Project measure / variable:   Crabbe4   BEC_dowel15_8

ID, description, units MPD:19111   BEC_dowel15_8   blood ethanol concentration (BEC), 35 min post-injection, dowel (15.8 mm) test   [mg/mL]  
ethanol study
Data set, strains Crabbe4   inbred   8 strains     sex: both     age: 12-16wks
Procedure alcohol quantification
Ontology mappings

  STRAIN COMPARISON PLOT
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Crabbe4 - blood ethanol concentration (BEC), 35 min post-injection, dowel (15.8 mm) test



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means1.41   mg/mL 1.73   mg/mL
Median of the strain means1.39   mg/mL 1.70   mg/mL
SD of the strain means± 0.179 ± 0.339
Coefficient of variation (CV)0.127 0.196
Min–max range of strain means1.22   –   1.78   mg/mL 1.35   –   2.19   mg/mL
Mean sample size per strain3.6   mice 3.2   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 1.2406 1.2406 10.7612 0.0022
strain 7 2.5791 0.3684 3.196 0.009
sex:strain 7 0.9353 0.1336 1.159 0.3481
Residuals 39 4.4961 0.1153


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 1.38 0.266   4 0.133 0.192 1.09, 1.73 -0.2
129S1/SvImJ m 1.58 0.257   4 0.128 0.162 1.3, 1.84 -0.45
A/J f 1.41 0.272   4 0.136 0.193 1.06, 1.72 -0.03
A/J m 1.37 0.373   3 0.215 0.272 1.03, 1.77 -1.07
BALB/cByJ f 1.39 0.394   4 0.197 0.284 0.94, 1.9 -0.14
BALB/cByJ m 1.35 0.119   3 0.0689 0.0886 1.25, 1.48 -1.13
BTBR T+ Itpr3tf/J f 1.22 0.1   3 0.0578 0.0819 1.11, 1.3 -1.09
BTBR T+ Itpr3tf/J m 1.97 0.226   2   0.16 0.115 1.81, 2.13 0.7
C3H/HeJ f 1.22 0.142   4 0.0711 0.116 1.01, 1.31 -1.09
C3H/HeJ m 1.46 0.219   4 0.11 0.151 1.16, 1.69 -0.81
C57BL/6J f 1.53 0.0663   4 0.0332 0.0434 1.46, 1.62 0.64
C57BL/6J m 2.19 0.519   4 0.26 0.237 1.75, 2.91 1.34
DBA/2J f 1.78 0.21   4 0.105 0.118 1.51, 2.02 2.04
DBA/2J m 2.13 0.843   3 0.487 0.396 1.48, 3.08 1.17
FVB/NJ f 1.39 0.198   2   0.14 0.142 1.25, 1.53 -0.14
FVB/NJ m 1.82 0.448   3 0.259 0.247 1.3, 2.1 0.25


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 1.38 0.1698 1.7234 1.0366
129S1/SvImJ m 1.585 0.1698 1.9284 1.2416
A/J f 1.41 0.1698 1.7534 1.0666
A/J m 1.3733 0.196 1.7698 0.9768
BALB/cByJ f 1.385 0.1698 1.7284 1.0416
BALB/cByJ m 1.3467 0.196 1.7432 0.9502
BTBR T+ Itpr3tf/J f 1.2233 0.196 1.6198 0.8268
BTBR T+ Itpr3tf/J m 1.97 0.2401 2.4556 1.4844
C3H/HeJ f 1.2225 0.1698 1.5659 0.8791
C3H/HeJ m 1.455 0.1698 1.7984 1.1116
C57BL/6J f 1.53 0.1698 1.8734 1.1866
C57BL/6J m 2.1875 0.1698 2.5309 1.8441
DBA/2J f 1.7825 0.1698 2.1259 1.4391
DBA/2J m 2.1267 0.196 2.5232 1.7302
FVB/NJ f 1.39 0.2401 1.8756 0.9044
FVB/NJ m 1.8167 0.196 2.2132 1.4202


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 1.4825 0.12 1.7253 1.2397
A/J both 1.3917 0.1297 1.6539 1.1294
BALB/cByJ both 1.3658 0.1297 1.6281 1.1036
BTBR T+ Itpr3tf/J both 1.5967 0.155 1.9101 1.2832
C3H/HeJ both 1.3387 0.12 1.5816 1.0959
C57BL/6J both 1.8587 0.12 2.1016 1.6159
DBA/2J both 1.9546 0.1297 2.2168 1.6923
FVB/NJ both 1.6033 0.155 1.9168 1.2899




  GWAS USING LINEAR MIXED MODELS