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Project measure / variable:   Paigen4   HDLC

ID, description, units MPD:19701   HDLC   HDL cholesterol (plasma)   [mg/dL]  
Data set, strains Paigen4   inbred w/CC7   43 strains     sex: both     age: 10wks
Procedure lipid profile
Ontology mappings

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  STRAIN COMPARISON PLOT
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Paigen4 - HDL cholesterol (plasma)



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested42 strains43 strains
Mean of the strain means61.4   mg/dL 78.6   mg/dL
Median of the strain means53.5   mg/dL 71.5   mg/dL
SD of the strain means± 23.9 ± 27.5
Coefficient of variation (CV)0.388 0.350
Min–max range of strain means34.0   –   147   mg/dL 22.7   –   143   mg/dL
Mean sample size per strain11.9   mice 12.0   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 74904.5798 74904.5798 399.8877 < 0.0001
strain 41 544381.2344 13277.5911 70.8841 < 0.0001
sex:strain 41 48135.1251 1174.0274 6.2677 < 0.0001
Residuals 935 175138.6121 187.314


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 83.9 11.7   23 2.45 0.14 61.6, 103.0 0.94
129S1/SvImJ m 114.0 12.9   9 4.29 0.113 99.0, 137.0 1.28
A/J f 46.7 9.42   10 2.98 0.202 37.0, 63.0 -0.62
A/J m 51.8 12.0   12 3.47 0.232 30.0, 73.0 -0.98
AKR/J f 59.6 16.4   18 3.87 0.276 33.0, 85.8 -0.08
AKR/J m 65.8 21.5   10 6.81 0.328 29.0, 104.0 -0.47
BALB/cByJ f 55.3 9.0   18 2.12 0.163 39.0, 69.0 -0.26
BALB/cByJ m 80.5 10.3   15 2.66 0.128 65.0, 97.0 0.07
BALB/cJ m 74.6 16.0   5 7.15 0.214 50.0, 94.0 -0.15
BTBR T+ Itpr3tf/J f 64.5 4.39   11 1.32 0.0681 57.0, 71.0 0.13
BTBR T+ Itpr3tf/J m 87.3 4.15   9 1.38 0.0475 83.5, 95.0 0.31
BUB/BnJ f 43.0 9.65   10 3.05 0.224 27.0, 60.0 -0.77
BUB/BnJ m 81.0 13.8   10 4.35 0.17 61.6, 106.0 0.09
C3H/HeJ f 79.1 11.6   9 3.86 0.146 56.2, 91.8 0.74
C3H/HeJ m 107.0 2.05   9 0.683 0.0191 104.0, 110.0 1.03
C57BL/10J f 51.0 6.74   22 1.44 0.132 38.0, 63.8 -0.44
C57BL/10J m 22.7 15.7   9 5.22 0.69 5.8, 54.5 -2.03
C57BL/6J f 37.9 14.6   25 2.91 0.384 10.0, 66.0 -0.99
C57BL/6J m 59.0 26.5   11 7.99 0.449 18.6, 95.0 -0.71
C57BLKS/J f 51.7 4.99   10 1.58 0.0964 45.4, 59.4 -0.41
C57BLKS/J m 64.3 8.74   12 2.52 0.136 50.0, 85.0 -0.52
C57BR/cdJ f 46.8 22.7   9 7.56 0.485 9.28, 69.0 -0.61
C57BR/cdJ m 60.1 29.0   13 8.06 0.483 7.0, 95.0 -0.67
C57L/J f 42.5 7.2   15 1.86 0.17 30.0, 56.0 -0.79
C57L/J m 46.6 19.9   22 4.25 0.428 10.4, 73.1 -1.16
C58/J f 62.2 7.38   10 2.33 0.119 49.0, 72.0 0.03
C58/J m 73.1 17.7   19 4.05 0.242 34.0, 110.0 -0.2
CAST/EiJ f 36.6 3.85   11 1.16 0.105 29.0, 41.0 -1.04
CAST/EiJ m 51.0 5.01   14 1.34 0.0982 42.0, 59.0 -1.0
CBA/J f 64.0 9.29   10 2.94 0.145 52.0, 79.0 0.11
CBA/J m 84.2 5.12   8 1.81 0.0608 77.0, 91.0 0.2
