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Project measure / variable:   Threadgill1   GSSG_Rx300

ID, description, units MPD:19477   GSSG_Rx300   oxidized glutathione (GSSG)   [µmol/g]  post-Rx 300mg/kg  
acetaminophen study
Data set, strains Threadgill1   inbred w/CC7   36 strains     sex: m     age: 8-17wks
Procedure metabolite quantification
Ontology mappings

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  STRAIN COMPARISON PLOT
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Threadgill1 - oxidized glutathione (GSSG) post-Rx 300mg/kg



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested36 strains
Mean of the strain means0.140   µmol/g
Median of the strain means0.120   µmol/g
SD of the strain means± 0.0834
Coefficient of variation (CV)0.597
Min–max range of strain means-0.0130   –   0.398   µmol/g
Mean sample size per strain3.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 34 0.8672 0.0255 3.8454 < 0.0001
Residuals 100 0.6633 0.0066


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 0.162 0.093   5 0.0416 0.573 0.103, 0.325 0.27
A/J m 0.136 0.0759   4 0.038 0.56 0.0775, 0.247 -0.04
AKR/J m 0.125 0.0724   4 0.0362 0.579 0.0766, 0.232 -0.18
B6C3F1/J m 0.199 0.0596   4 0.0298 0.299 0.131, 0.264 0.71
BALB/cByJ m 0.049 0.0357   4 0.0179 0.729 0.0022, 0.0866 -1.09
BTBR T+ Itpr3tf/J m 0.103 0.0753   3 0.0435 0.733 0.0309, 0.181 -0.44
BUB/BnJ m -0.013 0.0986   4 0.0493 -7.6 -0.0723, 0.134 -1.83
C3H/HeJ m 0.108 0.0228   4 0.0114 0.212 0.0792, 0.128 -0.38
C57BL/10J m 0.0905 0.0843   4 0.0422 0.932 0.0064, 0.175 -0.59
C57BL/6J m 0.0881 0.0614   4 0.0307 0.697 0.0185, 0.15 -0.62
C57BLKS/J m 0.135 0.0322   4 0.0161 0.239 0.102, 0.174 -0.06
C57BR/cdJ m 0.088 0.124   4 0.062 1.41 -0.0838, 0.211 -0.62
C57L/J m 0.0857 0.0691   4 0.0346 0.806 -0.65
CAST/EiJ m 0.0804 0.0761   3 0.0439 0.947 0.0244, 0.167 -0.71
CBA/J m 0.11 0.0297   4 0.0149 0.269 0.0841, 0.153 -0.36
CZECHII/EiJ m 0.0987 0.086   3 0.0496 0.871 0.008, 0.179 -0.49
DBA/2J m 0.122 0.0796   4 0.0398 0.655 0.0528, 0.214 -0.21
FVB/NJ m 0.13 0.0578   4 0.0289 0.445 0.0848, 0.206 -0.12
JF1/MsJ m 0.173 0.135   3 0.078 0.781 0.0177, 0.264 0.4
KK/HlJ m 0.0654 0.0559   3 0.0323 0.854 0.0114, 0.123 -0.89
LP/J m 0.16 0.0181   4 0.00906 0.113 0.134, 0.175 0.24
MA/MyJ m 0.179 0.132   3 0.0764 0.738 0.0717, 0.327 0.47
MSM/MsJ m 0.383 0.107   4 0.0537 0.281 0.271, 0.475 2.92
NOD/ShiLtJ m 0.213 0.0815   4 0.0408 0.383 0.115, 0.314 0.88
NON/ShiLtJ m 0.143 0.0623   4 0.0312 0.435 0.095, 0.231 0.04
NZO/HlLtJ m 0.114 0.0446   5 0.0199 0.391 0.0757, 0.19 -0.31
NZW/LacJ m 0.0769 0.049   5 0.0219 0.637 0.0456, 0.164 -0.75
PERA/EiJ m 0.294 0.212   4 0.106 0.719 0.0919, 0.528 1.85
PL/J m 0.118 0.0792   4 0.0396 0.669 0.0341, 0.216 -0.26
PWD/PhJ m 0.166 0.0475   4 0.0237 0.285 0.125, 0.217 0.32
RIIIS/J m 0.233 0.0674   4 0.0337 0.29 0.155, 0.316 1.12
SEA/GnJ m 0.398 0.0741   3 0.0428 0.186 0.315, 0.458 3.1
SJL/J m 0.111 0.034   4 0.017 0.306 0.0616, 0.138 -0.34
SM/J m 0.15 0.0923   3 0.0533 0.615 0.0439, 0.212 0.12
SWR/J m 0.0989 0.0764   4 0.0382 0.772 0.0046, 0.181 -0.49
WSB/EiJ m 0.0541 0.0   1   0.0 0.0 0.0541, 0.0541 -1.03


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ m 0.1624 0.0364 0.2347 0.0901
A/J m 0.1356 0.0407 0.2164 0.0548
AKR/J m 0.125 0.0407 0.2058 0.0442
B6C3F1/J m 0.1992 0.0407 0.28 0.1185
BALB/cByJ m 0.049 0.0407 0.1298 -0.0318
BTBR T+ Itpr3tf/J m 0.1027 0.047 0.196 0.0094
BUB/BnJ m -0.013 0.0407 0.0678 -0.0938
C3H/HeJ m 0.1076 0.0407 0.1884 0.0268
C57BL/10J m 0.0905 0.0407 0.1713 0.0097
C57BL/6J m 0.0881 0.0407 0.1689 0.0073
C57BLKS/J m 0.1347 0.0407 0.2155 0.054
C57BR/cdJ m 0.088 0.0407 0.1688 0.0073
C57L/J m 0.0857 0.0407 0.1665 0.0049
CAST/EiJ m 0.0804 0.047 0.1737 -0.0129
CBA/J m 0.1103 0.0407 0.1911 0.0295
CZECHII/EiJ m 0.0987 0.047 0.192 0.0054
DBA/2J m 0.1216 0.0407 0.2023 0.0408
FVB/NJ m 0.13 0.0407 0.2108 0.0492
JF1/MsJ m 0.1729 0.047 0.2662 0.0796
KK/HlJ m 0.0654 0.047 0.1587 -0.0279
LP/J m 0.16 0.0407 0.2408 0.0792
MA/MyJ m 0.1792 0.047 0.2725 0.0859
MSM/MsJ m 0.383 0.0407 0.4638 0.3022
NOD/ShiLtJ m 0.2127 0.0407 0.2935 0.132
NON/ShiLtJ m 0.1432 0.0407 0.224 0.0625
NZO/HlLtJ m 0.1138 0.0364 0.1861 0.0416
NZW/LacJ m 0.0769 0.0364 0.1492 0.0046
PERA/EiJ m 0.294 0.0407 0.3748 0.2132
PL/J m 0.1184 0.0407 0.1992 0.0376
PWD/PhJ m 0.1665 0.0407 0.2473 0.0857
RIIIS/J m 0.2327 0.0407 0.3135 0.152
SEA/GnJ m 0.3977 0.047 0.491 0.3044
SJL/J m 0.1114 0.0407 0.1922 0.0306
SM/J m 0.15 0.047 0.2433 0.0567
SWR/J m 0.0989 0.0407 0.1797 0.0182




  GWAS USING LINEAR MIXED MODELS