Project measure / variable:   Crabbe4   gripbaseline

ID, description, units MPD:19106   gripbaseline   grip strength test: peak force applied   [g]  baseline  
ethanol study
Data set, strains Crabbe4   inbred   21 strains     sex: both     age: 7-12wks
Procedure grip strength
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  STRAIN COMPARISON PLOT
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Crabbe4 - grip strength test: peak force applied baseline



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested21 strains21 strains
Mean of the strain means106   g 127   g
Median of the strain means109   g 134   g
SD of the strain means± 19.0 ± 33.0
Coefficient of variation (CV)0.178 0.259
Min–max range of strain means58.0   –   136   g 51.1   –   185   g
Mean sample size per strain6.5   mice 5.7   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 30164.6958 30164.6958 70.8952 < 0.0001
strain 20 129320.5606 6466.028 15.1969 < 0.0001
sex:strain 20 39117.5909 1955.8795 4.5968 < 0.0001
Residuals 216 91904.3073 425.4829


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 122.0 5.68   6 2.32 0.0464 115.0, 132.0 0.82
129S1/SvImJ m 155.0 10.8   6 4.4 0.0694 139.0, 168.0 0.83
A/J f 122.0 9.63   6 3.93 0.0791 111.0, 139.0 0.82
A/J m 137.0 9.39   6 3.83 0.0686 124.0, 152.0 0.29
AKR/J f 109.0 15.5   6 6.33 0.143 83.4, 124.0 0.14
AKR/J m 130.0 9.84   6 4.02 0.0757 118.0, 145.0 0.08
BALB/cByJ f 131.0 23.2   6 9.47 0.177 84.8, 148.0 1.3
BALB/cByJ m 169.0 10.7   6 4.38 0.0635 149.0, 180.0 1.26
BTBR T+ Itpr3tf/J f 58.0 63.7   6 26.0 1.1 -2.55
BTBR T+ Itpr3tf/J m 115.0 15.9   5 7.11 0.138 106.0, 143.0 -0.38
C3H/HeJ f 107.0 28.1   6 11.5 0.263 81.1, 146.0 0.03
C3H/HeJ m 165.0 11.6   6 4.72 0.07 152.0, 183.0 1.14
C57BL/6J f 119.0 14.2   12 4.09 0.119 98.7, 142.0 0.66
C57BL/6J m 143.0 22.3   6 9.12 0.156 116.0, 169.0 0.47
C57L/J f 125.0 23.6   6 9.65 0.189 103.0, 159.0 0.98
C57L/J m 140.0 23.7   6 9.66 0.169 93.1, 156.0 0.38
C58/J f 112.0 11.1   4 5.53 0.0992 97.2, 124.0 0.3
C58/J m 142.0 16.5   6 6.75 0.117 108.0, 150.0 0.44
CAST/EiJ f 90.0 15.5   6 6.34 0.173 68.1, 108.0 -0.86
CAST/EiJ m 103.0 14.7   5 6.58 0.142 83.3, 118.0 -0.74
DBA/2J f 109.0 14.3   12 4.14 0.131 74.7, 126.0 0.14
DBA/2J m 134.0 9.54   6 3.89 0.0713 123.0, 151.0 0.2
FVB/NJ f 122.0 15.4   6 6.29 0.127 96.8, 142.0 0.82
FVB/NJ m 138.0 23.3   6 9.5 0.168 106.0, 172.0 0.32
MOLF/EiJ f 92.4 22.3   7 8.41 0.241 57.3, 132.0 -0.74
MOLF/EiJ m 66.7 19.2   6 7.86 0.289 36.5, 85.7 -1.84
NOD/ShiLtJ f 136.0 10.9   6 4.45 0.0799 118.0, 145.0 1.56
NOD/ShiLtJ m 185.0 21.0   6 8.58 0.114 160.0, 219.0 1.74
NZB/BlNJ f 103.0 14.8   6 6.05 0.144 83.5, 126.0 -0.18
NZB/BlNJ m 117.0 6.99   6 2.85 0.0597 104.0, 125.0 -0.32
PERA/EiJ f 115.0 8.84   8 3.13 0.0768 98.8, 125.0 0.45
PERA/EiJ m 129.0 7.8   4 3.9 0.0606 119.0, 136.0 0.05
PL/J f 105.0 2.66   6 1.09 0.0254 102.0, 108.0 -0.07
PL/J m 51.1 56.3   6 23.0 1.1 -2.31
SJL/J f 99.0 14.2   6 5.81 0.144 82.2, 117.0 -0.39
SJL/J m 133.0 10.0   5 4.48 0.0751 118.0, 143.0 0.17
SM/J f 94.8 6.99   6 2.86 0.0738 87.2, 103.0 -0.61
SM/J m 138.0 12.6   6 5.13 0.0908 128.0, 163.0 0.32
SPRET/EiJ f 73.5 33.0   6 13.5 0.45 20.1, 120.0 -1.73
SPRET/EiJ m 72.5 33.2   4 16.6 0.458 34.6, 106.0 -1.66
SWR/J f 89.6 17.7   6 7.24 0.198 65.9, 104.0 -0.88
SWR/J m 113.0 7.78   6 3.18 0.0688 105.0, 124.0 -0.44