CE/J f 58.9 14.5   11 4.37 0.246 37.0, 78.0 -0.11
CE/J m 66.6 33.5   10 10.6 0.503 10.4, 97.0 -0.44
CZECHII/EiJ f 50.9 6.6   9 2.2 0.13 39.0, 61.0 -0.44
CZECHII/EiJ m 56.6 3.01   11 0.907 0.0531 52.0, 61.0 -0.8
DBA/1J f 47.3 9.0   8 3.18 0.19 33.0, 55.7 -0.59
DBA/1J m 62.4 9.47   15 2.45 0.152 44.0, 82.0 -0.59
DBA/2J f 40.3 9.8   10 3.1 0.243 23.0, 53.0 -0.89
DBA/2J m 75.5 6.08   12 1.76 0.0806 67.0, 86.0 -0.11
FVB/NJ f 98.3 9.59   10 3.03 0.0976 86.0, 117.0 1.55
FVB/NJ m 130.0 12.0   13 3.32 0.0922 105.0, 147.0 1.87
I/LnJ f 34.0 5.94   12 1.71 0.175 24.0, 45.0 -1.15
I/LnJ m 59.0 12.5   13 3.47 0.212 39.0, 82.1 -0.71
JF1/MsJ f 48.8 8.4   8 2.97 0.172 38.9, 61.0 -0.53
JF1/MsJ m 57.9 5.52   11 1.66 0.0954 49.0, 65.0 -0.75
KK/HlJ f 147.0 8.66   9 2.89 0.0588 135.0, 164.0 3.59
KK/HlJ m 137.0 29.2   10 9.23 0.213 69.0, 161.0 2.12
LP/J f 57.8 28.2   16 7.04 0.487 9.0, 87.0 -0.15
LP/J m 71.4 32.7   8 11.5 0.458 12.8, 108.0 -0.26
MA/MyJ f 76.4 7.41   10 2.34 0.0969 64.0, 86.4 0.63
MA/MyJ m 114.0 24.1   11 7.26 0.211 85.0, 153.0 1.28
MOLF/EiJ f 49.2 6.57   13 1.82 0.134 39.0, 59.0 -0.51
MOLF/EiJ m 55.2 9.49   15 2.45 0.172 41.0, 74.0 -0.85
MSM/MsJ f 73.4 15.6   12 4.51 0.213 47.5, 99.4 0.5
MSM/MsJ m 69.9 9.32   12 2.69 0.133 56.2, 85.3 -0.32
NOD/ShiLtJ f 69.2 13.3   10 4.19 0.192 45.4, 95.0 0.33
NOD/ShiLtJ m 86.8 12.7   18 3.0 0.147 64.0, 114.0 0.3
NON/ShiLtJ f 71.6 9.7   10 3.07 0.135 57.0, 90.0 0.43
NON/ShiLtJ m 109.0 20.3   14 5.43 0.186 54.5, 140.0 1.1
NZB/BlNJ f 110.0 15.3   11 4.62 0.139 86.4, 132.0 2.04
NZB/BlNJ m 143.0 20.9   9 6.98 0.147 114.0, 174.0 2.34
NZW/LacJ f 112.0 16.5   6 6.75 0.148 85.0, 131.0 2.12
NZW/LacJ m 118.0 11.9   10 3.77 0.101 99.0, 136.0 1.43
PERA/EiJ f 47.2 7.42   8 2.62 0.157 37.0, 57.0 -0.6
PERA/EiJ m 47.3 10.9   9 3.64 0.231 26.0, 63.0 -1.14
PL/J f 55.8 14.7   23 3.06 0.263 30.0, 89.3 -0.24
PL/J m 85.1 8.79   19 2.02 0.103 68.0, 102.0 0.23
PWK/PhJ f 47.5 6.99   11 2.11 0.147 35.0, 61.0 -0.58
PWK/PhJ m 51.1 7.11   13 1.97 0.139 40.0, 64.0 -1.0
RF/J f 72.6 10.0   16 2.5 0.138 49.0, 89.3 0.47
RF/J m 95.1 14.3   20 3.2 0.15 74.2, 122.0 0.6
RIIIS/J f 38.7 4.92   11 1.48 0.127 31.0, 45.0 -0.95
RIIIS/J m 49.9 8.9   13 2.47 0.178 32.0, 60.0 -1.04
SEA/GnJ f 47.1 6.33   8 2.24 0.134 36.0, 54.0 -0.6
SEA/GnJ m 79.8 10.9   10 3.43 0.136 66.0, 94.0 0.04
SJL/J f 36.6 4.12   10 1.3 0.112 31.0, 44.0 -1.04
SJL/J m 61.3 5.15   9 1.72 0.0839 53.0, 67.0 -0.63
SM/J f 49.5 5.99   13 1.66 0.121 42.0, 62.0 -0.5
SM/J m 71.5 6.83   11 2.06 0.0956 60.0, 85.0 -0.26
SPRET/EiJ f 101.0 11.2   11 3.37 0.111 82.0, 114.0 1.66
SPRET/EiJ m 127.0 13.7   10 4.33 0.108 100.0, 152.0 1.76
SWR/J f 44.0 14.0   10 4.43 0.318 20.0, 66.0 -0.73
SWR/J m 70.5 13.9   15 3.6 0.198 44.0, 97.0 -0.3
WSB/EiJ f 70.1 6.17   10 1.95 0.0881 59.0, 81.0 0.36
WSB/EiJ m 108.0 8.56   9 2.85 0.0796 95.0, 118.0 1.07


