Project measure / variable:   Jaxwest1   BMC_femurR

ID, description, units MPD:15133   BMC_femurR   bone mineral content (BMC) of right femur   [g]  
Data set, strains Jaxwest1   inbred   7 strains     sex: both     age: 11-13wks
Procedure DXA
Ontology mappings

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  STRAIN COMPARISON PLOT
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Jaxwest1 - bone mineral content (BMC) of right femur



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested7 strains7 strains
Mean of the strain means0.0280   g 0.0327   g
Median of the strain means0.0278   g 0.0331   g
SD of the strain means± 0.00374 ± 0.00480
Coefficient of variation (CV)0.133 0.147
Min–max range of strain means0.0221   –   0.0330   g 0.0257   –   0.0409   g
Mean sample size per strain7.9   mice 7.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.0006 0.0006 52.9023 < 0.0001
strain 6 0.0015 0.0003 22.1989 < 0.0001
sex:strain 6 0.0002 0.0 3.0929 0.0082
Residuals 96 0.0011 0.0


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 0.0276 0.00346   8 0.00122 0.125 0.023, 0.0326 -0.11
129S1/SvImJ m 0.0331 0.00487   8 0.00172 0.147 0.026, 0.0425 0.09
A/J f 0.0221 0.00228   8 0.000807 0.103 0.0187, 0.0257 -1.58
A/J m 0.0257 0.00221   8 0.000782 0.086 0.0229, 0.0284 -1.45
BALB/cJ f 0.033 0.00365   8 0.00129 0.111 0.028, 0.038 1.33
BALB/cJ m 0.0409 0.00581   8 0.00205 0.142 0.0337, 0.0505 1.72
C57BL/6J f 0.0247 0.00287   8 0.00102 0.116 0.0217, 0.0293 -0.89
C57BL/6J m 0.0338 0.00405   8 0.00143 0.12 0.0281, 0.0392 0.24
DBA/2J f 0.0278 0.00336   7 0.00127 0.121 0.0241, 0.0334 -0.06
DBA/2J m 0.0284 0.00333   7 0.00126 0.117 0.0246, 0.033 -0.89
NOD/ShiLtJ f 0.0298 0.00314   8 0.00111 0.105 0.0259, 0.0339 0.48
NOD/ShiLtJ m 0.0326 0.00161   8 0.000571 0.0496 0.0307, 0.0348 -0.01
SJL/J f 0.0311 0.00246   8 0.000869 0.079 0.0281, 0.0343 0.83
SJL/J m 0.0341 0.00172   8 0.000607 0.0504 0.0319, 0.0373 0.3


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 0.0276 0.0012 0.03 0.0252
129S1/SvImJ m 0.0331 0.0012 0.0355 0.0308
A/J f 0.0221 0.0012 0.0245 0.0198
A/J m 0.0257 0.0012 0.0281 0.0233
BALB/cJ f 0.033 0.0012 0.0354 0.0306
BALB/cJ m 0.0409 0.0012 0.0433 0.0385
C57BL/6J f 0.0247 0.0012 0.0271 0.0223
C57BL/6J m 0.0338 0.0012 0.0362 0.0315
DBA/2J f 0.0278 0.0013 0.0303 0.0252
DBA/2J m 0.0284 0.0013 0.0309 0.0258
NOD/ShiLtJ f 0.0298 0.0012 0.0322 0.0274
NOD/ShiLtJ m 0.0326 0.0012 0.0349 0.0302
SJL/J f 0.0311 0.0012 0.0335 0.0287
SJL/J m 0.0341 0.0012 0.0365 0.0317


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 0.0304 0.0008 0.0321 0.0287
A/J both 0.0239 0.0008 0.0256 0.0222
BALB/cJ both 0.0369 0.0008 0.0386 0.0352
C57BL/6J both 0.0293 0.0008 0.031 0.0276
DBA/2J both 0.0281 0.0009 0.0299 0.0263
NOD/ShiLtJ both 0.0312 0.0008 0.0329 0.0295
SJL/J both 0.0326 0.0008 0.0343 0.0309




  GWAS USING LINEAR MIXED MODELS