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Project measure / variable:   Lake2   limb_tone

ID, description, units MPD:21716   limb_tone   resistance to gentle finger-tip pressure of the hind paws during supine restraint (score 0-4)   [score]  
Data set, strains Lake2   B6.A consomic w/par   23 strains     sex: both     age: 8wks
Procedure observation (SHIRPA)
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  STRAIN COMPARISON PLOT
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Lake2 - resistance to gentle finger-tip pressure of the hind paws during supine restraint (score 0-4)



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested23 strains23 strains
Mean of the strain means1.00   score 1.09   score
Median of the strain means1.00   score 1.00   score
SD of the strain means± 0 ± 0.288
Coefficient of variation (CV)0 0.265
Min–max range of strain means1.00   –   1.00   score 1.00   –   2.00   score
Mean sample size per strain7.7   mice 7.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.7335 0.7335 3.14698700228149e+28 < 0.0001
strain 22 7.2753 0.3307 1.418781005315e+28 < 0.0001
sex:strain 22 7.2534 0.3297 1.4145201866695e+28 < 0.0001
Residuals 301 0.0 0.0


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
A/J f 1.0 0.0   8 0.0 0.0 1.0, 1.0 0.0
A/J m 2.0 0.0   8 0.0 0.0 2.0, 2.0 3.17
B6.A-Chr1 f 1.0 0.0   4 0.0 0.0 1.0, 1.0 0.0
B6.A-Chr1 m 1.0 0.0   8 0.0 0.0 1.0, 1.0 -0.3
B6.A-Chr10 f 1.0 0.0   8 0.0 0.0 1.0, 1.0 0.0
B6.A-Chr10 m 1.0 0.0   8 0.0 0.0 1.0, 1.0 -0.3
B6.A-Chr11 f 1.0 0.0   8 0.0 0.0 1.0, 1.0 0.0
B6.A-Chr11 m 1.0 0.0   10 0.0 0.0 1.0, 1.0 -0.3
B6.A-Chr12 f 1.0 0.0   8 0.0 0.0 1.0, 1.0 0.0
B6.A-Chr12 m 1.0 0.0   8 0.0 0.0 1.0, 1.0 -0.3
B6.A-Chr13 f 1.0 0.0   5 0.0 0.0 1.0, 1.0 0.0
B6.A-Chr13 m 1.0 0.0   7 0.0 0.0 1.0, 1.0 -0.3
B6.A-Chr14 f 1.0 0.0   8 0.0 0.0 1.0, 1.0 0.0
B6.A-Chr14 m 1.0 0.0   8 0.0 0.0 1.0, 1.0 -0.3
B6.A-Chr15 f 1.0 0.0   8 0.0 0.0 1.0, 1.0 0.0
B6.A-Chr15 m 1.0 0.0   8 0.0 0.0 1.0, 1.0 -0.3
B6.A-Chr16 f 1.0 0.0   8 0.0 0.0 1.0, 1.0 0.0
B6.A-Chr16 m 1.0 0.0   4 0.0 0.0 1.0, 1.0 -0.3
B6.A-Chr17 f 1.0 0.0   8 0.0 0.0 1.0, 1.0 0.0
B6.A-Chr17 m 1.0 0.0   8 0.0 0.0 1.0, 1.0 -0.3
B6.A-Chr18 f 1.0 0.0   8 0.0 0.0 1.0, 1.0 0.0
B6.A-Chr18 m 1.0 0.0   8 0.0 0.0 1.0, 1.0 -0.3
B6.A-Chr19 f 1.0 0.0   8 0.0 0.0 1.0, 1.0 0.0
B6.A-Chr19 m 1.0 0.0   8 0.0 0.0 1.0, 1.0 -0.3
B6.A-Chr2 f 1.0 0.0   5 0.0 0.0 1.0, 1.0 0.0
B6.A-Chr2 m 1.0 0.0   4 0.0 0.0 1.0, 1.0 -0.3
B6.A-Chr3 f 1.0 0.0   8 0.0 0.0 1.0, 1.0 0.0
B6.A-Chr3 m 1.0 0.0   8 0.0 0.0 1.0, 1.0 -0.3
B6.A-Chr4 f 1.0 0.0   7 0.0 0.0 1.0, 1.0 0.0
B6.A-Chr4 m 1.0 0.0   8 0.0 0.0 1.0, 1.0 -0.3
B6.A-Chr5 f 1.0 0.0   8 0.0 0.0 1.0, 1.0 0.0
B6.A-Chr5 m 1.0 0.0   8 0.0 0.0 1.0, 1.0 -0.3
B6.A-Chr6 f 1.0 0.0   8 0.0 0.0 1.0, 1.0 0.0
B6.A-Chr6 m 1.0 0.0   8 0.0 0.0 1.0, 1.0 -0.3
B6.A-Chr7 f 1.0 0.0   8 0.0 0.0 1.0, 1.0 0.0
B6.A-Chr7 m 1.0 0.0   8 0.0 0.0 1.0, 1.0 -0.3
B6.A-Chr8 f 1.0 0.0   8 0.0 0.0 1.0, 1.0 0.0
B6.A-Chr8 m 1.0 0.0   5 0.0 0.0 1.0, 1.0 -0.3
B6.A-Chr9 f 1.0 0.0   8 0.0 0.0 1.0, 1.0 0.0
B6.A-Chr9 m 1.0 0.0   8 0.0 0.0 1.0, 1.0 -0.3
B6.A-ChrX f 1.0 0.0   8 0.0 0.0 1.0, 1.0 0.0
B6.A-ChrX m 1.0 0.0   8 0.0 0.0 1.0, 1.0 -0.3
B6.A-ChrY f 1.0 0.0   8 0.0 0.0 1.0, 1.0 0.0
B6.A-ChrY m 1.0 0.0   8 0.0 0.0 1.0, 1.0 -0.3
C57BL/6J f 1.0 0.0   8 0.0 0.0 1.0, 1.0 0.0
C57BL/6J m 2.0 0.0   8 0.0 0.0 2.0, 2.0 3.17


