Project measure / variable:   Auwerx2   temp_t6_HFD

ID, description, units MPD:114620   temp_t6_HFD   body temperature (rectal) in cold (4°C) room, 6h exposed to cold   [°C]  HFD  
Data set, strains Auwerx2   inbred w/CC8   9 strains     sex: both     age: 18wks
Procedure body temperature
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  STRAIN COMPARISON PLOT
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Auwerx2 - body temperature (rectal) in cold (4°C) room, 6h exposed to cold HFD



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested9 strains9 strains
Mean of the strain means34.525   °C 34.264   °C
Median of the strain means34.6   °C 34.7   °C
SD of the strain means± 1.3381 ± 1.7835
Coefficient of variation (CV)0.0388 0.0521
Min–max range of strain means31.967   –   36.633   °C 31.6   –   37.06   °C
Mean sample size per strain4.2   mice 3.7   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 0.369 0.369 0.5409 0.4654
strain 7 64.3421 9.1917 13.4733 < 0.0001
sex:strain 7 35.7522 5.1075 7.4865 < 0.0001
Residuals 51 34.7932 0.6822


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 34.52 1.3882   5 0.62081 0.0402 33.0, 36.5 0.0
129S1/SvImJ m 35.0 0.0   2   0.0 0.0 35.0, 35.0 0.41
A/J f 34.1 1.0198   4 0.5099 0.0299 32.7, 35.1 -0.32
A/J m 34.98 0.43243   5 0.19339 0.0124 34.5, 35.6 0.4
C57BL/6J f 34.6 0.6245   3 0.36056 0.018 34.1, 35.3 0.06
C57BL/6J m 33.1 0.40825   4 0.20412 0.0123 32.5, 33.4 -0.65
CAST/EiJ f 33.44 1.9087   5 0.85358 0.0571 30.6, 35.4 -0.81
CAST/EiJ m 35.6 0.70711   2   0.5 0.0199 35.1, 36.1 0.75
DBA/2J f 34.74 0.43359   5 0.19391 0.0125 34.2, 35.4 0.16
DBA/2J m 34.54 0.41593   5 0.18601 0.012 34.1, 35.2 0.15
NOD/ShiLtJ f 34.85 0.50892   6 0.20777 0.0146 34.2, 35.5 0.24
NOD/ShiLtJ m 31.8 0.63246   4 0.31623 0.0199 31.2, 32.6 -1.38
NZO/HlLtJ f 31.967 0.30551   3 0.17638 0.0096 31.7, 32.3 -1.91
NZO/HlLtJ m 31.6 0.0   1   0.0 0.0 31.6, 31.6 -1.49
PWK/PhJ f 35.875 0.38622   4 0.19311 0.0108 35.3, 36.1 1.01
PWK/PhJ m 34.7 0.25495   5 0.11402 0.0073 34.3, 34.9 0.24
WSB/EiJ f 36.633 1.0116   3 0.58405 0.0276 36.0, 37.8 1.58
WSB/EiJ m 37.06 0.20736   5 0.09274 0.0056 36.7, 37.2 1.57


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 34.52 0.3693829867 35.2615672891 33.7784327109
129S1/SvImJ m 35.0 0.5840457834 36.1725208359 33.8274791641
A/J f 34.1 0.412982734 34.9290974342 33.2709025658
A/J m 34.98 0.3693829867 35.7215672891 34.2384327109
C57BL/6J f 34.6 0.4768713853 35.5573592536 33.6426407464
C57BL/6J m 33.1 0.412982734 33.9290974342 32.2709025658
CAST/EiJ f 33.44 0.3693829867 34.1815672891 32.6984327109
CAST/EiJ m 35.6 0.5840457834 36.7725208359 34.4274791641
DBA/2J f 34.74 0.3693829867 35.4815672891 33.9984327109
DBA/2J m 34.54 0.3693829867 35.2815672891 33.7984327109
NOD/ShiLtJ f 34.85 0.3371989903 35.5269552202 34.1730447798
NOD/ShiLtJ m 31.8 0.412982734 32.6290974342 30.9709025658
PWK/PhJ f 35.875 0.412982734 36.7040974342 35.0459025658
PWK/PhJ m 34.7 0.3693829867 35.4415672891 33.9584327109
WSB/EiJ f 36.6333333333 0.4768713853 37.5906925869 35.6759740798
WSB/EiJ m 37.06 0.3693829867 37.8015672891 36.3184327109


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 34.76 0.3455261452 35.4536726813 34.0663273187
A/J both 34.54 0.27703724 35.0961754668 33.9838245332
C57BL/6J both 33.85 0.3154207732 34.4832336251 33.2167663749
CAST/EiJ both 34.52 0.3455261452 35.2136726813 33.8263273187
DBA/2J both 34.64 0.2611932147 35.1643672588 34.1156327412
NOD/ShiLtJ both 33.325 0.2665792085 33.8601800925 32.7898199075
PWK/PhJ both 35.2875 0.27703724 35.8436754668 34.7313245332
WSB/EiJ both 36.8466666667 0.3015999457 37.4521538227 36.2411795106




  GWAS USING LINEAR MIXED MODELS