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Project measure / variable:   Hampton1   PQ

ID, description, units MPD:1707   PQ   interval between peak of P-wave to Q-wave (PQ)   [ms]  
Data set, strains Hampton1   inbred   17 strains     sex: both     age: 9-12wks
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  STRAIN COMPARISON PLOT
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Hampton1 - interval between peak of P-wave to Q-wave (PQ)



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested17 strains17 strains
Mean of the strain means21.8   ms 20.1   ms
Median of the strain means22.0   ms 21.5   ms
SD of the strain means± 2.17 ± 4.47
Coefficient of variation (CV)0.0996 0.223
Min–max range of strain means17.3   –   24.9   ms 7.20   –   25.6   ms
Mean sample size per strain7.8   mice 7.7   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 39.7484 39.7484 9.2165 0.0027
strain 15 1144.0029 76.2669 17.6841 < 0.0001
sex:strain 15 379.6596 25.3106 5.8688 < 0.0001
Residuals 216 931.5495 4.3127


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 24.9 2.26   8 0.798 0.0905 20.1, 27.5 1.43
129S1/SvImJ m 23.9 1.29   8 0.456 0.0539 22.6, 26.3 0.86
A/J f 23.2 1.36   8 0.481 0.0587 20.7, 25.0 0.65
A/J m 22.1 1.18   7 0.445 0.0533 20.6, 24.1 0.46
AKR/J f 22.0 2.34   8 0.827 0.106 17.4, 24.5 0.09
AKR/J m 21.6 1.84   8 0.651 0.0854 18.1, 23.9 0.34
BALB/cJ f 21.9 1.49   7 0.564 0.0683 19.3, 23.4 0.05
BALB/cJ m 20.7 2.98   8 1.05 0.144 15.3, 24.2 0.14
BTBR T+ Itpr3tf/J f 22.2 2.36   8 0.833 0.106 19.0, 25.0 0.19
BTBR T+ Itpr3tf/J m 25.6 1.28   8 0.453 0.0502 24.3, 28.1 1.24
C3H/HeJ f 17.3 3.87   7 1.46 0.224 10.7, 22.8 -2.07
C3H/HeJ m 19.3 1.71   8 0.604 0.0885 16.0, 21.2 -0.17
C57BL/6J f 21.1 1.14   8 0.404 0.0542 19.0, 22.4 -0.32
C57BL/6J m 22.4 2.58   8 0.914 0.115 18.2, 24.6 0.52
CAST/EiJ f 19.0 1.13   8 0.4 0.0595 17.1, 20.1 -1.29
CAST/EiJ m 16.8 2.16   8 0.764 0.129 13.4, 19.6 -0.73
CBA/J f 19.3 2.64   8 0.933 0.136 13.8, 21.9 -1.15
CBA/J m 21.5 1.29   8 0.455 0.0599 19.5, 23.1 0.32
DBA/2J f 21.8 0.737   6 0.301 0.0339 20.5, 22.4 0.0
DBA/2J m 7.2 0.0   1   0.0 0.0 7.2, 7.2 -2.88
FVB/NJ f 18.7 2.56   7 0.968 0.137 14.8, 22.3 -1.42
FVB/NJ m 17.0 2.33   8 0.822 0.137 11.8, 19.8 -0.69
LP/J f 22.6 1.49   8 0.526 0.0658 20.1, 24.6 0.37
LP/J m 22.8 1.92   8 0.678 0.0841 20.3, 25.4 0.61
NOD/ShiLtJ f 22.9 1.84   8 0.652 0.0805 19.2, 24.6 0.51
NOD/ShiLtJ m 21.4 0.389   8 0.138 0.0181 21.0, 22.1 0.3
NZB/BlNJ f 24.8 1.19   8 0.422 0.0481 22.7, 26.1 1.38
NZB/BlNJ m 21.0 3.3   7 1.25 0.157 15.7, 24.1 0.21
PL/J f 23.9 2.39   8 0.845 0.0999 19.7, 28.0 0.97
PL/J m 22.1 1.18   8 0.418 0.0535 19.8, 23.4 0.46
SJL/J f 23.7 2.36   8 0.835 0.0998 19.5, 26.0 0.88
SJL/J m 22.8 1.01   8 0.358 0.0443 21.4, 24.2 0.61
SWR/J f 21.2 2.01   8 0.71 0.0945 18.3, 23.3 -0.27
SWR/J m 12.9 4.01   5 1.79 0.31 8.3, 17.6 -1.6


