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Project measure / variable:   Auwerx2   urea_HFD

ID, description, units MPD:114684   urea_HFD   plasma urea nitrogen amount   [mmol/L]  HFD  
Data set, strains Auwerx2   inbred w/CC8   9 strains     sex: both     age: 21wks
Procedure metabolic panel
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  STRAIN COMPARISON PLOT
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Auwerx2 - plasma urea nitrogen amount HFD



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested9 strains9 strains
Mean of the strain means7.2532   mmol/L 7.6163   mmol/L
Median of the strain means7.546   mmol/L 8.482   mmol/L
SD of the strain means± 1.6499 ± 1.9444
Coefficient of variation (CV)0.2275 0.2553
Min–max range of strain means4.9225   –   10.022   mmol/L 4.595   –   10.112   mmol/L
Mean sample size per strain4.9   mice 3.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 1.0582 1.0582 0.0803 0.778
strain 7 155.5196 22.2171 1.6853 0.1314
sex:strain 7 46.3663 6.6238 0.5025 0.8287
Residuals 56 738.2253 13.1826


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 7.884 1.4202   5 0.63513 0.1801 6.23, 9.7 0.38
129S1/SvImJ m 8.55 1.3152   2   0.93 0.1538 7.62, 9.48 0.48
A/J f 4.9225 0.45923   4 0.22961 0.0933 4.46, 5.53 -1.41
A/J m 5.804 0.21349   5 0.09548 0.0368 5.59, 6.11 -0.93
C57BL/6J f 6.0067 0.31723   3 0.18315 0.0528 5.67, 6.3 -0.76
C57BL/6J m 10.112 0.8534   4 0.4267 0.0844 8.87, 10.81 1.28
CAST/EiJ f 6.088 0.1813   5 0.08108 0.0298 5.89, 6.34 -0.71
CAST/EiJ m 4.595 0.57276   2   0.405 0.1246 4.19, 5.0 -1.55
DBA/2J f 7.546 1.734   5 0.77548 0.2298 5.24, 9.9 0.18
DBA/2J m 6.862 2.0329   5 0.90914 0.2963 5.26, 10.41 -0.39
NOD/ShiLtJ f 10.022 8.393   10 2.6541 0.8375 4.55, 33.44 1.68
NOD/ShiLtJ m 8.482 1.2802   5 0.57254 0.1509 6.58, 9.93 0.45
NZO/HlLtJ f 5.978 0.8361   5 0.37392 0.1399 4.86, 7.13 -0.77
NZO/HlLtJ m 5.63 0.0   1   0.0 0.0 5.63, 5.63 -1.02
PWK/PhJ f 7.725 0.9564   4 0.4782 0.1238 6.83, 9.08 0.29
PWK/PhJ m 9.042 1.3191   5 0.58994 0.1459 7.64, 10.64 0.73
WSB/EiJ f 9.1067 3.0743   3 1.7749 0.3376 6.13, 12.27 1.12
WSB/EiJ m 9.47 2.6011   5 1.1633 0.2747 6.23, 13.25 0.95


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 7.884 1.6237360726 11.1367342172 4.6312657828
129S1/SvImJ m 8.55 2.5673521541 13.6930243748 3.4069756252
A/J f 4.9225 1.8153921179 8.5591674112 1.2858325888
A/J m 5.804 1.6237360726 9.0567342172 2.5512657828
C57BL/6J f 6.0066666667 2.0962342559 10.2059284843 1.807404849
C57BL/6J m 10.1125 1.8153921179 13.7491674112 6.4758325888
CAST/EiJ f 6.088 1.6237360726 9.3407342172 2.8352657828
CAST/EiJ m 4.595 2.5673521541 9.7380243748 -0.5480243748
DBA/2J f 7.546 1.6237360726 10.7987342172 4.2932657828
DBA/2J m 6.862 1.6237360726 10.1147342172 3.6092657828
NOD/ShiLtJ f 10.022 1.1481547878 12.3220304224 7.7219695776
NOD/ShiLtJ m 8.482 1.6237360726 11.7347342172 5.2292657828
PWK/PhJ f 7.725 1.8153921179 11.3616674112 4.0883325888
PWK/PhJ m 9.042 1.6237360726 12.2947342172 5.7892657828
WSB/EiJ f 9.1066666667 2.0962342559 13.3059284843 4.907404849
WSB/EiJ m 9.47 1.6237360726 12.7227342172 6.2172657828


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 8.217 1.5188660175 11.2596542528 5.1743457472
A/J both 5.36325 1.2178020544 7.8028006629 2.9236993371
C57BL/6J both 8.0595833333 1.3865286327 10.8371339482 5.2820327185
CAST/EiJ both 5.3415 1.5188660175 8.3841542528 2.2988457472
DBA/2J both 7.204 1.1481547878 9.5040304224 4.9039695776
NOD/ShiLtJ both 9.252 0.9943312137 11.2438847753 7.2601152247
PWK/PhJ both 8.3835 1.2178020544 10.8230506629 5.9439493371
WSB/EiJ both 9.2883333333 1.3257749516 11.9441797004 6.6324869663




  GWAS USING LINEAR MIXED MODELS