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J f 1.0 0.0 1.0 1.0
A/J m 2.0 0.0 2.0 2.0
B6.A-Chr1 f 1.0 0.0 1.0 1.0
B6.A-Chr1 m 1.0 0.0 1.0 1.0
B6.A-Chr10 f 1.0 0.0 1.0 1.0
B6.A-Chr10 m 1.0 0.0 1.0 1.0
B6.A-Chr11 f 1.0 0.0 1.0 1.0
B6.A-Chr11 m 1.0 0.0 1.0 1.0
B6.A-Chr12 f 1.0 0.0 1.0 1.0
B6.A-Chr12 m 1.0 0.0 1.0 1.0
B6.A-Chr13 f 1.0 0.0 1.0 1.0
B6.A-Chr13 m 1.0 0.0 1.0 1.0
B6.A-Chr14 f 1.0 0.0 1.0 1.0
B6.A-Chr14 m 1.0 0.0 1.0 1.0
B6.A-Chr15 f 1.0 0.0 1.0 1.0
B6.A-Chr15 m 1.0 0.0 1.0 1.0
B6.A-Chr16 f 1.0 0.0 1.0 1.0
B6.A-Chr16 m 1.0 0.0 1.0 1.0
B6.A-Chr17 f 1.0 0.0 1.0 1.0
B6.A-Chr17 m 1.0 0.0 1.0 1.0
B6.A-Chr18 f 1.0 0.0 1.0 1.0
B6.A-Chr18 m 1.0 0.0 1.0 1.0
B6.A-Chr19 f 1.0 0.0 1.0 1.0
B6.A-Chr19 m 1.0 0.0 1.0 1.0
B6.A-Chr2 f 1.0 0.0 1.0 1.0
B6.A-Chr2 m 1.0 0.0 1.0 1.0
B6.A-Chr3 f 1.0 0.0 1.0 1.0
B6.A-Chr3 m 1.0 0.0 1.0 1.0
B6.A-Chr4 f 1.0 0.0 1.0 1.0
B6.A-Chr4 m 1.0 0.0 1.0 1.0
B6.A-Chr5 f 1.0 0.0 1.0 1.0
B6.A-Chr5 m 1.0 0.0 1.0 1.0
B6.A-Chr6 f 1.0 0.0 1.0 1.0
B6.A-Chr6 m 1.0 0.0 1.0 1.0
B6.A-Chr7 f 1.0 0.0 1.0 1.0
B6.A-Chr7 m 1.0 0.0 1.0 1.0
B6.A-Chr8 f 1.0 0.0 1.0 1.0
B6.A-Chr8 m 1.0 0.0 1.0 1.0
B6.A-Chr9 f 1.0 0.0 1.0 1.0
B6.A-Chr9 m 1.0 0.0 1.0 1.0
B6.A-ChrX f 1.0 0.0 1.0 1.0
B6.A-ChrX m 1.0 0.0 1.0 1.0
B6.A-ChrY f 1.0 0.0 1.0 1.0
B6.A-ChrY m 1.0 0.0 1.0 1.0
C57BL/6J f 1.0 0.0 1.0 1.0
C57BL/6J m 2.0 0.0 2.0 2.0


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
A/J both 1.5 0.0 1.5 1.5
B6.A-Chr1 both 1.0 0.0 1.0 1.0
B6.A-Chr10 both 1.0 0.0 1.0 1.0
B6.A-Chr11 both 1.0 0.0 1.0 1.0
B6.A-Chr12 both 1.0 0.0 1.0 1.0
B6.A-Chr13 both 1.0 0.0 1.0 1.0
B6.A-Chr14 both 1.0 0.0 1.0 1.0
B6.A-Chr15 both 1.0 0.0 1.0 1.0
B6.A-Chr16 both 1.0 0.0 1.0 1.0
B6.A-Chr17 both 1.0 0.0 1.0 1.0
B6.A-Chr18 both 1.0 0.0 1.0 1.0
B6.A-Chr19 both 1.0 0.0 1.0 1.0
B6.A-Chr2 both 1.0 0.0 1.0 1.0
B6.A-Chr3 both 1.0 0.0 1.0 1.0
B6.A-Chr4 both 1.0 0.0 1.0 1.0
B6.A-Chr5 both 1.0 0.0 1.0 1.0
B6.A-Chr6 both 1.0 0.0 1.0 1.0
B6.A-Chr7 both 1.0 0.0 1.0 1.0
B6.A-Chr8 both 1.0 0.0 1.0 1.0
B6.A-Chr9 both 1.0 0.0 1.0 1.0
B6.A-ChrX both 1.0 0.0 1.0 1.0
B6.A-ChrY both 1.0 0.0 1.0 1.0
C57BL/6J both 1.5 0.0 1.5 1.5




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA