Project measure / variable:   Threadgill1   GSHratio_Rx300

ID, description, units MPD:19481   GSHratio_Rx300   ratio of reduced (GSH) to oxidized (GSSG) glutathione   [ratio]  post-Rx 300mg/kg  
acetaminophen study
Data set, strains Threadgill1   inbred w/CC7   36 strains     sex: m     age: 8-17wks
Procedure metabolite quantification
Ontology mappings

  •   Or, add this measure to your collection.
       
  •     no folder
  •     put it in new folder  

  STRAIN COMPARISON PLOT
Dimensions Width:   px    Height:   px
Download Plot   
Visualization Options

Threadgill1 - ratio of reduced (GSH) to oxidized (GSSG) glutathione post-Rx 300mg/kg



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested36 strains
Mean of the strain means21.6   ratio
Median of the strain means18.0   ratio
SD of the strain means± 21.7
Coefficient of variation (CV)1.01
Min–max range of strain means-32.5   –   115   ratio
Mean sample size per strain3.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 34 56130.0627 1650.8842 1.73 0.0194
Residuals 99 94469.8534 954.2409


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 16.4 6.96   5 3.11 0.426 7.76, 24.3 -0.24
A/J m 16.4 3.76   4 1.88 0.229 13.2, 21.8 -0.24
AKR/J m 19.9 5.33   4 2.66 0.267 15.1, 27.5 -0.08
B6C3F1/J m 14.8 2.49   4 1.24 0.168 11.1, 16.3 -0.31
BALB/cByJ m 67.3 116.0   4 58.2 1.73 6.1, 242.0 2.11
BTBR T+ Itpr3tf/J m 27.7 28.5   3 16.4 1.03 10.1, 60.6 0.28
BUB/BnJ m -32.5 36.3   4 18.1 -1.12 -60.5, 20.3 -2.49
C3H/HeJ m 18.3 3.06   4 1.53 0.167 14.7, 21.5 -0.15
C57BL/10J m 16.2 11.2   4 5.58 0.689 9.58, 32.9 -0.25
C57BL/6J m 19.8 4.7   4 2.35 0.238 13.9, 25.3 -0.08
C57BLKS/J m 15.6 1.64   4 0.822 0.105 13.2, 16.9 -0.27
C57BR/cdJ m -6.76 44.1   4 22.0 -6.52 -72.4, 22.0 -1.3
C57L/J m 14.3 4.43   3 2.56 0.311 10.4, 19.1 -0.33
CAST/EiJ m 115.0 123.0   3 70.8 1.07 19.5, 253.0 4.3
CBA/J m 17.6 2.09   4 1.04 0.119 15.6, 20.5 -0.18
CZECHII/EiJ m 35.3 5.16   3 2.98 0.146 31.5, 41.2 0.63
DBA/2J m 16.1 5.71   4 2.85 0.354 9.57, 22.9 -0.25
FVB/NJ m 13.6 2.08   4 1.04 0.153 11.3, 15.6 -0.37
JF1/MsJ m 15.6 4.07   3 2.35 0.261 11.3, 19.4 -0.27
KK/HlJ m 33.2 30.2   3 17.4 0.908 9.9, 67.3 0.54
LP/J m 8.09 2.88   4 1.44 0.356 6.43, 12.4 -0.62
MA/MyJ m 19.4 11.6   3 6.7 0.597 12.0, 32.8 -0.1
MSM/MsJ m 10.3 1.5   4 0.751 0.146 8.83, 12.4 -0.52
NOD/ShiLtJ m 23.8 4.53   4 2.27 0.191 18.3, 27.5 0.1
NON/ShiLtJ m 11.2 0.698   4 0.349 0.0623 10.6, 12.2 -0.48
NZO/HlLtJ m 12.4 3.05   5 1.36 0.245 9.44, 16.8 -0.42
NZW/LacJ m 25.1 19.5   5 8.73 0.777 13.5, 59.7 0.16
PERA/EiJ m 19.9 13.9   4 6.95 0.698 10.2, 39.8 -0.08
PL/J m 15.5 5.91   4 2.95 0.382 9.54, 22.2 -0.28
PWD/PhJ m 23.9 3.74   4 1.87 0.157 19.2, 27.6 0.11
RIIIS/J m 20.0 2.88   4 1.44 0.144 16.1, 22.9 -0.07
SEA/GnJ m 10.4 1.09   3 0.63 0.105 9.7, 11.7 -0.51
SJL/J m 25.5 9.36   4 4.68 0.367 18.9, 38.9 0.18
SM/J m 42.0 44.7   3 25.8 1.07 13.6, 93.5 0.94
SWR/J m 31.9 28.8   4 14.4 0.902 12.9, 74.7 0.48
WSB/EiJ m 22.7 0.0   1   0.0 0.0 22.7, 22.7 0.05


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ m 16.352 13.8148 43.7635 -11.0595
A/J m 16.425 15.4454 47.072 -14.222
AKR/J m 19.95 15.4454 50.597 -10.697
B6C3F1/J m 14.8 15.4454 45.447 -15.847
BALB/cByJ m 67.325 15.4454 97.972 36.678
BTBR T+ Itpr3tf/J m 27.7333 17.8348 63.1215 -7.6548
BUB/BnJ m -32.525 15.4454 -1.878 -63.172
C3H/HeJ m 18.275 15.4454 48.922 -12.372
C57BL/10J m 16.195 15.4454 46.842 -14.452
C57BL/6J m 19.75 15.4454 50.397 -10.897
C57BLKS/J m 15.6 15.4454 46.247 -15.047
C57BR/cdJ m -6.755 15.4454 23.892 -37.402
C57L/J m 14.2667 17.8348 49.6548 -21.1215
CAST/EiJ m 114.6 17.8348 149.9881 79.2119
CBA/J m 17.6 15.4454 48.247 -13.047
CZECHII/EiJ m 35.3333 17.8348 70.7215 -0.0548
DBA/2J m 16.1175 15.4454 46.7645 -14.5295
FVB/NJ m 13.6 15.4454 44.247 -17.047
JF1/MsJ m 15.5667 17.8348 50.9548 -19.8215
KK/HlJ m 33.2333 17.8348 68.6215 -2.1548
LP/J m 8.09 15.4454 38.737 -22.557
MA/MyJ m 19.4333 17.8348 54.8215 -15.9548
MSM/MsJ m 10.31 15.4454 40.957 -20.337
NOD/ShiLtJ m 23.775 15.4454 54.422 -6.872
NON/ShiLtJ m 11.2 15.4454 41.847 -19.447
NZO/HlLtJ m 12.448 13.8148 39.8595 -14.9635
NZW/LacJ m 25.12 13.8148 52.5315 -2.2915
PERA/EiJ m 19.9 15.4454 50.547 -10.747
PL/J m 15.46 15.4454 46.107 -15.187
PWD/PhJ m 23.85 15.4454 54.497 -6.797
RIIIS/J m 19.975 15.4454 50.622 -10.672
SEA/GnJ m 10.4467 17.8348 45.8348 -24.9415
SJL/J m 25.525 15.4454 56.172 -5.122
SM/J m 41.9667 17.8348 77.3548 6.5785
SWR/J m 31.875 15.4454 62.522 1.228




  GWAS USING LINEAR MIXED MODELS