal stimulation on horizontal wire-grid (score 0-2)



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested23 strains23 strains
Mean of the strain means1.08   score 1.03   score
Median of the strain means1.00   score 1.00   score
SD of the strain means± 0.222 ± 0.106
Coefficient of variation (CV)0.205 0.103
Min–max range of strain means1.00   –   2.00   score 1.00   –   1.50   score
Mean sample size per strain8.3   mice 8.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.3997 0.3997 11.277 0.0009
strain 22 9.4573 0.4299 12.1271 < 0.0001
sex:strain 22 1.8795 0.0854 2.4101 0.0005
Residuals 335 11.875 0.0354


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
A/J f 1.38 0.619   16 0.155 0.45 1.35
A/J m 1.0 0.0   8 0.0 0.0 1.0, 1.0 -0.25
B6.A-Chr1 f 1.0 0.0   8 0.0 0.0 1.0, 1.0 -0.37
B6.A-Chr1 m 1.0 0.0   8 0.0 0.0 1.0, 1.0 -0.25
B6.A-Chr10 f 1.0 0.0   8 0.0 0.0 1.0, 1.0 -0.37
B6.A-Chr10 m 1.0 0.0   8 0.0 0.0 1.0, 1.0 -0.25
B6.A-Chr11 f 1.25 0.463   8 0.164 0.37 1.0, 2.0 0.76
B6.A-Chr11 m 1.0 0.0   10 0.0 0.0 1.0, 1.0 -0.25
B6.A-Chr12 f 1.0 0.0   8 0.0 0.0 1.0, 1.0 -0.37
B6.A-Chr12 m 1.0 0.0   8 0.0 0.0 1.0, 1.0 -0.25
B6.A-Chr13 f 1.0 0.0   5 0.0 0.0 1.0, 1.0 -0.37
B6.A-Chr13 m 1.0 0.0   7 0.0 0.0 1.0, 1.0 -0.25
B6.A-Chr14 f 2.0 0.0   8 0.0 0.0 2.0, 2.0 4.14
B6.A-Chr14 m 1.5 0.535   8 0.189 0.356 1.0, 2.0 4.46
B6.A-Chr15 f 1.0 0.0   8 0.0 0.0 1.0, 1.0 -0.37
B6.A-Chr15 m 1.0 0.0   8 0.0 0.0 1.0, 1.0 -0.25
B6.A-Chr16 f 1.0 0.0   8 0.0 0.0 1.0, 1.0 -0.37
B6.A-Chr16 m 1.0 0.0   8 0.0 0.0 1.0, 1.0 -0.25
B6.A-Chr17 f 1.0 0.0   8 0.0 0.0 1.0, 1.0 -0.37
B6.A-Chr17 m 1.0 0.0   8 0.0 0.0 1.0, 1.0 -0.25
B6.A-Chr18 f 1.0 0.0   8 0.0 0.0 1.0, 1.0 -0.37
B6.A-Chr18 m 1.0 0.0   8 0.0 0.0 1.0, 1.0 -0.25
B6.A-Chr19 f 1.0 0.0   8 0.0 0.0 1.0, 1.0 -0.37
B6.A-Chr19 m 1.0 0.0   8 0.0 0.0 1.0, 1.0 -0.25
B6.A-Chr2 f 1.0 0.0   8 0.0 0.0 1.0, 1.0 -0.37
B6.A-Chr2 m 1.0 0.0   8 0.0 0.0 1.0, 1.0 -0.25
B6.A-Chr3 f 1.12 0.354   8 0.125 0.314 1.0, 2.0 0.17
B6.A-Chr3 m 1.0 0.0   8 0.0 0.0 1.0, 1.0 -0.25
B6.A-Chr4 f 1.0 0.0   7 0.0 0.0 1.0, 1.0 -0.37
B6.A-Chr4 m 1.0 0.0   8 0.0 0.0 1.0, 1.0 -0.25
B6.A-Chr5 f 1.0 0.0   8 0.0 0.0 1.0, 1.0 -0.37
B6.A-Chr5 m 1.0 0.0   8 0.0 0.0 1.0, 1.0 -0.25
B6.A-Chr6 f 1.0 0.0   8 0.0 0.0 1.0, 1.0 -0.37
B6.A-Chr6 m 1.12 0.354   8 0.125 0.314 1.0, 2.0 0.88
B6.A-Chr7 f 1.0 0.0   8 0.0 0.0 1.0, 1.0 -0.37
B6.A-Chr7 m 1.0 0.0   8 0.0 0.0 1.0, 1.0 -0.25
B6.A-Chr8 f 1.12 0.354   8 0.125 0.314 1.0, 2.0 0.17
B6.A-Chr8 m 1.0 0.0   8 0.0 0.0 1.0, 1.0 -0.25
B6.A-Chr9 f 1.0 0.0   8 0.0 0.0 1.0, 1.0 -0.37
B6.A-Chr9 m 1.0 0.0   8 0.0 0.0 1.0, 1.0 -0.25
B6.A-ChrX f 1.0 0.0   8 0.0 0.0 1.0, 1.0 -0.37
B6.A-ChrX m 1.0 0.0   8 0.0 0.0 1.0, 1.0 -0.25
B6.A-ChrY f 1.0 0.0   8 0.0 0.0 1.0, 1.0 -0.37
B6.A-ChrY m 1.0 0.0   8 0.0 0.0 1.0, 1.0 -0.25
C57BL/6J f 1.0 0.0   16 0.0 0.0 1.0, 1.0 -0.37
C57BL/6J m 1.0 0.0   8 0.0 0.0 1.0, 1.0 -0.25