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 83.9348 2.8538 89.5353 78.3342
129S1/SvImJ m 113.5556 4.5621 122.5087 104.6024
A/J f 46.7 4.328 55.1937 38.2063
A/J m 51.75 3.9509 59.5036 43.9964
AKR/J f 59.5667 3.2259 65.8975 53.2359
AKR/J m 65.76 4.328 74.2537 57.2663
BALB/cByJ f 55.3333 3.2259 61.6641 49.0025
BALB/cByJ m 80.5333 3.5338 87.4684 73.5983
BTBR T+ Itpr3tf/J f 64.4545 4.1266 72.5529 56.3561
BTBR T+ Itpr3tf/J m 87.3333 4.5621 96.2865 78.3802
BUB/BnJ f 43.0 4.328 51.4937 34.5063
BUB/BnJ m 81.02 4.328 89.5137 72.5263
C3H/HeJ f 79.1222 4.5621 88.0753 70.1691
C3H/HeJ m 107.2222 4.5621 116.1753 98.2691
C57BL/10J f 50.95 2.9179 56.6764 45.2236
C57BL/10J m 22.6911 4.5621 31.6442 13.738
C57BL/6J f 37.92 2.7373 43.2919 32.5481
C57BL/6J m 59.0455 4.1266 67.1439 50.9471
C57BLKS/J f 51.74 4.328 60.2337 43.2463
C57BLKS/J m 64.3333 3.9509 72.087 56.5797
C57BR/cdJ f 46.7756 4.5621 55.7287 37.8224
C57BR/cdJ m 60.0769 3.7959 67.5264 52.6275
C57L/J f 42.4667 3.5338 49.4017 35.5316
C57L/J m 46.6091 2.9179 52.3355 40.8827
C58/J f 62.2 4.328 70.6937 53.7063
C58/J m 73.1158 3.1398 79.2778 66.9538
CAST/EiJ f 36.6364 4.1266 44.7348 28.538
CAST/EiJ m 51.0143 3.6578 58.1928 43.8358
CBA/J f 64.0 4.328 72.4937 55.5063
CBA/J m 84.25 4.8388 93.7462 74.7538
CE/J f 58.9091 4.1266 67.0075 50.8107
CE/J m 66.6 4.328 75.0937 58.1063
CZECHII/EiJ f 50.8889 4.5621 59.842 41.9358
CZECHII/EiJ m 56.6364 4.1266 64.7348 48.538
DBA/1J f 47.35 4.8388 56.8462 37.8538
DBA/1J m 62.3533 3.5338 69.2884 55.4183
DBA/2J f 40.3 4.328 48.7937 31.8063
DBA/2J m 75.5 3.9509 83.2536 67.7464
FVB/NJ f 98.3 4.328 106.7937 89.8063
FVB/NJ m 129.7692 3.7959 137.2187 122.3198
I/LnJ f 33.9583 3.9509 41.712 26.2047
I/LnJ m 59.0077 3.7959 66.4571 51.5582
JF1/MsJ f 48.8 4.8388 58.2962 39.3038
JF1/MsJ m 57.9091 4.1266 66.0075 49.8107
KK/HlJ f 147.3333 4.5621 156.2865 138.3802
KK/HlJ m 136.9 4.328 145.3937 128.4063
LP/J f 57.8125 3.4216 64.5273 51.0977
LP/J m 71.3875 4.8388 80.8837 61.8913
MA/MyJ f 76.43 4.328 84.9237 67.9363
MA/MyJ m 114.1818 4.1266 122.2802 106.0834
MOLF/EiJ f 49.1538 3.7959 56.6033 41.7044
MOLF/EiJ m 55.2 3.5338 62.1351 48.2649
MSM/MsJ f 73.4417 3.9509 81.1953 65.688
MSM/MsJ m 69.925 3.9509 77.6786 62.1714
NOD/ShiLtJ f 69.23 4.328 77.7237 60.7363
NOD/ShiLtJ m 86.8333 3.2259 93.1641 80.5025
NON/ShiLtJ f 71.6 4.328 80.0937 63.1063
NON/ShiLtJ m 109.15 3.6578 116.3285 101.9715
NZB/BlNJ f 109.9455 4.1266 118.0439 101.8471
NZB/BlNJ m 142.5556 4.5621 151.5087 133.6024
NZW/LacJ f 112.0 5.5874 122.9653 101.0347
NZW/LacJ m 118.5 4.328 126.9937 110.0063
PERA/EiJ f 47.25 4.8388 56.7462 37.7538
PERA/EiJ m 47.3333 4.5621 56.2865 38.3802
PL/J f 55.8391 2.8538 61.4397 50.2386
PL/J m 85.0895 3.1398 91.2514 78.9275
PWK/PhJ f 47.5455 4.1266 55.6439 39.4471
PWK/PhJ m 51.0769 3.7959 58.5264 43.6275
RF/J f 72.5688 3.4216 79.2836 65.8539
RF/J m 95.1 3.0603 101.1059 89.0941
RIIIS/J f 38.7273 4.1266 46.8257 30.6289
RIIIS/J m 49.8769 3.7959 57.3264 42.4275
SEA/GnJ f 47.125 4.8388 56.6212 37.6288
SEA/GnJ m 79.8 4.328 88.2937 71.3063
SJL/J f 36.6 4.328 45.0937 28.1063
SJL/J m 61.3333 4.5621 70.2865 52.3802
SM/J f 49.4615 3.7959 56.911 42.0121
SM/J m 71.4545 4.1266 79.5529 63.3561
SPRET/EiJ f 101.0 4.1266 109.0984 92.9016
SPRET/EiJ m 127.0 4.328 135.4937 118.5063
SWR/J f 44.0 4.328 52.4937 35.5063
SWR/J m 70.4667 3.5338 77.4017 63.5316
WSB/EiJ f 70.1 4.328 78.5937 61.6063
WSB/EiJ m 107.5556 4.5621 116.5087 98.6024


