MPD: Project measure / variable: Donahue1 lower

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Donahue1 - length of lower jaw

Measure Summary	Female	Male
Number of strains tested	29 strains	29 strains
Mean of the strain means	10.3 mm	10.5 mm
Median of the strain means	10.4 mm	10.4 mm
SD of the strain means	± 0.770	± 0.793
Coefficient of variation (CV)	0.0746	0.0756
Min–max range of strain means	8.85 – 11.5 mm	8.96 – 12.0 mm
Mean sample size per strain	9.5 mice	9.3 mice

ANOVA, Q-Q NORMALITY ASSESSMENT

ANOVA summary

Factor	DF	Sum of squares	Mean sum of squares	F value	p value (Pr>F)
sex	1	4.4	4.4	79.9408	< 0.0001
strain	28	306.8952	10.9605	199.136	< 0.0001
sex:strain	28	3.9591	0.1414	2.569	< 0.0001
Residuals	485	26.6946	0.055

Q-Q normality assessment based on residuals

STRAIN MEANS (UNADJUSTED)

Strain	Sex	Mean	SD	N mice	SEM	CV	Min, Max	Z score
129S1/SvImJ	f	11.4	0.267	10	0.0843	0.0234	10.9, 11.8	1.4
129S1/SvImJ	m	11.8	0.231	10	0.0731	0.0196	11.5, 12.1	1.66
A/J	f	10.9	0.294	10	0.0929	0.0269	10.4, 11.5	0.75
A/J	m	10.9	0.29	8	0.103	0.0266	10.2, 11.1	0.52
AKR/J	f	10.9	0.149	10	0.0473	0.0137	10.7, 11.1	0.75
AKR/J	m	10.7	0.124	9	0.0412	0.0115	10.6, 11.0	0.27
BALB/cJ	f	11.0	0.171	10	0.0542	0.0155	10.8, 11.3	0.88
BALB/cJ	m	11.5	0.189	10	0.0597	0.0164	11.2, 11.9	1.28
BTBR T⁺ Itpr3^tf/J	f	11.5	0.983	9	0.328	0.0857	9.0, 12.1	1.53
BTBR T⁺ Itpr3^tf/J	m	12.0	0.256	10	0.0809	0.0213	11.7, 12.4	1.91
BUB/BnJ	f	10.5	0.173	9	0.0577	0.0165	10.2, 10.8	0.23
BUB/BnJ	m	10.6	0.146	8	0.0515	0.0137	10.5, 10.9	0.14
C3H/HeJ	f	10.8	0.226	10	0.0716	0.021	10.5, 11.1	0.62
C3H/HeJ	m	10.9	0.254	10	0.0803	0.0233	10.4, 11.2	0.52
C57BL/6J	f	11.3	0.169	10	0.0533	0.015	11.0, 11.6	1.27
C57BL/6J	m	11.3	0.164	10	0.0517	0.0145	10.9, 11.5	1.03
C57L/J	f	10.9	0.227	10	0.0719	0.0208	10.5, 11.4	0.75
C57L/J	m	11.2	0.141	10	0.0447	0.0126	11.0, 11.4	0.9
C58/J	f	10.3	0.258	10	0.0815	0.0251	9.84, 10.6	-0.03
C58/J	m	10.4	0.146	8	0.0515	0.014	10.2, 10.6	-0.11
CAST/EiJ	f	9.16	0.254	9	0.0845	0.0277	8.79, 9.68	-1.51
CAST/EiJ	m	9.19	0.131	9	0.0436	0.0142	9.08, 9.47	-1.64
CZECHII/EiJ	f	9.3	0.143	8	0.0507	0.0154	9.12, 9.55	-1.33
CZECHII/EiJ	m	9.55	0.279	9	0.093	0.0292	9.23, 9.93	-1.18
DBA/2J	f	10.1	0.139	10	0.0441	0.0138	9.87, 10.3	-0.29
DBA/2J	m	10.3	0.179	9	0.0595	0.0174	9.88, 10.5	-0.24
FVB/NJ	f	10.3	0.207	10	0.0656	0.0202	9.97, 10.7	-0.03
FVB/NJ	m	10.4	0.149	10	0.0471	0.0143	10.1, 10.6	-0.11
JF1/MsJ	f	9.75	0.281	9	0.0936	0.0288	9.43, 10.2	-0.75
JF1/MsJ	m	9.81	0.214	9	0.0713	0.0218	9.51, 10.2	-0.85
MOLF/EiJ	f	8.85	0.164	10	0.052	0.0186	8.67, 9.15	-1.91
MOLF/EiJ	m	8.96	0.198	7	0.0749	0.0221	8.62, 9.23	-1.93
MSM/MsJ	f	8.91	0.249	8	0.0879	0.0279	8.62, 9.23	-1.84
MSM/MsJ	m	9.04	0.0583	7	0.022	0.00644	8.97, 9.13	-1.83
NOD/ShiLtJ	f	10.4	0.215	10	0.068	0.0206	10.1, 10.7	0.1
NOD/ShiLtJ	m	11.0	0.267	10	0.0846	0.0244	10.7, 11.6	0.65
NZB/BlNJ	f	11.5	0.19	10	0.06	0.0166	11.2, 11.8	1.53
NZB/BlNJ	m	11.3	0.184	10	0.0581	0.0162	10.9, 11.5	1.03
NZW/LacJ	f	11.1	0.158	10	0.0499	0.0143	10.8, 11.3	1.01
NZW/LacJ	m	11.2	0.126	10	0.04	0.0113	11.0, 11.4	0.9
PERA/EiJ	f	10.2	0.16	8	0.0567	0.0158	9.8, 10.3	-0.16
PERA/EiJ	m	10.4	0.149	10	0.0473	0.0144	10.2, 10.6	-0.11
PL/J	f	10.5	0.165	10	0.0521	0.0157	10.3, 10.8	0.23
PL/J	m	10.6	0.142	9	0.0475	0.0135	10.4, 10.8	0.14
PWK/PhJ	f	9.83	0.154	7	0.0583	0.0157	9.6, 9.99	-0.64
PWK/PhJ	m	10.2	0.363	9	0.121	0.0356	9.32, 10.6	-0.36
SEA/GnJ	f	10.7	0.16	11	0.0483	0.0149	10.4, 11.0	0.49
SEA/GnJ	m	10.9	0.225	10	0.0712	0.0206	10.6, 11.3	0.52
SJL/J	f	10.4	0.106	10	0.0335	0.0102	10.2, 10.6	0.1
SJL/J	m	10.4	0.166	10	0.0526	0.016	10.2, 10.7	-0.11
SM/J	f	9.21	0.228	9	0.0759	0.0247	8.85, 9.59	-1.45
SM/J	m	9.57	0.122	10	0.0385	0.0127	9.4, 9.73	-1.16
SPRET/EiJ	f	9.71	0.325	7	0.123	0.0335	9.39, 10.2	-0.8
SPRET/EiJ	m	9.79	0.132	10	0.0418	0.0135	9.52, 9.96	-0.88
SWR/J	f	10.3	0.103	10	0.0327	0.01	10.1, 10.4	-0.03
SWR/J	m	10.4	0.152	10	0.0482	0.0147	10.2, 10.7	-0.11
WSB/EiJ	f	9.69	0.211	10	0.0666	0.0218	9.29, 10.0	-0.82
WSB/EiJ	m	9.82	0.145	8	0.0514	0.0148	9.57, 9.98	-0.84