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J f 1.375 0.0471 1.4676 1.2824
A/J m 1.0 0.0666 1.1309 0.8691
B6.A-Chr1 f 1.0 0.0666 1.1309 0.8691
B6.A-Chr1 m 1.0 0.0666 1.1309 0.8691
B6.A-Chr10 f 1.0 0.0666 1.1309 0.8691
B6.A-Chr10 m 1.0 0.0666 1.1309 0.8691
B6.A-Chr11 f 1.25 0.0666 1.3809 1.1191
B6.A-Chr11 m 1.0 0.0595 1.1171 0.8829
B6.A-Chr12 f 1.0 0.0666 1.1309 0.8691
B6.A-Chr12 m 1.0 0.0666 1.1309 0.8691
B6.A-Chr13 f 1.0 0.0842 1.1656 0.8344
B6.A-Chr13 m 1.0 0.0712 1.14 0.86
B6.A-Chr14 f 2.0 0.0666 2.1309 1.8691
B6.A-Chr14 m 1.5 0.0666 1.6309 1.3691
B6.A-Chr15 f 1.0 0.0666 1.1309 0.8691
B6.A-Chr15 m 1.0 0.0666 1.1309 0.8691
B6.A-Chr16 f 1.0 0.0666 1.1309 0.8691
B6.A-Chr16 m 1.0 0.0666 1.1309 0.8691
B6.A-Chr17 f 1.0 0.0666 1.1309 0.8691
B6.A-Chr17 m 1.0 0.0666 1.1309 0.8691
B6.A-Chr18 f 1.0 0.0666 1.1309 0.8691
B6.A-Chr18 m 1.0 0.0666 1.1309 0.8691
B6.A-Chr19 f 1.0 0.0666 1.1309 0.8691
B6.A-Chr19 m 1.0 0.0666 1.1309 0.8691
B6.A-Chr2 f 1.0 0.0666 1.1309 0.8691
B6.A-Chr2 m 1.0 0.0666 1.1309 0.8691
B6.A-Chr3 f 1.125 0.0666 1.2559 0.9941
B6.A-Chr3 m 1.0 0.0666 1.1309 0.8691
B6.A-Chr4 f 1.0 0.0712 1.14 0.86
B6.A-Chr4 m 1.0 0.0666 1.1309 0.8691
B6.A-Chr5 f 1.0 0.0666 1.1309 0.8691
B6.A-Chr5 m 1.0 0.0666 1.1309 0.8691
B6.A-Chr6 f 1.0 0.0666 1.1309 0.8691
B6.A-Chr6 m 1.125 0.0666 1.2559 0.9941
B6.A-Chr7 f 1.0 0.0666 1.1309 0.8691
B6.A-Chr7 m 1.0 0.0666 1.1309 0.8691
B6.A-Chr8 f 1.125 0.0666 1.2559 0.9941
B6.A-Chr8 m 1.0 0.0666 1.1309 0.8691
B6.A-Chr9 f 1.0 0.0666 1.1309 0.8691
B6.A-Chr9 m 1.0 0.0666 1.1309 0.8691
B6.A-ChrX f 1.0 0.0666 1.1309 0.8691
B6.A-ChrX m 1.0 0.0666 1.1309 0.8691
B6.A-ChrY f 1.0 0.0666 1.1309 0.8691
B6.A-ChrY m 1.0 0.0666 1.1309 0.8691
C57BL/6J f 1.0 0.0471 1.0926 0.9074
C57BL/6J m 1.0 0.0666 1.1309 0.8691


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
A/J both 1.1875 0.0408 1.2677 1.1073
B6.A-Chr1 both 1.0 0.0471 1.0926 0.9074
B6.A-Chr10 both 1.0 0.0471 1.0926 0.9074
B6.A-Chr11 both 1.125 0.0447 1.2128 1.0372
B6.A-Chr12 both 1.0 0.0471 1.0926 0.9074
B6.A-Chr13 both 1.0 0.0551 1.1084 0.8916
B6.A-Chr14 both 1.75 0.0471 1.8426 1.6574
B6.A-Chr15 both 1.0 0.0471 1.0926 0.9074
B6.A-Chr16 both 1.0 0.0471 1.0926 0.9074
B6.A-Chr17 both 1.0 0.0471 1.0926 0.9074
B6.A-Chr18 both 1.0 0.0471 1.0926 0.9074
B6.A-Chr19 both 1.0 0.0471 1.0926 0.9074
B6.A-Chr2 both 1.0 0.0471 1.0926 0.9074
B6.A-Chr3 both 1.0625 0.0471 1.1551 0.9699
B6.A-Chr4 both 1.0 0.0487 1.0958 0.9042
B6.A-Chr5 both 1.0 0.0471 1.0926 0.9074
B6.A-Chr6 both 1.0625 0.0471 1.1551 0.9699
B6.A-Chr7 both 1.0 0.0471 1.0926 0.9074
B6.A-Chr8 both 1.0625 0.0471 1.1551 0.9699
B6.A-Chr9 both 1.0 0.0471 1.0926 0.9074
B6.A-ChrX both 1.0 0.0471 1.0926 0.9074
B6.A-ChrY both 1.0 0.0471 1.0926 0.9074
C57BL/6J both 1.0 0.0408 1.0802 0.9198




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA