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Project measure / variable:   Auwerx2   iron_CD

ID, description, units MPD:114677   iron_CD   plasma iron amount   [mmol/L]  CD  
Data set, strains Auwerx2   inbred w/CC8   9 strains     sex: both     age: 21wks
Procedure metabolic panel
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  STRAIN COMPARISON PLOT
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Auwerx2 - plasma iron amount CD



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested9 strains9 strains
Mean of the strain means16.025   mmol/L 15.603   mmol/L
Median of the strain means15.8   mmol/L 13.1   mmol/L
SD of the strain means± 6.0705 ± 6.2595
Coefficient of variation (CV)0.3788 0.4012
Min–max range of strain means6.34   –   26.033   mmol/L 8.2   –   26.14   mmol/L
Mean sample size per strain4.4   mice 4.7   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.2371 0.2371 0.0073 0.9322
strain 7 2302.1278 328.8754 10.1348 < 0.0001
sex:strain 7 349.9369 49.991 1.5406 0.1705
Residuals 62 2011.9005 32.45


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 15.78 7.8088   5 3.4922 0.4949 4.9, 23.7 -0.04
129S1/SvImJ m 8.2 3.1718   5 1.4184 0.3868 2.9, 11.2 -1.18
A/J f 19.24 3.4725   5 1.5529 0.1805 14.9, 24.5 0.53
A/J m 12.575 1.524   4 0.76199 0.1212 11.0, 14.4 -0.48
C57BL/6J f 6.34 2.1606   5 0.96623 0.3408 2.9, 8.5 -1.6
C57BL/6J m 9.12 2.4479   5 1.0947 0.2684 6.2, 11.8 -1.04
CAST/EiJ f 12.3 0.0   1   0.0 0.0 12.3, 12.3 -0.61
CAST/EiJ m 10.633 9.25   3 5.3405 0.8699 0.7, 19.0 -0.79
DBA/2J f 19.44 11.67   5 5.2189 0.6003 2.2, 35.1 0.56
DBA/2J m 21.14 5.7426   5 2.5682 0.2716 13.0, 28.6 0.88
NOD/ShiLtJ f 20.171 3.8003   7 1.4364 0.1884 14.3, 24.7 0.68
NOD/ShiLtJ m 19.42 6.4998   5 2.9068 0.3347 10.7, 28.4 0.61
NZO/HlLtJ f 15.8 2.3735   4 1.1867 0.1502 12.4, 17.7 -0.04
NZO/HlLtJ m 20.1 7.3644   5 3.2935 0.3664 10.9, 29.0 0.72
PWK/PhJ f 9.12 3.6176   5 1.6178 0.3967 3.1, 11.9 -1.14
PWK/PhJ m 13.1 8.2009   5 3.6676 0.626 5.2, 22.1 -0.4
WSB/EiJ f 26.033 4.8645   3 2.8085 0.1869 22.6, 31.6 1.65
WSB/EiJ m 26.14 4.8758   5 2.1805 0.1865 22.3, 34.2 1.68


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 15.78 2.547548127 20.8724761441 10.6875238559
129S1/SvImJ m 8.2 2.547548127 13.2924761441 3.1075238559
A/J f 19.24 2.547548127 24.3324761441 14.1475238559
A/J m 12.575 2.8482453939 18.268561416 6.881438584
C57BL/6J f 6.34 2.547548127 11.4324761441 1.2475238559
C57BL/6J m 9.12 2.547548127 14.2124761441 4.0275238559
DBA/2J f 19.44 2.547548127 24.5324761441 14.3475238559
DBA/2J m 21.14 2.547548127 26.2324761441 16.0475238559
NOD/ShiLtJ f 20.1714285714 2.1530711386 24.4753564517 15.8675006911
NOD/ShiLtJ m 19.42 2.547548127 24.5124761441 14.3275238559
NZO/HlLtJ f 15.8 2.8482453939 21.493561416 10.106438584
NZO/HlLtJ m 20.1 2.547548127 25.1924761441 15.0075238559
PWK/PhJ f 9.12 2.547548127 14.2124761441 4.0275238559
PWK/PhJ m 13.1 2.547548127 18.1924761441 8.0075238559
WSB/EiJ f 26.0333333333 3.2888704898 32.6076917657 19.458974901
WSB/EiJ m 26.14 2.547548127 31.2324761441 21.0475238559


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 11.99 1.801388556 15.5909244145 8.3890755855
A/J both 15.9075 1.9106610952 19.7268571081 12.0881428919
C57BL/6J both 7.73 1.801388556 11.3309244145 4.1290755855
DBA/2J both 20.29 1.801388556 23.8909244145 16.6890755855
NOD/ShiLtJ both 19.7957142857 1.6677617326 23.1295224864 16.461906085
NZO/HlLtJ both 17.95 1.9106610952 21.7693571081 14.1306428919
PWK/PhJ both 11.11 1.801388556 14.7109244145 7.5090755855
WSB/EiJ both 26.0866666667 2.0800643354 30.2446560268 21.9286773065




  GWAS USING LINEAR MIXED MODELS