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Project measure / variable:   Donahue2   thigh_muscle_area

ID, description, units MPD:17223   thigh_muscle_area   cross-sectional thigh muscle area (thigh area minus femur area), femoral mid-diaphysis   [mm2]  
Data set, strains Donahue2   inbred   10 strains     sex: both     age: 16wks
Procedure DXA
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  STRAIN COMPARISON PLOT
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Donahue2 - cross-sectional thigh muscle area (thigh area minus femur area), femoral mid-diaphysis



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested10 strains10 strains
Mean of the strain means62.9   mm2 76.8   mm2
Median of the strain means64.8   mm2 78.5   mm2
SD of the strain means± 9.12 ± 13.3
Coefficient of variation (CV)0.145 0.173
Min–max range of strain means44.8   –   76.3   mm2 48.1   –   97.0   mm2
Mean sample size per strain9.6   mice 10.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 10305.8741 10305.8741 117.788 < 0.0001
strain 9 22997.9821 2555.3313 29.2054 < 0.0001
sex:strain 9 3061.3499 340.15 3.8876 0.0002
Residuals 187 16361.5922 87.4951


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 63.5 6.35   10 2.01 0.1 55.9, 73.4 0.07
129S1/SvImJ m 69.6 15.0   15 3.87 0.216 44.0, 88.3 -0.54
BALB/cJ f 65.6 8.0   10 2.53 0.122 53.9, 77.0 0.3
BALB/cJ m 81.8 7.56   10 2.39 0.0925 71.0, 94.8 0.38
C3H/HeJ f 69.2 7.73   9 2.58 0.112 58.4, 82.5 0.69
C3H/HeJ m 78.0 10.5   10 3.31 0.134 60.9, 93.1 0.09
C57BL/6J f 64.0 6.83   8 2.42 0.107 54.2, 74.8 0.12
C57BL/6J m 88.8 13.4   12 3.86 0.151 69.8, 112.0 0.9
C58/J f 54.6 3.73   10 1.18 0.0683 49.2, 62.6 -0.91
C58/J m 72.2 7.14   10 2.26 0.0988 58.5, 83.4 -0.35
FVB/NJ f 69.7 5.28   11 1.59 0.0758 63.2, 83.2 0.75
FVB/NJ m 84.1 9.52   9 3.17 0.113 63.8, 94.5 0.55
NZB/BlNJ f 76.3 7.1   10 2.25 0.093 67.6, 92.0 1.47
NZB/BlNJ m 97.0 13.9   12 4.01 0.143 78.5, 124.0 1.52
PWK/PhJ f 44.8 6.2   12 1.79 0.138 36.1, 52.9 -1.98
PWK/PhJ m 48.1 9.76   11 2.94 0.203 34.0, 60.1 -2.16
SJL/J f 66.3 13.8   8 4.88 0.208 50.1, 92.4 0.38
SJL/J m 69.5 7.76   11 2.34 0.112 58.6, 81.8 -0.55
SWR/J f 54.8 6.24   9 2.08 0.114 46.9, 67.7 -0.89
SWR/J m 78.9 4.82   10 1.52 0.0611 72.7, 86.9 0.16


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 63.52 2.958 69.3553 57.6847
129S1/SvImJ m 69.6333 2.4152 74.3978 64.8689
BALB/cJ f 65.58 2.958 71.4153 59.7447
BALB/cJ m 81.75 2.958 87.5853 75.9147
C3H/HeJ f 69.2222 3.118 75.3731 63.0713
C3H/HeJ m 78.0 2.958 83.8353 72.1647
C57BL/6J f 64.0125 3.3071 70.5365 57.4885
C57BL/6J m 88.7583 2.7002 94.0852 83.4315
C58/J f 54.63 2.958 60.4653 48.7947
C58/J m 72.25 2.958 78.0853 66.4147
FVB/NJ f 69.6727 2.8203 75.2364 64.109
FVB/NJ m 84.1111 3.118 90.262 77.9602
NZB/BlNJ f 76.34 2.958 82.1753 70.5047
NZB/BlNJ m 96.9667 2.7002 102.2935 91.6398
PWK/PhJ f 44.8083 2.7002 50.1352 39.4815
PWK/PhJ m 48.0545 2.8203 53.6182 42.4908
SJL/J f 66.3375 3.3071 72.8615 59.8135
SJL/J m 69.5273 2.8203 75.091 63.9636
SWR/J f 54.8333 3.118 60.9842 48.6824
SWR/J m 78.86 2.958 84.6953 73.0247


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 66.5767 1.9094 70.3433 62.81
BALB/cJ both 73.665 2.0916 77.7911 69.5389
C3H/HeJ both 73.6111 2.1489 77.8503 69.3719
C57BL/6J both 76.3854 2.1347 80.5966 72.1742
C58/J both 63.44 2.0916 67.5661 59.3139
FVB/NJ both 76.8919 2.1021 81.0389 72.745
NZB/BlNJ both 86.6533 2.0025 90.6038 82.7028
PWK/PhJ both 46.4314 1.9523 50.2827 42.5801
SJL/J both 67.9324 2.1732 72.2195 63.6453
SWR/J both 66.8467 2.1489 71.0859 62.6075




  GWAS USING LINEAR MIXED MODELS