Project measure / variable:   Threadgill1   GSH_Rx300

ID, description, units MPD:19475   GSH_Rx300   reduced glutathione (GSH)   [µmol/g]  post-Rx 300mg/kg  
acetaminophen study
Data set, strains Threadgill1   inbred w/CC7   36 strains     sex: m     age: 8-17wks
Procedure metabolite quantification
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  STRAIN COMPARISON PLOT
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Threadgill1 - reduced glutathione (GSH) post-Rx 300mg/kg



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested36 strains
Mean of the strain means2.45   µmol/g
Median of the strain means2.10   µmol/g
SD of the strain means± 1.14
Coefficient of variation (CV)0.466
Min–max range of strain means0.553   –   4.83   µmol/g
Mean sample size per strain3.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 34 167.6881 4.932 3.6512 < 0.0001
Residuals 100 135.0774 1.3508


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 2.82 2.3   5 1.03 0.815 0.799, 6.68 0.32
A/J m 2.11 0.873   4 0.436 0.414 1.24, 3.27 -0.3
AKR/J m 2.29 0.833   4 0.417 0.363 1.65, 3.51 -0.14
B6C3F1/J m 2.91 0.951   4 0.476 0.327 2.12, 4.29 0.4
BALB/cByJ m 0.553 0.0989   4 0.0495 0.179 0.454, 0.69 -1.66
BTBR T+ Itpr3tf/J m 1.7 0.66   3 0.381 0.388 0.972, 2.26 -0.66
BUB/BnJ m 3.02 0.91   4 0.455 0.301 2.38, 4.37 0.5
C3H/HeJ m 1.93 0.254   4 0.127 0.132 1.58, 2.13 -0.46
C57BL/10J m 0.984 0.823   4 0.412 0.837 0.211, 1.71 -1.28
C57BL/6J m 1.69 1.24   4 0.622 0.735 0.383, 3.23 -0.67
C57BLKS/J m 2.09 0.516   4 0.258 0.247 1.71, 2.85 -0.32
C57BR/cdJ m 3.09 2.1   4 1.05 0.677 1.21, 6.07 0.56
C57L/J m 1.19 0.942   4 0.471 0.795 -1.1
CAST/EiJ m 4.32 1.61   3 0.927 0.371 3.26, 6.17 1.64
CBA/J m 1.98 0.786   4 0.393 0.398 1.41, 3.13 -0.41
CZECHII/EiJ m 3.57 2.97   3 1.71 0.831 0.253, 5.97 0.98
DBA/2J m 1.7 0.878   4 0.439 0.518 0.953, 2.96 -0.66
FVB/NJ m 1.7 0.596   4 0.298 0.35 1.28, 2.56 -0.66
JF1/MsJ m 2.37 1.8   3 1.04 0.761 0.342, 3.79 -0.07
KK/HlJ m 1.12 0.324   3 0.187 0.288 0.764, 1.39 -1.16
LP/J m 1.31 0.542   4 0.271 0.413 0.893, 2.1 -1.0
MA/MyJ m 2.72 1.07   3 0.617 0.393 1.88, 3.92 0.24
MSM/MsJ m 4.04 1.57   4 0.785 0.388 2.4, 5.9 1.39
NOD/ShiLtJ m 4.83 1.31   4 0.657 0.272 3.16, 6.02 2.08
NON/ShiLtJ m 1.64 0.828   4 0.414 0.505 1.04, 2.82 -0.71
NZO/HlLtJ m 1.37 0.43   5 0.192 0.315 1.03, 1.88 -0.95
NZW/LacJ m 1.7 1.13   5 0.506 0.666 0.819, 3.45 -0.66
PERA/EiJ m 4.02 1.15   4 0.573 0.285 2.67, 5.39 1.37
PL/J m 1.6 0.918   4 0.459 0.573 0.758, 2.67 -0.74
PWD/PhJ m 3.91 0.975   4 0.487 0.249 2.83, 5.12 1.28
RIIIS/J m 4.56 1.05   4 0.523 0.229 3.27, 5.66 1.85
SEA/GnJ m 4.16 0.918   3 0.53 0.221 3.13, 4.9 1.5
SJL/J m 2.62 0.397   4 0.199 0.152 2.27, 3.17 0.15
SM/J m 3.54 0.621   3 0.358 0.175 2.88, 4.11 0.95
SWR/J m 1.82 1.42   4 0.712 0.782 0.346, 3.76 -0.55
WSB/EiJ m 1.23 0.0   1   0.0 0.0 1.23, 1.23 -1.07


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ m 2.8218 0.5198 3.853 1.7906
A/J m 2.11 0.5811 3.2629 0.9571
AKR/J m 2.2925 0.5811 3.4454 1.1396
B6C3F1/J m 2.9075 0.5811 4.0604 1.7546
BALB/cByJ m 0.5528 0.5811 1.7057 0.0
BTBR T+ Itpr3tf/J m 1.7007 0.671 3.0319 0.3694
BUB/BnJ m 3.0225 0.5811 4.1754 1.8696
C3H/HeJ m 1.925 0.5811 3.0779 0.7721
C57BL/10J m 0.9835 0.5811 2.1364 0.0
C57BL/6J m 1.6908 0.5811 2.8437 0.5378
C57BLKS/J m 2.09 0.5811 3.2429 0.9371
C57BR/cdJ m 3.095 0.5811 4.2479 1.9421
C57L/J m 1.1853 0.5811 2.3382 0.0323
CAST/EiJ m 4.3233 0.671 5.6546 2.9921
CBA/J m 1.975 0.5811 3.1279 0.8221
CZECHII/EiJ m 3.5677 0.671 4.8989 2.2364
DBA/2J m 1.6958 0.5811 2.8487 0.5428
FVB/NJ m 1.7 0.5811 2.8529 0.5471
JF1/MsJ m 2.3707 0.671 3.7019 1.0394
KK/HlJ m 1.1247 0.671 2.4559 0.0
LP/J m 1.3108 0.5811 2.4637 0.1578
MA/MyJ m 2.7167 0.671 4.0479 1.3854
MSM/MsJ m 4.04 0.5811 5.1929 2.8871
NOD/ShiLtJ m 4.835 0.5811 5.9879 3.6821
NON/ShiLtJ m 1.64 0.5811 2.7929 0.4871
NZO/HlLtJ m 1.366 0.5198 2.3972 0.3348
NZW/LacJ m 1.6972 0.5198 2.7284 0.666
PERA/EiJ m 4.0175 0.5811 5.1704 2.8646
PL/J m 1.6018 0.5811 2.7547 0.4488
PWD/PhJ m 3.91 0.5811 5.0629 2.7571
RIIIS/J m 4.5575 0.5811 5.7104 3.4046
SEA/GnJ m 4.1567 0.671 5.4879 2.8254
SJL/J m 2.62 0.5811 3.7729 1.4671
SM/J m 3.5433 0.671 4.8746 2.2121
SWR/J m 1.8215 0.5811 2.9744 0.6686




  GWAS USING LINEAR MIXED MODELS