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Project measure / variable:   Bennett4   TMAO_post_HFHS

ID, description, units MPD:114768   TMAO_post_HFHS   plasma trimethylamine N-oxide (TMAO) amount, post-diet   [µM]  HFHS group  
various diets 2 study
Data set, strains Bennett4   CC   22 strains     sex: f     age: 17-20wks
Procedure biomarker quantification
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  STRAIN COMPARISON PLOT
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Bennett4 - plasma trimethylamine N-oxide (TMAO) amount, post-diet HFHS group



  MEASURE SUMMARY
Measure Summary Female
Number of strains tested22 strains
Mean of the strain means3.1775   µM
Median of the strain means2.64   µM
SD of the strain means± 1.5512
Coefficient of variation (CV)0.4882
Min–max range of strain means0.96667   –   6.3333   µM
Mean sample size per strain4.5   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 21 209.7062 9.986 2.4366 0.0026
Residuals 76 311.4788 4.0984


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
CC001/Unc f 2.6 1.2629   5 0.5648 0.4857 1.6, 4.8 -0.37
CC002/Unc f 3.26 1.0286   5 0.46 0.3155 2.0, 4.6 0.05
CC004/TauUnc f 2.06 0.65803   5 0.29428 0.3194 1.3, 3.0 -0.72
CC006/TauUnc f 3.55 1.4708   4 0.73541 0.4143 2.3, 5.6 0.24
CC008/GeniUnc f 1.55 0.34157   4 0.17078 0.2204 1.1, 1.9 -1.05
CC011/Unc f 2.68 0.21679   5 0.09695 0.0809 2.5, 3.0 -0.32
CC012/GeniUnc f 2.8 1.5427   5 0.68993 0.551 1.0, 4.5 -0.24
CC019/TauUnc f 4.76 4.2835   5 1.9156 0.8999 1.7, 12.0 1.02
CC024/GeniUnc f 1.5 0.42426   2   0.3 0.2828 1.2, 1.8 -1.08
CC027/GeniUnc f 2.3 0.90277   5 0.40373 0.3925 1.6, 3.7 -0.57
CC028/GeniUnc f 2.375 1.3745   4 0.68723 0.5787 1.1, 4.3 -0.52
CC030/GeniUnc f 2.34 0.80808   5 0.36139 0.3453 1.3, 3.4 -0.54
CC032/GeniUnc f 4.44 3.3568   5 1.5012 0.756 1.7, 10.1 0.81
CC035/Unc f 5.94 3.5739   5 1.5983 0.6017 2.3, 9.9 1.78
CC036/Unc f 5.38 1.9032   5 0.85112 0.3537 3.6, 8.5 1.42
CC037/TauUnc f 2.5 0.86891   5 0.38859 0.3476 1.9, 4.0 -0.44
CC040/TauUnc f 3.6 2.0559   4 1.0279 0.5711 1.9, 6.3 0.27
CC041/TauUnc f 1.38 1.064   5 0.47582 0.771 0.2, 3.1 -1.16
CC045/GeniUnc f 2.25 0.72342   4 0.36171 0.3215 1.4, 2.9 -0.6
CC059/TauUnc f 5.34 3.2974   5 1.4747 0.6175 2.1, 10.0 1.39
CC063/Unc f 6.3333 3.2716   3 1.8889 0.5166 2.6, 8.7 2.03
CC071/TauUnc f 0.96667 0.25166   3 0.1453 0.2603 0.7, 1.2 -1.43


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
CC001/Unc f 2.6 0.9053624359 4.4031855654 0.7968144346
CC002/Unc f 3.26 0.9053624359 5.0631855654 1.4568144346
CC004/TauUnc f 2.06 0.9053624359 3.8631855654 0.2568144346
CC006/TauUnc f 3.55 1.0122259755 5.5660227501 1.5339772499
CC008/GeniUnc f 1.55 1.0122259755 3.5660227501 -0.4660227501
CC011/Unc f 2.68 0.9053624359 4.4831855654 0.8768144346
CC012/GeniUnc f 2.8 0.9053624359 4.6031855654 0.9968144346
CC019/TauUnc f 4.76 0.9053624359 6.5631855654 2.9568144346
CC024/GeniUnc f 1.5 1.4315037027 4.3510867153 -1.3510867153
CC027/GeniUnc f 2.3 0.9053624359 4.1031855654 0.4968144346
CC028/GeniUnc f 2.375 1.0122259755 4.3910227501 0.3589772499
CC030/GeniUnc f 2.34 0.9053624359 4.1431855654 0.5368144346
CC032/GeniUnc f 4.44 0.9053624359 6.2431855654 2.6368144346
CC035/Unc f 5.94 0.9053624359 7.7431855654 4.1368144346
CC036/Unc f 5.38 0.9053624359 7.1831855654 3.5768144346
CC037/TauUnc f 2.5 0.9053624359 4.3031855654 0.6968144346
CC040/TauUnc f 3.6 1.0122259755 5.6160227501 1.5839772499
CC041/TauUnc f 1.38 0.9053624359 3.1831855654 -0.4231855654
CC045/GeniUnc f 2.25 1.0122259755 4.2660227501 0.2339772499
CC059/TauUnc f 5.34 0.9053624359 7.1431855654 3.5368144346
CC063/Unc f 6.3333333333 1.1688178788 8.6612358883 4.0054307784
CC071/TauUnc f 0.9666666667 1.1688178788 3.2945692216 -1.3612358883




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA