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Project measure / variable:   Auwerx2   triglyc_HFD

ID, description, units MPD:114692   triglyc_HFD   plasma triglyceride amount   [mmol/L]  HFD  
Data set, strains Auwerx2   inbred w/CC8   9 strains     sex: both     age: 21wks
Procedure lipid profile
Ontology mappings

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  STRAIN COMPARISON PLOT
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Auwerx2 - plasma triglyceride amount HFD



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested9 strains9 strains
Mean of the strain means1.2164   mmol/L 1.5146   mmol/L
Median of the strain means1.0475   mmol/L 1.45   mmol/L
SD of the strain means± 0.57537 ± 0.54683
Coefficient of variation (CV)0.473 0.361
Min–max range of strain means0.3   –   2.089   mmol/L 0.66   –   2.628   mmol/L
Mean sample size per strain4.9   mice 3.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.4801 0.4801 2.0855 0.1543
strain 7 22.1569 3.1653 13.7488 < 0.0001
sex:strain 7 2.6059 0.3723 1.617 0.1496
Residuals 56 12.8924 0.2302


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 0.906 0.24193   5 0.10819 0.267 0.52, 1.17 -0.54
129S1/SvImJ m 1.065 0.40305   2   0.285 0.3785 0.78, 1.35 -0.82
A/J f 1.0475 0.22066   4 0.11033 0.2107 0.77, 1.3 -0.29
A/J m 1.532 0.2547   5 0.1139 0.1663 1.21, 1.81 0.03
C57BL/6J f 1.0233 0.17786   3 0.10269 0.1738 0.83, 1.18 -0.34
C57BL/6J m 1.3625 0.11815   4 0.05907 0.0867 1.21, 1.47 -0.28
CAST/EiJ f 0.828 0.21288   5 0.09521 0.2571 0.53, 1.04 -0.67
CAST/EiJ m 1.45 0.43841   2   0.31 0.3023 1.14, 1.76 -0.12
DBA/2J f 1.492 0.2056   5 0.09195 0.1378 1.25, 1.72 0.48
DBA/2J m 1.842 0.24813   5 0.11097 0.1347 1.61, 2.14 0.6
NOD/ShiLtJ f 2.089 0.98816   10 0.31248 0.473 0.61, 3.74 1.52
NOD/ShiLtJ m 2.628 0.33596   5 0.15025 0.1278 2.11, 2.98 2.04
NZO/HlLtJ f 1.234 0.09864   5 0.04411 0.0799 1.14, 1.39 0.03
NZO/HlLtJ m 1.75 0.0   1   0.0 0.0 1.75, 1.75 0.43
PWK/PhJ f 2.0275 0.40566   4 0.20283 0.2001 1.62, 2.57 1.41
PWK/PhJ m 1.342 0.30817   5 0.13782 0.2296 0.96, 1.73 -0.32
WSB/EiJ f 0.3 0.23431   3 0.13528 0.781 0.03, 0.45 -1.59
WSB/EiJ m 0.66 0.49331   5 0.22061 0.7474 0.2, 1.19 -1.56


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 0.906 0.2145795862 1.3358545645 0.4761454355
129S1/SvImJ m 1.065 0.3392801159 1.7446597432 0.3853402568
A/J f 1.0475 0.2399072707 1.5280920133 0.5669079867
A/J m 1.532 0.2145795862 1.9618545645 1.1021454355
C57BL/6J f 1.0233333333 0.2770210546 1.5782731899 0.4683934768
C57BL/6J m 1.3625 0.2399072707 1.8430920133 0.8819079867
CAST/EiJ f 0.828 0.2145795862 1.2578545645 0.3981454355
CAST/EiJ m 1.45 0.3392801159 2.1296597432 0.7703402568
DBA/2J f 1.492 0.2145795862 1.9218545645 1.0621454355
DBA/2J m 1.842 0.2145795862 2.2718545645 1.4121454355
NOD/ShiLtJ f 2.089 0.1517306805 2.3929530775 1.7850469225
NOD/ShiLtJ m 2.628 0.2145795862 3.0578545645 2.1981454355
PWK/PhJ f 2.0275 0.2399072707 2.5080920133 1.5469079867
PWK/PhJ m 1.342 0.2145795862 1.7718545645 0.9121454355
WSB/EiJ f 0.3 0.2770210546 0.8549398565 -0.2549398565
WSB/EiJ m 0.66 0.2145795862 1.0898545645 0.2301454355


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 0.9855 0.2007208234 1.3875921266 0.5834078734
A/J both 1.28975 0.1609346896 1.6121409234 0.9673590766
C57BL/6J both 1.1929166667 0.1832322046 1.5599748799 0.8258584534
CAST/EiJ both 1.139 0.2007208234 1.5410921266 0.7369078734
DBA/2J both 1.667 0.1517306805 1.9709530775 1.3630469225
NOD/ShiLtJ both 2.3585 0.1314026238 2.6217310867 2.0952689133
PWK/PhJ both 1.68475 0.1609346896 2.0071409234 1.3623590766
WSB/EiJ both 0.48 0.1752034985 0.8309747822 0.1290252178




  GWAS USING LINEAR MIXED MODELS