Project measure / variable:   Threadgill1   liver_necrosis_Rx100

ID, description, units MPD:19405   liver_necrosis_Rx100   necrosis   [%]  dose: 100 mg/kg  
acetaminophen study
Data set, strains Threadgill1   inbred w/CC7   6 strains     sex: m     age: 8-17wks
Procedure histopathology
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  STRAIN COMPARISON PLOT
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Threadgill1 - necrosis dose: 100 mg/kg



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested6 strains
Mean of the strain means0.667   %
Median of the strain means0   %
SD of the strain means± 1.63
Coefficient of variation (CV)2.45
Min–max range of strain means0   –   4.00   %
Mean sample size per strain3.7   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 5 29.0909 5.8182 2.9091 0.047
Residuals 16 32.0 2.0


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
B6C3F1/J m 0.0 0.0   4 0.0 0.0 -0.41
C3H/HeJ m 0.0 0.0   4 0.0 0.0 -0.41
C57BL/10J m 0.0 0.0   4 0.0 0.0 -0.41
CBA/J m 4.0 5.66   2   4.0 1.41 2.04
DBA/2J m 0.0 0.0   4 0.0 0.0 -0.41
NOD/ShiLtJ m 0.0 0.0   4 0.0 0.0 -0.41


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
B6C3F1/J m 0.0 0.7071 1.499 -1.499
C3H/HeJ m 0.0 0.7071 1.499 -1.499
C57BL/10J m 0.0 0.7071 1.499 -1.499
CBA/J m 4.0 1.0 6.1199 1.8801
DBA/2J m 0.0 0.7071 1.499 -1.499
NOD/ShiLtJ m 0.0 0.7071 1.499 -1.499




  GWAS USING LINEAR MIXED MODELS