Project measure / variable:   Threadgill1   BUN_Rx200

ID, description, units MPD:19443   BUN_Rx200   blood urea nitrogen (serum BUN)   [mg/dL]  dose: 200 mg/kg  
acetaminophen study
Data set, strains Threadgill1   inbred w/CC7   8 strains     sex: m     age: 8-17wks
Procedure metabolic panel
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  STRAIN COMPARISON PLOT
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Threadgill1 - blood urea nitrogen (serum BUN) dose: 200 mg/kg



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested8 strains
Mean of the strain means30.4   mg/dL
Median of the strain means22.1   mg/dL
SD of the strain means± 24.6
Coefficient of variation (CV)0.811
Min–max range of strain means17.8   –   90.7   mg/dL
Mean sample size per strain3.5   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 7 13135.8571 1876.551 6.7017 0.0004
Residuals 20 5600.25 280.0125


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
B6C3F1/J m 23.0 4.69   4 2.35 0.204 20.0, 30.0 -0.3
C3H/HeJ m 18.2 4.57   4 2.29 0.251 13.0, 24.0 -0.49
C57BL/10J m 24.7 4.16   3 2.4 0.169 20.0, 28.0 -0.23
CBA/J m 90.7 51.0   3 29.4 0.562 35.0, 135.0 2.45
DBA/2J m 19.2 2.5   4 1.25 0.13 16.0, 22.0 -0.45
LP/J m 21.3 10.4   3 6.01 0.488 13.0, 33.0 -0.37
NOD/ShiLtJ m 17.8 0.957   4 0.479 0.0539 17.0, 19.0 -0.51
SM/J m 28.0 1.73   3 1.0 0.0619 27.0, 30.0 -0.1


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
B6C3F1/J m 23.0 8.3668 40.4528 5.5472
C3H/HeJ m 18.25 8.3668 35.7028 0.7972
C57BL/10J m 24.6667 9.6611 44.8194 4.5139
CBA/J m 90.6667 9.6611 110.8194 70.5139
DBA/2J m 19.25 8.3668 36.7028 1.7972
LP/J m 21.3333 9.6611 41.4861 1.1806
NOD/ShiLtJ m 17.75 8.3668 35.2028 0.2972
SM/J m 28.0 9.6611 48.1528 7.8472




  GWAS USING LINEAR MIXED MODELS