Project measure / variable:   Justice2   RDW

ID, description, units MPD:13213   RDW   RBC corpuscular distribution width (RDW)   [%]  
Data set, strains Justice2   inbred   16 strains     sex: both     age: 12-16wks
Procedure complete blood count
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  STRAIN COMPARISON PLOT
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Justice2 - RBC corpuscular distribution width (RDW)



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested16 strains16 strains
Mean of the strain means17.6   % 18.0   %
Median of the strain means17.5   % 17.4   %
SD of the strain means± 1.02 ± 1.72
Coefficient of variation (CV)0.0579 0.0954
Min–max range of strain means16.0   –   20.2   % 16.3   –   23.0   %
Mean sample size per strain12.6   mice 12.4   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 18.1641 18.1641 17.3106 < 0.0001
strain 15 566.4202 37.7613 35.9869 < 0.0001
sex:strain 15 71.4747 4.765 4.5411 < 0.0001
Residuals 365 382.9975 1.0493


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 18.3 0.933   15 0.241 0.051 16.9, 20.5 0.72
129S1/SvImJ m 18.7 0.992   15 0.256 0.0529 17.3, 20.5 0.39
129S6/SvEvTac f 18.1 0.5   10 0.158 0.0276 17.4, 18.7 0.52
129S6/SvEvTac m 19.0 1.38   10 0.436 0.0726 17.3, 21.5 0.57
A/J f 17.9 0.817   10 0.258 0.0457 16.2, 19.0 0.33
A/J m 17.4 0.997   8 0.353 0.0571 16.3, 18.7 -0.36
BALB/cByJ f 17.2 0.851   15 0.22 0.0495 16.1, 19.1 -0.36
BALB/cByJ m 17.5 0.631   15 0.163 0.0361 16.7, 19.2 -0.31
BALB/cJ f 16.0 0.805   10 0.254 0.0503 14.9, 17.5 -1.54
BALB/cJ m 16.8 0.701   9 0.234 0.0417 15.7, 17.7 -0.71
BTBR T+ Itpr3tf/J f 17.1 0.807   10 0.255 0.0473 15.9, 18.2 -0.46
BTBR T+ Itpr3tf/J m 16.6 0.628   10 0.198 0.0379 15.7, 17.9 -0.83
C3HeB/FeJ f 17.2 1.1   15 0.285 0.0642 15.4, 19.1 -0.36
C3HeB/FeJ m 17.0 0.585   15 0.151 0.0345 15.7, 18.1 -0.6
C3H/HeJ f 16.6 0.87   10 0.275 0.0522 15.6, 18.3 -0.95
C3H/HeJ m 17.3 0.823   10 0.26 0.0475 16.0, 18.3 -0.42
C57BL/10J f 17.7 0.765   13 0.212 0.0432 16.8, 19.2 0.13
C57BL/10J m 17.7 0.943   15 0.243 0.0533 16.3, 19.5 -0.19
C57BL/6J f 17.5 0.694   15 0.179 0.0397 16.6, 19.0 -0.07
C57BL/6J m 18.8 1.22   14 0.326 0.0648 16.5, 20.4 0.45
CAST/EiJ f 20.2 1.33   9 0.442 0.0655 18.6, 22.8 2.59
CAST/EiJ m 23.0 2.42   9 0.806 0.105 20.0, 28.3 2.89
CBA/CaJ f 17.5 1.07   14 0.286 0.0611 16.3, 19.8 -0.07
CBA/CaJ m 16.5 0.716   14 0.191 0.0435 15.4, 17.7 -0.89
CBA/J f 16.3 0.822   10 0.26 0.0505 15.3, 18.2 -1.25
CBA/J m 16.3 1.04   9 0.348 0.0642 14.2, 17.5 -1.0
DBA/2J f 18.4 0.82   15 0.212 0.0447 16.9, 20.4 0.82
DBA/2J m 19.5 1.21   14 0.323 0.0621 18.0, 21.7 0.86
FVB/NJ f 16.7 0.64   15 0.165 0.0383 15.9, 18.1 -0.85
FVB/NJ m 16.7 0.577   15 0.149 0.0346 15.7, 17.5 -0.77
SJL/J f 18.4 1.24   15 0.319 0.0672 16.0, 20.6 0.82
SJL/J m 19.6 2.0   14 0.535 0.102 16.8, 24.0 0.92


