Project measure / variable:   Auwerx2   vert_act_day_CD

ID, description, units MPD:114625   vert_act_day_CD   vertical activity (beam breaks) during day, basal activity test, for 48h   [n/h]  CD  
Data set, strains Auwerx2   inbred w/CC8   9 strains     sex: both     age: 19wks
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  STRAIN COMPARISON PLOT
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Auwerx2 - vertical activity (beam breaks) during day, basal activity test, for 48h CD



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested9 strains9 strains
Mean of the strain means4247.0   n/h 2818.0   n/h
Median of the strain means1950.0   n/h 2846.0   n/h
SD of the strain means± 6535.0 ± 2247.0
Coefficient of variation (CV)1.5386 0.7975
Min–max range of strain means354.6   –   21343.0   n/h 203.8   –   6978.0   n/h
Mean sample size per strain4.3   mice 4.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 4643608.2333 4643608.2333 0.9861 0.3246
strain 7 189478241.386 27068320.198 5.7478 < 0.0001
sex:strain 7 65695868.414 9385124.0591 1.9929 0.0703
Residuals 62 291976631.3 4709300.5048


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 1484.0 488.0   5 218.2 0.3287 942.0, 2208.0 -0.42
129S1/SvImJ m 787.2 349.2   5 156.1 0.4435 399.0, 1298.0 -0.9
A/J f 354.6 439.4   5 196.5 1.2392 52.0, 1129.0 -0.6
A/J m 203.8 184.3   5 82.44 0.9045 31.0, 464.0 -1.16
C57BL/6J f 2927.0 1231.0   5 550.5 0.4206 2096.0, 5107.0 -0.2
C57BL/6J m 6978.0 1366.0   5 611.1 0.1958 4772.0, 8434.0 1.85
CAST/EiJ f 21343.0 0.0   1   0.0 0.0 21343.0, 21343.0 2.62
CAST/EiJ m 4006.0 1954.0   3 1128.0 0.4878 1892.0, 5746.0 0.53
DBA/2J f 3934.0 6130.0   5 2741.0 1.5581 742.0, 14878.0 -0.05
DBA/2J m 2846.0 2441.0   5 1092.0 0.8579 664.0, 7016.0 0.01
NOD/ShiLtJ f 1950.0 1505.0   6 614.3 0.7719 528.0, 3849.0 -0.35
NOD/ShiLtJ m 4907.0 3129.0   5 1399.0 0.6376 2063.0, 9206.0 0.93
NZO/HlLtJ f 1074.0 520.8   4 260.4 0.4851 354.0, 1515.0 -0.49
NZO/HlLtJ m 1947.0 513.0   5 229.4 0.2635 1259.0, 2443.0 -0.39
PWK/PhJ f 3956.0 2479.0   5 1109.0 0.6267 2100.0, 8320.0 -0.04
PWK/PhJ m 3201.0 2471.0   5 1105.0 0.7719 1143.0, 7394.0 0.17
WSB/EiJ f 1202.0 438.3   3 253.1 0.3646 940.0, 1708.0 -0.47
WSB/EiJ m 482.8 227.2   5 101.6 0.4707 193.0, 770.0 -1.04


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 1484.4 970.4947712212 3424.3914051011 -455.5914051011
129S1/SvImJ m 787.2 970.4947712212 2727.1914051011 -1152.7914051011
A/J f 354.6 970.4947712212 2294.5914051011 -1585.3914051011
A/J m 203.8 970.4947712212 2143.7914051011 -1736.1914051011
C57BL/6J f 2926.6 970.4947712212 4866.5914051011 986.6085948989
C57BL/6J m 6978.0 970.4947712212 8917.9914051011 5038.0085948989
DBA/2J f 3934.4 970.4947712212 5874.3914051011 1994.4085948989
DBA/2J m 2845.8 970.4947712212 4785.7914051011 905.8085948989
NOD/ShiLtJ f 1949.5 885.9364635645 3720.4617565667 178.5382434333
NOD/ShiLtJ m 4907.4 970.4947712212 6847.3914051011 2967.4085948989
NZO/HlLtJ f 1073.5 1085.0461401294 3242.4763287856 -1095.4763287857
NZO/HlLtJ m 1947.0 970.4947712212 3886.9914051011 7.0085948989
PWK/PhJ f 3956.2 970.4947712212 5896.1914051011 2016.2085948989
PWK/PhJ m 3201.2 970.4947712212 5141.1914051011 1261.2085948989
WSB/EiJ f 1202.0 1252.9033621737 3706.5181345806 -1302.5181345806
WSB/EiJ m 482.8 970.4947712212 2422.7914051011 -1457.1914051011


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 1135.8 686.2434338366 2507.5810779906 -235.9810779906
A/J both 279.2 686.2434338366 1650.9810779906 -1092.5810779906
C57BL/6J both 4952.3 686.2434338366 6324.0810779906 3580.5189220094
DBA/2J both 3390.1 686.2434338366 4761.8810779906 2018.3189220094
NOD/ShiLtJ both 3428.45 657.028066075 4741.8303899754 2115.0696100246
NZO/HlLtJ both 1510.25 727.8710784159 2965.2435538258 55.2564461742
PWK/PhJ both 3578.7 686.2434338366 4950.4810779906 2206.9189220094
WSB/EiJ both 842.4 792.4056625104 2426.3963492942 -741.5963492942




  GWAS USING LINEAR MIXED MODELS