Project measure / variable:   Threadgill1   CYP1A2_ctrl

ID, description, units MPD:19483   CYP1A2_ctrl   cytochrome P450 1A2 isoform   [pmol/mg]  control  
acetaminophen study
Data set, strains Threadgill1   inbred w/CC7   36 strains     sex: m     age: 8-12wks
Procedure biomarker quantification
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  STRAIN COMPARISON PLOT
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Threadgill1 - cytochrome P450 1A2 isoform control



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested36 strains
Mean of the strain means180   pmol/mg
Median of the strain means182   pmol/mg
SD of the strain means± 58.9
Coefficient of variation (CV)0.327
Min–max range of strain means61.0   –   304   pmol/mg
Mean sample size per strain1.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 28 213114.1731 7611.2205 0.9756 0.5234
Residuals 32 249649.6 7801.55


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 200.0 162.0   2   114.0 0.808 86.0, 315.0 0.34
A/J m 137.0 32.5   2   23.0 0.237 114.0, 160.0 -0.73
AKR/J m 150.0 5.66   2   4.0 0.0377 146.0, 154.0 -0.51
B6C3F1/J m 197.0 43.8   2   31.0 0.223 166.0, 228.0 0.28
BALB/cByJ m 197.0 120.0   2   85.0 0.61 112.0, 282.0 0.28
BTBR T+ Itpr3tf/J m 103.0 58.3   2   41.2 0.567 61.6, 144.0 -1.31
BUB/BnJ m 132.0 0.0   1   0.0 0.0 132.0, 132.0 -0.82
C3H/HeJ m 167.0 90.5   2   64.0 0.542 103.0, 231.0 -0.22
C57BL/10J m 174.0 58.0   2   41.0 0.333 133.0, 215.0 -0.11
C57BL/6J m 216.0 136.0   2   96.5 0.633 119.0, 312.0 0.61
C57BLKS/J m 85.5 23.3   2   16.5 0.273 69.0, 102.0 -1.61
C57BR/cdJ m 164.0 46.0   2   32.5 0.281 131.0, 196.0 -0.28
C57L/J m 61.0 13.4   2   9.5 0.22 51.5, 70.5 -2.03
CBA/J m 211.0 162.0   2   114.0 0.767 96.5, 325.0 0.52
CZECHII/EiJ m 210.0 0.0   1   0.0 0.0 210.0, 210.0 0.51
DBA/2J m 204.0 36.8   2   26.0 0.18 178.0, 230.0 0.4
FVB/NJ m 171.0 0.0   1   0.0 0.0 171.0, 171.0 -0.16
JF1/MsJ m 304.0 110.0   2   78.0 0.363 226.0, 382.0 2.1
KK/HlJ m 240.0 37.5   2   26.5 0.156 213.0, 266.0 1.02
LP/J m 104.0 71.9   3 41.5 0.69 22.5, 158.0 -1.3
MA/MyJ m 166.0 113.0   2   80.2 0.685 85.5, 246.0 -0.24
MSM/MsJ m 263.0 38.2   2   27.0 0.145 236.0, 290.0 1.41
NOD/ShiLtJ m 266.0 156.0   2   110.0 0.585 156.0, 376.0 1.46
NON/ShiLtJ m 224.0 0.0   1   0.0 0.0 224.0, 224.0 0.74
NZO/HlLtJ m 213.0 80.6   2   57.0 0.378 156.0, 270.0 0.56
NZW/LacJ m 191.0 12.7   2   9.0 0.0666 182.0, 200.0 0.18
PERA/EiJ m 152.0 130.0   3 74.9 0.853 49.5, 298.0 -0.48
P/J m 118.0 83.1   2   58.8 0.703 59.5, 177.0 -1.06
PL/J m 186.0 0.0   1   0.0 0.0 186.0, 186.0 0.1
PWD/PhJ m 281.0 11.3   2   8.0 0.0403 273.0, 289.0 1.71
RIIIS/J m 288.0 0.0   1   0.0 0.0 288.0, 288.0 1.83
SEA/GnJ m 102.0 81.0   2   57.2 0.796 44.5, 159.0 -1.33
SJL/J m 107.0 80.5   2   56.9 0.751 50.2, 164.0 -1.24
SM/J m 180.0 0.0   1   0.0 0.0 180.0, 180.0 0.0
SWR/J m 184.0 91.3   3 52.7 0.495 79.0, 240.0 0.06
WSB/EiJ m 140.0 50.9   2   36.0 0.364 104.0, 176.0 -0.68


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ m 200.5 62.4562 327.7191 73.2809
A/J m 137.0 62.4562 264.2191 9.7809
AKR/J m 150.0 62.4562 277.2191 22.7809
B6C3F1/J m 197.0 62.4562 324.2191 69.7809
BALB/cByJ m 197.0 62.4562 324.2191 69.7809
BTBR T+ Itpr3tf/J m 102.8 62.4562 230.0191 0.0
C3H/HeJ m 167.0 62.4562 294.2191 39.7809
C57BL/10J m 174.0 62.4562 301.2191 46.7809
C57BL/6J m 215.5 62.4562 342.7191 88.2809
C57BLKS/J m 85.5 62.4562 212.7191 0.0
C57BR/cdJ m 163.5 62.4562 290.7191 36.2809
C57L/J m 61.0 62.4562 188.2191 0.0
CBA/J m 210.75 62.4562 337.9691 83.5309
DBA/2J m 204.0 62.4562 331.2191 76.7809
JF1/MsJ m 304.0 62.4562 431.2191 176.7809
KK/HlJ m 239.5 62.4562 366.7191 112.2809
LP/J m 104.1667 50.9953 208.0406 0.2927
MA/MyJ m 165.75 62.4562 292.9691 38.5309
MSM/MsJ m 263.0 62.4562 390.2191 135.7809
NOD/ShiLtJ m 266.0 62.4562 393.2191 138.7809
NZO/HlLtJ m 213.0 62.4562 340.2191 85.7809
NZW/LacJ m 191.0 62.4562 318.2191 63.7809
PERA/EiJ m 152.1667 50.9953 256.0406 48.2927
P/J m 118.25 62.4562 245.4691 0.0
PWD/PhJ m 281.0 62.4562 408.2191 153.7809
SEA/GnJ m 101.75 62.4562 228.9691 0.0
SJL/J m 107.1 62.4562 234.3191 0.0
SWR/J m 184.3333 50.9953 288.2073 80.4594
WSB/EiJ m 140.0 62.4562 267.2191 12.7809




  GWAS USING LINEAR MIXED MODELS