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 122.3333 8.421 138.9313 105.7354
129S1/SvImJ m 155.3333 8.421 171.9313 138.7354
A/J f 121.6667 8.421 138.2646 105.0687
A/J m 136.8333 8.421 153.4313 120.2354
AKR/J f 108.7833 8.421 125.3813 92.1854
AKR/J m 130.0 8.421 146.5979 113.4021
BALB/cByJ f 131.1333 8.421 147.7313 114.5354
BALB/cByJ m 168.8333 8.421 185.4313 152.2354
BTBR T+ Itpr3tf/J f 58.0 8.421 74.5979 41.4021
BTBR T+ Itpr3tf/J m 114.8 9.2248 132.9821 96.6179
C3H/HeJ f 106.9667 8.421 123.5646 90.3687
C3H/HeJ m 165.3333 8.421 181.9313 148.7354
C57BL/6J f 118.5583 5.9546 130.2948 106.8218
C57BL/6J m 143.1667 8.421 159.7646 126.5687
C57L/J f 125.1667 8.421 141.7646 108.5687
C57L/J m 140.1833 8.421 156.7813 123.5854
C58/J f 111.55 10.3136 131.8782 91.2218
C58/J m 141.6667 8.421 158.2646 125.0687
CAST/EiJ f 90.0167 8.421 106.6146 73.4187
CAST/EiJ m 103.18 9.2248 121.3621 84.9979
DBA/2J f 109.4583 5.9546 121.1948 97.7218
DBA/2J m 133.8333 8.421 150.4313 117.2354
FVB/NJ f 121.6333 8.421 138.2313 105.0354
FVB/NJ m 138.3333 8.421 154.9313 121.7354
MOLF/EiJ f 92.4286 7.7964 107.7953 77.0619
MOLF/EiJ m 66.6833 8.421 83.2813 50.0854
NOD/ShiLtJ f 136.3333 8.421 152.9313 119.7354
NOD/ShiLtJ m 184.6667 8.421 201.2646 168.0687
NZB/BlNJ f 102.6167 8.421 119.2146 86.0187
NZB/BlNJ m 117.0 8.421 133.5979 100.4021
PERA/EiJ f 115.1 7.2928 129.4742 100.7258
PERA/EiJ m 128.75 10.3136 149.0782 108.4218
PL/J f 104.6667 8.421 121.2646 88.0687
PL/J m 51.15 8.421 67.7479 34.5521
SJL/J f 98.95 8.421 115.5479 82.3521
SJL/J m 133.4 9.2248 151.5821 115.2179
SM/J f 94.75 8.421 111.3479 78.1521
SM/J m 138.3333 8.421 154.9313 121.7354
SPRET/EiJ f 73.4667 8.421 90.0646 56.8687
SPRET/EiJ m 72.5 10.3136 92.8282 52.1718
SWR/J f 89.6333 8.421 106.2313 73.0354
SWR/J m 113.1667 8.421 129.7646 96.5687


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 138.8333 5.9546 150.5698 127.0968
A/J both 129.25 5.9546 140.9865 117.5135
AKR/J both 119.3917 5.9546 131.1282 107.6552
BALB/cByJ both 149.9833 5.9546 161.7198 138.2468
BTBR T+ Itpr3tf/J both 86.4 6.2452 98.7093 74.0907
C3H/HeJ both 136.15 5.9546 147.8865 124.4135
C57BL/6J both 130.8625 5.1568 141.0266 120.6984
C57L/J both 132.675 5.9546 144.4115 120.9385
C58/J both 126.6083 6.6574 139.7301 113.4865
CAST/EiJ both 96.5983 6.2452 108.9077 84.289
DBA/2J both 121.6458 5.1568 131.8099 111.4817
FVB/NJ both 129.9833 5.9546 141.7198 118.2468
MOLF/EiJ both 79.556 5.738 90.8655 68.2464
NOD/ShiLtJ both 160.5 5.9546 172.2365 148.7635
NZB/BlNJ both 109.8083 5.9546 121.5448 98.0718
PERA/EiJ both 121.925 6.3158 134.3734 109.4766
PL/J both 77.9083 5.9546 89.6448 66.1718
SJL/J both 116.175 6.2452 128.4843 103.8657
SM/J both 116.5417 5.9546 128.2782 104.8052
SPRET/EiJ both 72.9833 6.6574 86.1051 59.8615
SWR/J both 101.4 5.9546 113.1365 89.6635




  GWAS USING LINEAR MIXED MODELS