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 24.9375 0.7342 26.3847 23.4903
129S1/SvImJ m 23.9125 0.7342 25.3597 22.4653
A/J f 23.1625 0.7342 24.6097 21.7153
A/J m 22.1 0.7849 23.6471 20.5529
AKR/J f 22.0 0.7342 23.4472 20.5528
AKR/J m 21.5875 0.7342 23.0347 20.1403
BALB/cJ f 21.8714 0.7849 23.4185 20.3243
BALB/cJ m 20.725 0.7342 22.1722 19.2778
BTBR T+ Itpr3tf/J f 22.2375 0.7342 23.6847 20.7903
BTBR T+ Itpr3tf/J m 25.55 0.7342 26.9972 24.1028
C3H/HeJ f 17.2571 0.7849 18.8042 15.7101
C3H/HeJ m 19.3125 0.7342 20.7597 17.8653
C57BL/6J f 21.0875 0.7342 22.5347 19.6403
C57BL/6J m 22.425 0.7342 23.8722 20.9778
CAST/EiJ f 19.0 0.7342 20.4472 17.5528
CAST/EiJ m 16.75 0.7342 18.1972 15.3028
CBA/J f 19.3375 0.7342 20.7847 17.8903
CBA/J m 21.475 0.7342 22.9222 20.0278
FVB/NJ f 18.6714 0.7849 20.2185 17.1243
FVB/NJ m 17.0125 0.7342 18.4597 15.5653
LP/J f 22.625 0.7342 24.0722 21.1778
LP/J m 22.8 0.7342 24.2472 21.3528
NOD/ShiLtJ f 22.8875 0.7342 24.3347 21.4403
NOD/ShiLtJ m 21.4375 0.7342 22.8847 19.9903
NZB/BlNJ f 24.8125 0.7342 26.2597 23.3653
NZB/BlNJ m 21.0286 0.7849 22.5757 19.4815
PL/J f 23.925 0.7342 25.3722 22.4778
PL/J m 22.075 0.7342 23.5222 20.6278
SJL/J f 23.675 0.7342 25.1222 22.2278
SJL/J m 22.8375 0.7342 24.2847 21.3903
SWR/J f 21.2375 0.7342 22.6847 19.7903
SWR/J m 12.94 0.9287 14.7705 11.1095


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 24.425 0.5192 25.4483 23.4017
A/J both 22.6313 0.5374 23.6905 21.572
AKR/J both 21.7937 0.5192 22.8171 20.7704
BALB/cJ both 21.2982 0.5374 22.3574 20.239
BTBR T+ Itpr3tf/J both 23.8938 0.5192 24.9171 22.8704
C3H/HeJ both 18.2848 0.5374 19.344 17.2256
C57BL/6J both 21.7563 0.5192 22.7796 20.7329
CAST/EiJ both 17.875 0.5192 18.8983 16.8517
CBA/J both 20.4063 0.5192 21.4296 19.3829
FVB/NJ both 17.842 0.5374 18.9012 16.7827
LP/J both 22.7125 0.5192 23.7358 21.6892
NOD/ShiLtJ both 22.1625 0.5192 23.1858 21.1392
NZB/BlNJ both 22.9205 0.5374 23.9798 21.8613
PL/J both 23.0 0.5192 24.0233 21.9767
SJL/J both 23.2563 0.5192 24.2796 22.2329
SWR/J both 17.0888 0.592 18.2555 15.922




  GWAS USING LINEAR MIXED MODELS