Project measure / variable:   Lake1   RR

ID, description, units MPD:19948   RR   interval between R-waves (RR)   [ms]  
Data set, strains Lake1   B6.A consomic w/par   23 strains     sex: both     age: 11wks
Procedure ECG
Ontology mappings

  STRAIN COMPARISON PLOT
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Lake1 - interval between R-waves (RR)



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested23 strains23 strains
Mean of the strain means82.5   ms 80.5   ms
Median of the strain means81.4   ms 80.4   ms
SD of the strain means± 4.19 ± 1.88
Coefficient of variation (CV)0.0509 0.0233
Min–max range of strain means78.6   –   98.1   ms 76.5   –   85.4   ms
Mean sample size per strain8.0   mice 7.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 365.7978 365.7978 11.2697 0.0009
strain 22 2625.7765 119.3535 3.6771 < 0.0001
sex:strain 22 1105.2055 50.2366 1.5477 0.057
Residuals 323 10484.0871 32.4585


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
A/J f 98.1 12.3   8 4.36 0.126 86.8, 123.0 3.73
A/J m 83.1 9.56   8 3.38 0.115 73.3, 102.0 1.39
B6.A-Chr1 f 78.7 1.61   8 0.568 0.0204 76.2, 81.2 -0.9
B6.A-Chr1 m 76.5 2.5   8 0.885 0.0327 72.5, 80.1 -2.12
B6.A-Chr10 f 86.0 10.3   9 3.43 0.12 76.6, 112.0 0.84
B6.A-Chr10 m 85.4 15.2   8 5.38 0.178 74.0, 122.0 2.61
B6.A-Chr11 f 83.4 6.0   8 2.12 0.072 76.4, 94.5 0.22
B6.A-Chr11 m 80.1 4.83   8 1.71 0.0603 74.1, 88.3 -0.21
B6.A-Chr12 f 78.6 1.66   8 0.585 0.021 77.1, 81.8 -0.92
B6.A-Chr12 m 78.1 1.12   8 0.395 0.0143 76.4, 79.5 -1.27
B6.A-Chr13 f 79.4 3.63   8 1.28 0.0458 72.9, 85.0 -0.73
B6.A-Chr13 m 80.3 5.92   8 2.09 0.0736 73.3, 92.6 -0.1
B6.A-Chr14 f 86.0 8.53   8 3.02 0.0992 79.8, 105.0 0.84
B6.A-Chr14 m 81.0 3.56   8 1.26 0.0439 77.5, 86.0 0.27
B6.A-Chr15 f 84.2 5.74   9 1.91 0.0682 77.1, 97.0 0.41
B6.A-Chr15 m 80.6 2.31   7 0.872 0.0286 77.3, 83.3 0.06
B6.A-Chr16 f 82.2 6.98   8 2.47 0.085 77.6, 99.1 -0.06
B6.A-Chr16 m 79.3 3.44   8 1.22 0.0434 75.9, 84.9 -0.63
B6.A-Chr17 f 85.9 6.22   8 2.2 0.0724 80.3, 96.9 0.82
B6.A-Chr17 m 81.5 2.7   7 1.02 0.0331 78.0, 86.0 0.54
B6.A-Chr18 f 81.4 4.64   8 1.64 0.057 74.2, 90.0 -0.25
B6.A-Chr18 m 80.5 2.65   8 0.936 0.0329 75.8, 83.9 0.01
B6.A-Chr19 f 81.3 5.58   8 1.97 0.0686 77.0, 91.6 -0.28
B6.A-Chr19 m 77.9 2.41   8 0.853 0.031 74.4, 80.9 -1.38
B6.A-Chr2 f 81.2 3.47   8 1.23 0.0427 76.9, 86.8 -0.3
B6.A-Chr2 m 79.4 3.8   8 1.35 0.0479 74.6, 86.4 -0.58
B6.A-Chr3 f 79.8 2.4   8 0.848 0.0301 75.7, 82.0 -0.63
B6.A-Chr3 m 83.4 5.82   8 2.06 0.0698 75.1, 92.8 1.55
B6.A-Chr4 f 83.1 6.74   8 2.38 0.0811 77.5, 95.9 0.15
B6.A-Chr4 m 81.4 7.1   8 2.51 0.0872 72.8, 91.8 0.49
B6.A-Chr5 f 83.3 4.26   8 1.51 0.0511 76.9, 88.7 0.2
B6.A-Chr5 m 80.2 3.9   8 1.38 0.0486 77.6, 89.3 -0.15
B6.A-Chr6 f 80.8 4.3   7 1.63 0.0532 77.5, 90.3 -0.4
B6.A-Chr6 m 80.7 5.01   8 1.77 0.0621 76.8, 92.6 0.11
B6.A-Chr7 f 81.9 4.87   8 1.72 0.0595 76.5, 92.2 -0.13
B6.A-Chr7 m 81.8 4.43   8 1.57 0.0541 76.4, 89.9 0.7
B6.A-Chr8 f 84.6 8.54   8 3.02 0.101 77.5, 102.0 0.51
B6.A-Chr8 m 80.8 6.53   12 1.88 0.0808 70.9, 96.9 0.17
B6.A-Chr9 f 79.1 1.34   8 0.473 0.0169 76.7, 80.5 -0.8
B6.A-Chr9 m 79.0 1.38   6 0.562 0.0174 77.1, 80.7 -0.79
B6.A-ChrX f 78.9 2.28   8 0.805 0.0289 75.8, 82.2 -0.85
B6.A-ChrX m 80.4 4.57   8 1.61 0.0568 73.2, 88.6 -0.05
B6.A-ChrY f 79.5 1.52   8 0.538 0.0191 77.5, 81.8 -0.71
B6.A-ChrY m 80.2 4.31   8 1.52 0.0537 75.6, 89.8 -0.15
C57BL/6J f 79.2 1.83   8 0.649 0.0232 76.5, 81.8 -0.78
C57BL/6J m 79.6 3.03   8 1.07 0.0381 76.5, 85.1 -0.47


