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Project measure / variable:   Auwerx2   bw_21wks_sac_HFD

ID, description, units MPD:114650   bw_21wks_sac_HFD   body weight at sacrifice   [g]  HFD  
Data set, strains Auwerx2   inbred w/CC8   9 strains     sex: both     age: 21wks
Procedure body weight
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  STRAIN COMPARISON PLOT
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Auwerx2 - body weight at sacrifice HFD



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested9 strains9 strains
Mean of the strain means30.643   g 34.698   g
Median of the strain means24.797   g 32.73   g
SD of the strain means± 20.584 ± 17.414
Coefficient of variation (CV)0.6717 0.5019
Min–max range of strain means12.42   –   80.95   g 15.638   –   72.95   g
Mean sample size per strain4.4   mice 3.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 490.6755 490.6755 61.39 < 0.0001
strain 7 5200.0579 742.8654 92.9423 < 0.0001
sex:strain 7 355.8786 50.8398 6.3607 < 0.0001
Residuals 52 415.6235 7.9928


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 23.122 0.86053   5 0.38484 0.0372 22.36, 24.52 -0.37
129S1/SvImJ m 32.73 1.1172   2   0.79 0.0341 31.94, 33.52 -0.11
A/J f 23.043 2.2855   4 1.1428 0.0992 21.06, 26.34 -0.37
A/J m 28.018 2.3117   5 1.0338 0.0825 25.68, 30.83 -0.38
C57BL/6J f 29.56 5.7552   3 3.3228 0.1947 24.81, 35.96 -0.05
C57BL/6J m 46.332 3.0513   4 1.5257 0.0659 41.97, 49.03 0.67
CAST/EiJ f 12.42 0.63332   5 0.28323 0.051 11.59, 13.17 -0.89
CAST/EiJ m 17.48 1.9799   2   1.4 0.1133 16.08, 18.88 -0.99
DBA/2J f 38.404 3.8   5 1.6994 0.0989 33.55, 42.6 0.38
DBA/2J m 40.48 3.5819   5 1.6019 0.0885 36.5, 45.97 0.33
NOD/ShiLtJ f 30.642 3.718   6 1.5179 0.1213 28.07, 37.91 0.0
NOD/ShiLtJ m 33.064 1.8502   5 0.82743 0.056 31.3, 36.08 -0.09
NZO/HlLtJ f 80.95 1.9284   5 0.86239 0.0238 78.85, 83.37 2.44
NZO/HlLtJ m 72.95 0.0   1   0.0 0.0 72.95, 72.95 2.2
PWK/PhJ f 24.797 1.871   4 0.93548 0.0754 22.71, 27.1 -0.28
PWK/PhJ m 25.588 4.1283   5 1.8462 0.1613 20.45, 30.61 -0.52
WSB/EiJ f 12.847 0.50649   3 0.29242 0.0394 12.46, 13.42 -0.86
WSB/EiJ m 15.638 0.94695   5 0.42349 0.0606 14.84, 17.24 -1.09


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 23.122 1.2643385851 25.6590809822 20.5849190178
129S1/SvImJ m 32.73 1.9990948312 36.7414772561 28.7185227439
A/J f 23.0425 1.4135735114 25.8790427704 20.2059572296
A/J m 28.018 1.2643385851 30.5550809822 25.4809190178
C57BL/6J f 29.56 1.6322540946 32.8353574641 26.2846425359
C57BL/6J m 46.3325 1.4135735114 49.1690427704 43.4959572296
CAST/EiJ f 12.42 1.2643385851 14.9570809822 9.8829190178
CAST/EiJ m 17.48 1.9990948312 21.4914772561 13.4685227439
DBA/2J f 38.404 1.2643385851 40.9410809822 35.8669190178
DBA/2J m 40.48 1.2643385851 43.0170809822 37.9429190178
NOD/ShiLtJ f 30.6416666667 1.1541779389 32.9576941403 28.325639193
NOD/ShiLtJ m 33.064 1.2643385851 35.6010809822 30.5269190178
PWK/PhJ f 24.7975 1.4135735114 27.6340427704 21.9609572296
PWK/PhJ m 25.588 1.2643385851 28.1250809822 23.0509190178
WSB/EiJ f 12.8466666667 1.6322540946 16.1220241307 9.5713092026
WSB/EiJ m 15.638 1.2643385851 18.1750809822 13.1009190178


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 27.926 1.1826804516 30.2992219495 25.5527780505
A/J both 25.53025 0.9482539388 27.4330607367 23.6274392633
C57BL/6J both 37.94625 1.0796346027 40.1126953262 35.7798046738
CAST/EiJ both 14.95 1.1826804516 17.3232219495 12.5767780505
DBA/2J both 39.442 0.8940223872 41.235987167 37.648012833
NOD/ShiLtJ both 31.8528333333 0.8559612685 33.570445278 30.1352213887
PWK/PhJ both 25.19275 0.9482539388 27.0955607367 23.2899392633
WSB/EiJ both 14.2423333333 1.0323281318 16.3138512809 12.1708153858




  GWAS USING LINEAR MIXED MODELS