Project measure / variable:   Auwerx2   temp_t4_HFD

ID, description, units MPD:114616   temp_t4_HFD   body temperature (rectal) in cold (4°C) room, 4h exposed to cold   [°C]  HFD  
Data set, strains Auwerx2   inbred w/CC8   9 strains     sex: both     age: 18wks
Procedure body temperature
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  STRAIN COMPARISON PLOT
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Auwerx2 - body temperature (rectal) in cold (4°C) room, 4h exposed to cold HFD



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested9 strains9 strains
Mean of the strain means34.707   °C 34.491   °C
Median of the strain means34.967   °C 34.96   °C
SD of the strain means± 1.3082 ± 1.3595
Coefficient of variation (CV)0.0377 0.0394
Min–max range of strain means31.625   –   36.1   °C 32.8   –   36.74   °C
Mean sample size per strain4.3   mice 3.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 2.1403 2.1403 5.7416 0.0202
strain 7 40.9341 5.8477 15.6871 < 0.0001
sex:strain 7 23.9426 3.4204 9.1755 < 0.0001
Residuals 52 19.3842 0.3728


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 34.8 0.84261   5 0.37683 0.0242 33.5, 35.7 0.07
129S1/SvImJ m 34.7 0.42426   2   0.3 0.0122 34.4, 35.0 0.15
A/J f 34.325 1.3598   4 0.67992 0.0396 32.3, 35.2 -0.29
A/J m 34.98 0.31937   5 0.14283 0.0091 34.6, 35.4 0.36
C57BL/6J f 34.967 0.11547   3 0.06667 0.0033 34.9, 35.1 0.2
C57BL/6J m 32.95 0.56862   4 0.28431 0.0173 32.6, 33.8 -1.13
CAST/EiJ f 34.36 0.63482   5 0.2839 0.0185 33.4, 35.1 -0.27
CAST/EiJ m 35.45 0.35355   2   0.25 0.01 35.2, 35.7 0.71
DBA/2J f 35.1 0.43012   5 0.19235 0.0123 34.7, 35.8 0.3
DBA/2J m 35.02 0.63008   5 0.28178 0.018 34.2, 35.6 0.39
NOD/ShiLtJ f 35.117 0.57764   6 0.23582 0.0164 34.0, 35.5 0.31
NOD/ShiLtJ m 32.82 0.38987   5 0.17436 0.0119 32.4, 33.2 -1.23
NZO/HlLtJ f 31.625 1.3475   4 0.67376 0.0426 29.8, 33.0 -2.36
NZO/HlLtJ m 32.8 0.0   1   0.0 0.0 32.8, 32.8 -1.24
PWK/PhJ f 36.1 0.37417   4 0.18708 0.0104 35.6, 36.5 1.06
PWK/PhJ m 34.96 0.21909   5 0.09798 0.0063 34.7, 35.3 0.34
WSB/EiJ f 35.967 0.05774   3 0.03333 0.0016 35.9, 36.0 0.96
WSB/EiJ m 36.74 0.78294   5 0.35014 0.0213 35.9, 37.8 1.65


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 34.8 0.2730466758 35.3479082397 34.2520917603
129S1/SvImJ m 34.7 0.4317247016 35.5663189931 33.8336810069
A/J f 34.325 0.3052754641 34.9375800347 33.7124199653
A/J m 34.98 0.2730466758 35.5279082397 34.4320917603
C57BL/6J f 34.9666666667 0.3525017427 35.6740131625 34.2593201708
C57BL/6J m 32.95 0.3052754641 33.5625800347 32.3374199653
CAST/EiJ f 34.36 0.2730466758 34.9079082397 33.8120917603
CAST/EiJ m 35.45 0.4317247016 36.3163189931 34.5836810069
DBA/2J f 35.1 0.2730466758 35.6479082397 34.5520917603
DBA/2J m 35.02 0.2730466758 35.5679082397 34.4720917603
NOD/ShiLtJ f 35.1166666667 0.2492563727 35.6168361705 34.6164971628
NOD/ShiLtJ m 32.82 0.2730466758 33.3679082397 32.2720917603
PWK/PhJ f 36.1 0.3052754641 36.7125800347 35.4874199653
PWK/PhJ m 34.96 0.2730466758 35.5079082397 34.4120917603
WSB/EiJ f 35.9666666667 0.3525017427 36.6740131625 35.2593201708
WSB/EiJ m 36.74 0.2730466758 37.2879082397 36.1920917603


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 34.75 0.2554117779 35.2625212281 34.2374787719
A/J both 34.6525 0.2047850069 35.0634311798 34.2415688202
C57BL/6J both 33.9583333333 0.233157987 34.426199063 33.4904676036
CAST/EiJ both 34.905 0.2554117779 35.4175212281 34.3924787719
DBA/2J both 35.06 0.1930731561 35.4474296317 34.6725703683
NOD/ShiLtJ both 33.9683333333 0.1848534734 34.3392689651 33.5973977016
PWK/PhJ both 35.53 0.2047850069 35.9409311798 35.1190688202
WSB/EiJ both 36.3533333333 0.2229416772 36.8006985377 35.905968129




  GWAS USING LINEAR MIXED MODELS