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Project measure / variable:   Crabbe3   ARR1_improvement

ID, description, units MPD:15831   ARR1_improvement   accelerating rotarod (ARR1) acquisition trial average of last 3 trials minus average of first 3 trials (20 rpm/min)   [s]  
Data set, strains Crabbe3   inbred   8 strains     sex: both     age: 9-17wks
Procedure rotarod
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  STRAIN COMPARISON PLOT
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Crabbe3 - accelerating rotarod (ARR1) acquisition trial average of last 3 trials minus average of first 3 trials (20 rpm/min)



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means17.3   s 11.3   s
Median of the strain means11.2   s 6.56   s
SD of the strain means± 17.8 ± 10.5
Coefficient of variation (CV)1.03 0.932
Min–max range of strain means4.31   –   58.7   s -0.0833   –   28.1   s
Mean sample size per strain5.8   mice 5.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 594.6386 594.6386 7.2926 0.0086
strain 7 11696.3142 1670.902 20.4918 < 0.0001
sex:strain 7 1756.0893 250.8699 3.0766 0.0068
Residuals 73 5952.4296 81.5401


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 15.7 5.37   6 2.19 0.342 9.63, 24.6 -0.09
129S1/SvImJ m 24.2 6.48   6 2.64 0.268 13.6, 30.8 1.23
A/J f 4.31 8.78   6 3.59 2.04 -6.17, 19.0 -0.73
A/J m -0.0833 7.47   6 3.05 -89.6 -10.4, 5.7 -1.08
BALB/cByJ f 12.4 11.0   6 4.48 0.884 2.07, 27.0 -0.28
BALB/cByJ m 5.32 9.32   4 4.66 1.75 -5.17, 14.0 -0.57
BTBR T+ Itpr3tf/J f 58.7 14.1   4 7.04 0.24 38.1, 69.7 2.32
BTBR T+ Itpr3tf/J m 28.1 12.5   3 7.19 0.444 13.8, 36.8 1.6
C3H/HeJ f 10.1 10.1   6 4.11 0.997 -0.633, 23.6 -0.41
C3H/HeJ m 4.9 8.08   6 3.3 1.65 -4.23, 17.6 -0.61
C57BL/6J f 23.5 7.97   6 3.25 0.339 16.1, 35.3 0.35
C57BL/6J m 17.0 11.3   6 4.63 0.667 0.233, 27.4 0.55
DBA/2J f 4.4 8.88   6 3.62 2.01 -6.37, 17.7 -0.73
DBA/2J m 2.86 8.25   6 3.37 2.88 -4.87, 16.2 -0.8
FVB/NJ f 9.56 10.0   6 4.1 1.05 -2.97, 22.9 -0.44
FVB/NJ m 7.81 5.17   6 2.11 0.661 3.07, 16.4 -0.33


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 15.705 3.6865 23.0521 8.3579
129S1/SvImJ m 24.1833 3.6865 31.5304 16.8362
A/J f 4.31 3.6865 11.6571 -3.0371
A/J m -0.0833 3.6865 7.2638 -7.4304
BALB/cByJ f 12.4233 3.6865 19.7704 5.0762
BALB/cByJ m 5.3243 4.515 14.3226 -3.6741
BTBR T+ Itpr3tf/J f 58.725 4.515 67.7233 49.7267
BTBR T+ Itpr3tf/J m 28.0667 5.2134 38.4571 17.6763
C3H/HeJ f 10.0828 3.6865 17.4299 2.7357
C3H/HeJ m 4.9005 3.6865 12.2476 -2.4466
C57BL/6J f 23.4667 3.6865 30.8138 16.1196
C57BL/6J m 17.0088 3.6865 24.3559 9.6617
DBA/2J f 4.405 3.6865 11.7521 -2.9421
DBA/2J m 2.8612 3.6865 10.2083 -4.4859
FVB/NJ f 9.56 3.6865 16.9071 2.2129
FVB/NJ m 7.8117 3.6865 15.1588 0.4646


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 19.9442 2.6067 25.1394 14.749
A/J both 2.1133 2.6067 7.3085 -3.0819
BALB/cByJ both 8.8738 2.9144 14.6822 3.0654
BTBR T+ Itpr3tf/J both 43.3958 3.4484 50.2684 36.5232
C3H/HeJ both 7.4917 2.6067 12.6869 2.2965
C57BL/6J both 20.2378 2.6067 25.4329 15.0426
DBA/2J both 3.6331 2.6067 8.8283 -1.5621
FVB/NJ both 8.6858 2.6067 13.881 3.4906




  GWAS USING LINEAR MIXED MODELS