LEAST SQUARES MEANS (MODEL-ADJUSTED)

Strain	Sex	Mean	SEM	UpperCL	LowerCL
129S1/SvImJ	f	11.4	0.0742	11.5458	11.2542
129S1/SvImJ	m	11.77	0.0742	11.9158	11.6242
A/J	f	10.92	0.0742	11.0658	10.7742
A/J	m	10.8875	0.0829	11.0505	10.7245
AKR/J	f	10.87	0.0742	11.0158	10.7242
AKR/J	m	10.7444	0.0782	10.8981	10.5908
BALB/cJ	f	11.04	0.0742	11.1858	10.8942
BALB/cJ	m	11.53	0.0742	11.6758	11.3842
BTBR T⁺ Itpr3^tf/J	f	11.4778	0.0782	11.6314	11.3241
BTBR T⁺ Itpr3^tf/J	m	12.01	0.0742	12.1558	11.8642
BUB/BnJ	f	10.4667	0.0782	10.6203	10.313
BUB/BnJ	m	10.6125	0.0829	10.7755	10.4495
C3H/HeJ	f	10.77	0.0742	10.9158	10.6242
C3H/HeJ	m	10.9	0.0742	11.0458	10.7542
C57BL/6J	f	11.28	0.0742	11.4258	11.1342
C57BL/6J	m	11.27	0.0742	11.4158	11.1242
C57L/J	f	10.95	0.0742	11.0958	10.8042
C57L/J	m	11.2	0.0742	11.3458	11.0542
C58/J	f	10.253	0.0742	10.3988	10.1072
C58/J	m	10.3875	0.0829	10.5505	10.2245
CAST/EiJ	f	9.1644	0.0782	9.3181	9.0108
CAST/EiJ	m	9.1933	0.0782	9.347	9.0397
CZECHII/EiJ	f	9.2988	0.0829	9.4617	9.1358
CZECHII/EiJ	m	9.5511	0.0782	9.7048	9.3975
DBA/2J	f	10.087	0.0742	10.2328	9.9412
DBA/2J	m	10.2644	0.0782	10.4181	10.1108
FVB/NJ	f	10.287	0.0742	10.4328	10.1412
FVB/NJ	m	10.4	0.0742	10.5458	10.2542
JF1/MsJ	f	9.7456	0.0782	9.8992	9.5919
JF1/MsJ	m	9.8067	0.0782	9.9603	9.653
MOLF/EiJ	f	8.851	0.0742	8.9968	8.7052
MOLF/EiJ	m	8.9571	0.0887	9.1314	8.7829
MSM/MsJ	f	8.9062	0.0829	9.0692	8.7433
MSM/MsJ	m	9.0443	0.0887	9.2185	8.8701
NOD/ShiLtJ	f	10.42	0.0742	10.5658	10.2742
NOD/ShiLtJ	m	10.96	0.0742	11.1058	10.8142
NZB/BlNJ	f	11.46	0.0742	11.6058	11.3142
NZB/BlNJ	m	11.34	0.0742	11.4858	11.1942
NZW/LacJ	f	11.06	0.0742	11.2058	10.9142
NZW/LacJ	m	11.24	0.0742	11.3858	11.0942
PERA/EiJ	f	10.15	0.0829	10.313	9.987
PERA/EiJ	m	10.37	0.0742	10.5158	10.2242
PL/J	f	10.46	0.0742	10.6058	10.3142
PL/J	m	10.5556	0.0782	10.7092	10.4019
PWK/PhJ	f	9.8271	0.0887	10.0014	9.6529
PWK/PhJ	m	10.1911	0.0782	10.3448	10.0375
SEA/GnJ	f	10.7182	0.0707	10.8572	10.5792
SEA/GnJ	m	10.92	0.0742	11.0658	10.7742
SJL/J	f	10.37	0.0742	10.5158	10.2242
SJL/J	m	10.41	0.0742	10.5558	10.2642
SM/J	f	9.2089	0.0782	9.3625	9.0552
SM/J	m	9.571	0.0742	9.7168	9.4252
SPRET/EiJ	f	9.7129	0.0887	9.8871	9.5386
SPRET/EiJ	m	9.793	0.0742	9.9388	9.6472
SWR/J	f	10.28	0.0742	10.4258	10.1342
SWR/J	m	10.39	0.0742	10.5358	10.2442
WSB/EiJ	f	9.685	0.0742	9.8308	9.5392
WSB/EiJ	m	9.8225	0.0829	9.9855	9.6595

LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED

Strain	Sex	Mean	SEM	UpperCL	LowerCL
129S1/SvImJ	both	11.585	0.0525	11.6881	11.4819
A/J	both	10.9038	0.0556	11.0131	10.7944
AKR/J	both	10.8072	0.0539	10.9131	10.7013
BALB/cJ	both	11.285	0.0525	11.3881	11.1819
BTBR T⁺ Itpr3^tf/J	both	11.7439	0.0539	11.8498	11.638
BUB/BnJ	both	10.5396	0.057	10.6516	10.4276
C3H/HeJ	both	10.835	0.0525	10.9381	10.7319
C57BL/6J	both	11.275	0.0525	11.3781	11.1719
C57L/J	both	11.075	0.0525	11.1781	10.9719
C58/J	both	10.3202	0.0556	10.4296	10.2109
CAST/EiJ	both	9.1789	0.0553	9.2875	9.0702
CZECHII/EiJ	both	9.4249	0.057	9.5369	9.3129
DBA/2J	both	10.1757	0.0539	10.2816	10.0698
FVB/NJ	both	10.3435	0.0525	10.4466	10.2404
JF1/MsJ	both	9.7761	0.0553	9.8848	9.6675
MOLF/EiJ	both	8.9041	0.0578	9.0177	8.7905
MSM/MsJ	both	8.9753	0.0607	9.0946	8.856
NOD/ShiLtJ	both	10.69	0.0525	10.7931	10.5869
NZB/BlNJ	both	11.4	0.0525	11.5031	11.2969
NZW/LacJ	both	11.15	0.0525	11.2531	11.0469
PERA/EiJ	both	10.26	0.0556	10.3693	10.1507
PL/J	both	10.5078	0.0539	10.6137	10.4019
PWK/PhJ	both	10.0091	0.0591	10.1253	9.893
SEA/GnJ	both	10.8191	0.0513	10.9198	10.7184
SJL/J	both	10.39	0.0525	10.4931	10.2869
SM/J	both	9.3899	0.0539	9.4958	9.284
SPRET/EiJ	both	9.7529	0.0578	9.8665	9.6393
SWR/J	both	10.335	0.0525	10.4381	10.2319
WSB/EiJ	both	9.7538	0.0556	9.8631	9.6444

INDIVIDUAL ANIMAL VALUES

Click here to view individual animal values

GWAS USING LINEAR MIXED MODELS

ID, description, units	MPD:11524 lower_jaw length of lower jaw [mm]
Data set, strains	Donahue1 inbred w/CC7 29 strains sex: both age: 15-16wks
Procedure	DXA
Ontology mappings	MA:0000316 cranium MP:0000428 abnormal craniofacial morphology MP:0002116 abnormal craniofacial bone morphology VT:0000458 mandible morphology trait