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 18.3133 0.2645 18.8334 17.7932
129S1/SvImJ m 18.74 0.2645 19.2601 18.2199
129S6/SvEvTac f 18.11 0.3239 18.747 17.473
129S6/SvEvTac m 18.99 0.3239 19.627 18.353
A/J f 17.86 0.3239 18.497 17.223
A/J m 17.45 0.3622 18.1622 16.7378
BALB/cByJ f 17.1933 0.2645 17.7134 16.6732
BALB/cByJ m 17.46 0.2645 17.9801 16.9399
BALB/cJ f 15.99 0.3239 16.627 15.353
BALB/cJ m 16.8222 0.3415 17.4937 16.1508
BTBR T+ Itpr3tf/J f 17.05 0.3239 17.687 16.413
BTBR T+ Itpr3tf/J m 16.56 0.3239 17.197 15.923
C3HeB/FeJ f 17.2 0.2645 17.7201 16.6799
C3HeB/FeJ m 16.9533 0.2645 17.4734 16.4332
C3H/HeJ f 16.65 0.3239 17.287 16.013
C3H/HeJ m 17.33 0.3239 17.967 16.693
C57BL/10J f 17.7231 0.2841 18.2818 17.1644
C57BL/10J m 17.68 0.2645 18.2001 17.1599
C57BL/6J f 17.48 0.2645 18.0001 16.9599
C57BL/6J m 18.8 0.2738 19.3384 18.2616
CAST/EiJ f 20.2444 0.3415 20.9159 19.573
CAST/EiJ m 23.0444 0.3415 23.7159 22.373
CBA/CaJ f 17.5143 0.2738 18.0527 16.9759
CBA/CaJ m 16.4714 0.2738 17.0098 15.9331
CBA/J f 16.28 0.3239 16.917 15.643
CBA/J m 16.2556 0.3415 16.927 15.5841
DBA/2J f 18.36 0.2645 18.8801 17.8399
DBA/2J m 19.4786 0.2738 20.0169 18.9402
FVB/NJ f 16.6933 0.2645 17.2134 16.1732
FVB/NJ m 16.6867 0.2645 17.2068 16.1666
SJL/J f 18.4 0.2645 18.9201 17.8799
SJL/J m 19.6429 0.2738 20.1812 19.1045


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 18.5267 0.187 18.8944 18.1589
129S6/SvEvTac both 18.55 0.2291 19.0004 18.0996
A/J both 17.655 0.2429 18.1328 17.1772
BALB/cByJ both 17.3267 0.187 17.6944 16.9589
BALB/cJ both 16.4061 0.2353 16.8689 15.9433
BTBR T+ Itpr3tf/J both 16.805 0.2291 17.2554 16.3546
C3HeB/FeJ both 17.0767 0.187 17.4444 16.7089
C3H/HeJ both 16.99 0.2291 17.4404 16.5396
C57BL/10J both 17.7015 0.1941 18.0832 17.3199
C57BL/6J both 18.14 0.1903 18.5143 17.7657
CAST/EiJ both 21.6444 0.2414 22.1192 21.1696
CBA/CaJ both 16.9929 0.1936 17.3735 16.6122
CBA/J both 16.2678 0.2353 16.7306 15.805
DBA/2J both 18.9193 0.1903 19.2936 18.545
FVB/NJ both 16.69 0.187 17.0578 16.3222
SJL/J both 19.0214 0.1903 19.3957 18.6471




  GWAS USING LINEAR MIXED MODELS