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J f 98.1 2.0143 102.0628 94.1372
A/J m 83.1375 2.0143 87.1003 79.1747
B6.A-Chr1 f 78.6625 2.0143 82.6253 74.6997
B6.A-Chr1 m 76.525 2.0143 80.4878 72.5622
B6.A-Chr10 f 85.9889 1.8991 89.725 82.2528
B6.A-Chr10 m 85.4125 2.0143 89.3753 81.4497
B6.A-Chr11 f 83.375 2.0143 87.3378 79.4122
B6.A-Chr11 m 80.0625 2.0143 84.0253 76.0997
B6.A-Chr12 f 78.6375 2.0143 82.6003 74.6747
B6.A-Chr12 m 78.1125 2.0143 82.0753 74.1497
B6.A-Chr13 f 79.4 2.0143 83.3628 75.4372
B6.A-Chr13 m 80.35 2.0143 84.3128 76.3872
B6.A-Chr14 f 86.0375 2.0143 90.0003 82.0747
B6.A-Chr14 m 80.9875 2.0143 84.9503 77.0247
B6.A-Chr15 f 84.1778 1.8991 87.9139 80.4417
B6.A-Chr15 m 80.6429 2.1534 84.8792 76.4065
B6.A-Chr16 f 82.1625 2.0143 86.1253 78.1997
B6.A-Chr16 m 79.325 2.0143 83.2878 75.3622
B6.A-Chr17 f 85.9375 2.0143 89.9003 81.9747
B6.A-Chr17 m 81.4571 2.1534 85.6935 77.2208
B6.A-Chr18 f 81.425 2.0143 85.3878 77.4622
B6.A-Chr18 m 80.5375 2.0143 84.5003 76.5747
B6.A-Chr19 f 81.325 2.0143 85.2878 77.3622
B6.A-Chr19 m 77.8625 2.0143 81.8253 73.8997
B6.A-Chr2 f 81.1875 2.0143 85.1503 77.2247
B6.A-Chr2 m 79.4 2.0143 83.3628 75.4372
B6.A-Chr3 f 79.7875 2.0143 83.7503 75.8247
B6.A-Chr3 m 83.4125 2.0143 87.3753 79.4497
B6.A-Chr4 f 83.125 2.0143 87.0878 79.1622
B6.A-Chr4 m 81.4375 2.0143 85.4003 77.4747
B6.A-Chr5 f 83.275 2.0143 87.2378 79.3122
B6.A-Chr5 m 80.2375 2.0143 84.2003 76.2747
B6.A-Chr6 f 80.8429 2.1534 85.0792 76.6065
B6.A-Chr6 m 80.6875 2.0143 84.6503 76.7247
B6.A-Chr7 f 81.9 2.0143 85.8628 77.9372
B6.A-Chr7 m 81.7875 2.0143 85.7503 77.8247
B6.A-Chr8 f 84.6125 2.0143 88.5753 80.6497
B6.A-Chr8 m 80.7583 1.6446 83.9939 77.5228
B6.A-Chr9 f 79.075 2.0143 83.0378 75.1122
B6.A-Chr9 m 79.0333 2.3259 83.6091 74.4575
B6.A-ChrX f 78.875 2.0143 82.8378 74.9122
B6.A-ChrX m 80.35 2.0143 84.3128 76.3872
B6.A-ChrY f 79.5125 2.0143 83.4753 75.5497
B6.A-ChrY m 80.2 2.0143 84.1628 76.2372
C57BL/6J f 79.2 2.0143 83.1628 75.2372
C57BL/6J m 79.6 2.0143 83.5628 75.6372


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
A/J both 90.6187 1.4243 93.4208 87.8167
B6.A-Chr1 both 77.5938 1.4243 80.3958 74.7917
B6.A-Chr10 both 85.7007 1.3842 88.4238 82.9775
B6.A-Chr11 both 81.7187 1.4243 84.5208 78.9167
B6.A-Chr12 both 78.375 1.4243 81.1771 75.5729
B6.A-Chr13 both 79.875 1.4243 82.6771 77.0729
B6.A-Chr14 both 83.5125 1.4243 86.3146 80.7104
B6.A-Chr15 both 82.4103 1.4356 85.2346 79.5861
B6.A-Chr16 both 80.7437 1.4243 83.5458 77.9417
B6.A-Chr17 both 83.6973 1.4743 86.5978 80.7969
B6.A-Chr18 both 80.9812 1.4243 83.7833 78.1792
B6.A-Chr19 both 79.5937 1.4243 82.3958 76.7917
B6.A-Chr2 both 80.2937 1.4243 83.0958 77.4917
B6.A-Chr3 both 81.6 1.4243 84.4021 78.7979
B6.A-Chr4 both 82.2813 1.4243 85.0833 79.4792
B6.A-Chr5 both 81.7563 1.4243 84.5583 78.9542
B6.A-Chr6 both 80.7652 1.4743 83.6656 77.8647
B6.A-Chr7 both 81.8437 1.4243 84.6458 79.0417
B6.A-Chr8 both 82.6854 1.3002 85.2434 80.1275
B6.A-Chr9 both 79.0542 1.5384 82.0808 76.0276
B6.A-ChrX both 79.6125 1.4243 82.4146 76.8104
B6.A-ChrY both 79.8562 1.4243 82.6583 77.0542
C57BL/6J both 79.4 1.4243 82.2021 76.5979




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA