Project measure / variable:   Auwerx2   gastroc_wt_HFD

ID, description, units MPD:114654   gastroc_wt_HFD   gastrocnemius muscle weight   [g]  HFD  
Data set, strains Auwerx2   inbred w/CC8   9 strains     sex: both     age: 21wks
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  STRAIN COMPARISON PLOT
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Auwerx2 - gastrocnemius muscle weight HFD



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested9 strains9 strains
Mean of the strain means0.21651   g 0.24602   g
Median of the strain means0.22077   g 0.25024   g
SD of the strain means± 0.03573 ± 0.05163
Coefficient of variation (CV)0.165 0.2099
Min–max range of strain means0.17008   –   0.26508   g 0.15396   –   0.31142   g
Mean sample size per strain4.4   mice 3.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.0182 0.0182 46.9536 < 0.0001
strain 7 0.1245 0.0178 45.96 < 0.0001
sex:strain 7 0.0123 0.0018 4.5348 0.0005
Residuals 52 0.0201 0.0004


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 0.2086 0.01508   5 0.00674559 0.0723 0.1907, 0.232 -0.22
129S1/SvImJ m 0.2114 0.02291   2   0.0162 0.1084 0.1952, 0.2276 -0.67
A/J f 0.22077 0.02309   4 0.01155 0.1046 0.202, 0.2493 0.12
A/J m 0.25024 0.02182   5 0.00975903 0.0872 0.2234, 0.277 0.08
C57BL/6J f 0.23477 0.00627482   3 0.00362277 0.0267 0.2301, 0.2419 0.51
C57BL/6J m 0.31142 0.01573   4 0.00786674 0.0505 0.2941, 0.3323 1.27
CAST/EiJ f 0.17008 0.01004   5 0.00449148 0.0591 0.1631, 0.1874 -1.3
CAST/EiJ m 0.2151 0.00212132   2   0.0015 0.0099 0.2136, 0.2166 -0.6
DBA/2J f 0.24472 0.03351   5 0.01499 0.137 0.2114, 0.2928 0.79
DBA/2J m 0.30478 0.02448   5 0.01095 0.0803 0.272, 0.3339 1.14
NOD/ShiLtJ f 0.26508 0.01395   6 0.00569423 0.0526 0.2466, 0.2897 1.36
NOD/ShiLtJ m 0.28924 0.02731   5 0.01221 0.0944 0.2722, 0.3375 0.84
NZO/HlLtJ f 0.25146 0.03266   5 0.0146 0.1299 0.2014, 0.2825 0.98
NZO/HlLtJ m 0.2612 0.0   1   0.0 0.0 0.2612, 0.2612 0.29
PWK/PhJ f 0.17055 0.0064959   4 0.00324795 0.0381 0.1623, 0.1781 -1.29
PWK/PhJ m 0.15396 0.01897   5 0.00848343 0.1232 0.1271, 0.1794 -1.78
WSB/EiJ f 0.18257 0.0124   3 0.00715782 0.0679 0.1731, 0.1966 -0.95
WSB/EiJ m 0.21686 0.01756   5 0.00785115 0.081 0.1978, 0.2349 -0.56


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 0.2086 0.0087971234 0.2262527195 0.1909472805
129S1/SvImJ m 0.2114 0.0139094733 0.2393114002 0.1834885998
A/J f 0.220775 0.0098354829 0.2405113404 0.2010386596
A/J m 0.25024 0.0087971234 0.2678927195 0.2325872805
C57BL/6J f 0.2347666667 0.0113570374 0.2575562295 0.2119771038
C57BL/6J m 0.311425 0.0098354829 0.3311613404 0.2916886596
CAST/EiJ f 0.17008 0.0087971234 0.1877327195 0.1524272805
CAST/EiJ m 0.2151 0.0139094733 0.2430114002 0.1871885998
DBA/2J f 0.24472 0.0087971234 0.2623727195 0.2270672805
DBA/2J m 0.30478 0.0087971234 0.3224327195 0.2871272805
NOD/ShiLtJ f 0.2650833333 0.0080306382 0.2811979878 0.2489686789
NOD/ShiLtJ m 0.28924 0.0087971234 0.3068927195 0.2715872805
PWK/PhJ f 0.17055 0.0098354829 0.1902863404 0.1508136596
PWK/PhJ m 0.15396 0.0087971234 0.1716127195 0.1363072805
WSB/EiJ f 0.1825666667 0.0113570374 0.2053562295 0.1597771038
WSB/EiJ m 0.21686 0.0087971234 0.2345127195 0.1992072805


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 0.21 0.0082289554 0.2265126071 0.1934873929
A/J both 0.2355075 0.0065978425 0.2487470396 0.2222679604
C57BL/6J both 0.2730958333 0.0075119742 0.2881697123 0.2580219544
CAST/EiJ both 0.19259 0.0082289554 0.2091026071 0.1760773929
DBA/2J both 0.27475 0.0062205056 0.2872323577 0.2622676423
NOD/ShiLtJ both 0.2771616667 0.0059556807 0.2891126143 0.2652107191
PWK/PhJ both 0.162255 0.0065978425 0.1754945396 0.1490154604
WSB/EiJ both 0.1997133333 0.0071828211 0.2141267184 0.1852999482




  GWAS USING LINEAR MIXED MODELS