Project measure / variable:   Auwerx2   vert_act_day_HFD

ID, description, units MPD:114626   vert_act_day_HFD   vertical activity (beam breaks) during day, basal activity test, for 48h   [n/h]  HFD  
Data set, strains Auwerx2   inbred w/CC8   9 strains     sex: both     age: 19wks
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  STRAIN COMPARISON PLOT
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Auwerx2 - vertical activity (beam breaks) during day, basal activity test, for 48h HFD



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested9 strains8 strains
Mean of the strain means4996.0   n/h 1934.0   n/h
Median of the strain means2479.0   n/h 1303.0   n/h
SD of the strain means± 4882.0 ± 2679.0
Coefficient of variation (CV)0.9772 1.3858
Min–max range of strain means284.2   –   11594.0   n/h 217.4   –   8396.0   n/h
Mean sample size per strain3.8   mice 4.1   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 148144873.0179 148144873.0179 3.9911 0.0522
strain 6 572386300.3242 95397716.7207 2.5701 0.0327
sex:strain 6 241659483.0972 40276580.5162 1.0851 0.3869
Residuals 42 1558981158.4 37118599.0095


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 552.2 411.5   5 184.0 0.7452 170.0, 1139.0 -0.91
129S1/SvImJ m 250.5 70.0   2   49.5 0.2795 201.0, 300.0 -0.63
A/J f 284.2 67.64   4 33.822 0.238 185.0, 337.0 -0.97
A/J m 217.4 125.7   5 56.21 0.5781 80.0, 351.0 -0.64
C57BL/6J f 11594.0 4451.0   3 2570.0 0.3839 8726.0, 16722.0 1.35
C57BL/6J m 1299.0 801.2   4 400.6 0.6166 576.0, 2293.0 -0.24
CAST/EiJ f 9793.0 7301.0   5 3265.0 0.7455 3398.0, 21376.0 0.98
CAST/EiJ m 1307.0 188.1   2   133.0 0.1439 1174.0, 1440.0 -0.23
DBA/2J f 2479.0 3140.0   5 1404.0 1.2666 126.0, 6782.0 -0.52
DBA/2J m 694.8 556.6   5 248.9 0.8011 267.0, 1388.0 -0.46
NOD/ShiLtJ f 885.0 0.0   1   0.0 0.0 885.0, 885.0 -0.84
NOD/ShiLtJ m 1314.0 780.6   5 349.1 0.5939 710.0, 2619.0 -0.23
NZO/HlLtJ f 760.8 466.3   5 208.5 0.6129 339.0, 1380.0 -0.87
PWK/PhJ f 7920.0 2075.0   3 1198.0 0.262 6576.0, 10309.0 0.6
PWK/PhJ m 8396.0 14967.0   5 6693.0 1.7826 509.0, 35013.0 2.41
WSB/EiJ f 10694.0 13031.0   3 7524.0 1.2185 2564.0, 25725.0 1.17
WSB/EiJ m 1990.0 2152.0   5 962.4 1.0815 641.0, 5806.0 0.02


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 552.2 2724.6503999421 6050.7671187001 -4946.3671187002
129S1/SvImJ m 250.5 4308.0505457529 8944.4979812009 -8443.497981201
A/J f 284.25 3046.2517545963 6431.8349281293 -5863.3349281293
A/J m 217.4 2724.6503999421 5715.9671187002 -5281.1671187001
C57BL/6J f 11594.3333333333 3517.5085410711 18692.9529595765 4495.7137070902
C57BL/6J m 1299.25 3046.2517545963 7446.8349281293 -4848.3349281293
CAST/EiJ f 9793.4 2724.6503999421 15291.9671187002 4294.8328812998
CAST/EiJ m 1307.0 4308.0505457529 10000.997981201 -7386.9979812009
DBA/2J f 2478.8 2724.6503999421 7977.3671187002 -3019.7671187002
DBA/2J m 694.8 2724.6503999421 6193.3671187001 -4803.7671187001
PWK/PhJ f 7919.6666666667 3517.5085410711 15018.2862929098 821.0470404235
PWK/PhJ m 8395.8 2724.6503999421 13894.3671187002 2897.2328812999
WSB/EiJ f 10694.3333333333 3517.5085410711 17792.9529595765 3595.7137070902
WSB/EiJ m 1989.8 2724.6503999421 7488.3671187001 -3508.7671187002


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 401.35 2548.67707383 5544.7885690892 -4742.0885690892
A/J both 250.825 2043.4877999566 4374.7503390251 -3873.1003390251
C57BL/6J both 6446.7916666667 2326.6132085549 11142.0872123871 1751.4961209463
CAST/EiJ both 5550.2 2548.67707383 10693.6385690892 406.7614309108
DBA/2J both 1586.8 1926.6187741617 5474.8740964423 -2301.2740964423
PWK/PhJ both 8157.7333333333 2224.6677357761 12647.2945857536 3668.172080913
WSB/EiJ both 6342.0666666667 2224.6677357761 10831.627919087 1852.5054142464




  GWAS USING LINEAR MIXED MODELS