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 98.7452 2.6906 104.0254 93.4649
A/J both 49.225 2.9301 54.9752 43.4748
AKR/J both 62.6633 2.699 67.9601 57.3666
BALB/cByJ both 67.9333 2.3924 72.6284 63.2383
BTBR T+ Itpr3tf/J both 75.8939 3.0758 81.9301 69.8577
BUB/BnJ both 62.01 3.0603 68.0159 56.0041
C3H/HeJ both 93.1722 3.2259 99.503 86.8414
C57BL/10J both 36.8206 2.7077 42.1345 31.5066
C57BL/6J both 48.4827 2.4759 53.3418 43.6237
C57BLKS/J both 58.0367 2.9301 63.7869 52.2864
C57BR/cdJ both 53.4262 2.9674 59.2497 47.6027
C57L/J both 44.5379 2.2914 49.0347 40.041
C58/J both 67.6579 2.6735 72.9046 62.4112
CAST/EiJ both 43.8253 2.7572 49.2363 38.4144
CBA/J both 74.125 3.246 80.4953 67.7547
CE/J both 62.7545 2.99 68.6224 56.8867
CZECHII/EiJ both 53.7626 3.0758 59.7988 47.7264
DBA/1J both 54.8517 2.9959 60.7311 48.9722
DBA/2J both 57.9 2.9301 63.6502 52.1498
FVB/NJ both 114.0346 2.8784 119.6834 108.3858
I/LnJ both 46.483 2.7394 51.8592 41.1068
JF1/MsJ both 53.3545 3.1797 59.5948 47.1143
KK/HlJ both 142.1167 3.1442 148.2872 135.9462
LP/J both 64.6 2.9632 70.4152 58.7848
MA/MyJ both 95.3059 2.99 101.1738 89.4381
MOLF/EiJ both 52.1769 2.5931 57.2659 47.088
MSM/MsJ both 71.6833 2.7937 77.166 66.2007
NOD/ShiLtJ both 78.0317 2.699 83.3284 72.7349
NON/ShiLtJ both 90.375 2.8333 95.9354 84.8146
NZB/BlNJ both 126.2505 3.0758 132.2867 120.2143
NZW/LacJ both 115.25 3.5338 122.1851 108.3149
PERA/EiJ both 47.2917 3.3252 53.8173 40.766
PL/J both 70.4643 2.1215 74.6277 66.3009
PWK/PhJ both 49.3112 2.8034 54.813 43.8094
RF/J both 83.8344 2.2953 88.3388 79.3299
RIIIS/J both 44.3021 2.8034 49.8039 38.8003
SEA/GnJ both 63.4625 3.246 69.8328 57.0922
SJL/J both 48.9667 3.1442 55.1372 42.7962
SM/J both 60.458 2.8034 65.9598 54.9563
SPRET/EiJ both 114.0 2.99 119.8679 108.1321
SWR/J both 57.2333 2.7937 62.716 51.7507
WSB/EiJ both 88.8278 3.1442 94.9983 82.6573




  GWAS USING LINEAR MIXED MODELS