Project measure / variable:   Auwerx2   temp_t1_HFD

ID, description, units MPD:114610   temp_t1_HFD   body temperature (rectal) in cold (4°C) room, 1h exposed to cold   [°C]  HFD  
Data set, strains Auwerx2   inbred w/CC8   9 strains     sex: both     age: 18wks
Procedure body temperature
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  STRAIN COMPARISON PLOT
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Auwerx2 - body temperature (rectal) in cold (4°C) room, 1h exposed to cold HFD



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested9 strains9 strains
Mean of the strain means35.628   °C 35.347   °C
Median of the strain means35.625   °C 35.5   °C
SD of the strain means± 0.79255 ± 0.8471
Coefficient of variation (CV)0.0222 0.024
Min–max range of strain means34.02   –   37.067   °C 34.2   –   36.24   °C
Mean sample size per strain4.4   mice 3.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 2.3117 2.3117 9.2982 0.0036
strain 7 20.106 2.8723 11.553 < 0.0001
sex:strain 7 5.0863 0.7266 2.9226 0.0118
Residuals 52 12.9282 0.2486


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 35.56 0.4219   5 0.18868 0.0119 35.1, 35.9 -0.09
129S1/SvImJ m 36.15 0.07071   2   0.05 0.002 36.1, 36.2 0.95
A/J f 35.625 0.27538   4 0.13769 0.0077 35.3, 35.9 0.0
A/J m 35.38 0.29496   5 0.13191 0.0083 35.0, 35.8 0.04
C57BL/6J f 35.467 0.85049   3 0.49103 0.024 34.6, 36.3 -0.2
C57BL/6J m 34.2 0.4761   4 0.23805 0.0139 33.7, 34.7 -1.35
CAST/EiJ f 35.7 0.33912   5 0.15166 0.0095 35.3, 36.2 0.09
CAST/EiJ m 36.15 0.07071   2   0.05 0.002 36.1, 36.2 0.95
DBA/2J f 35.78 0.46583   5 0.20833 0.013 35.2, 36.3 0.19
DBA/2J m 35.5 0.73485   5 0.32863 0.0207 34.9, 36.7 0.18
NOD/ShiLtJ f 35.333 0.66533   6 0.27162 0.0188 34.1, 36.0 -0.37
NOD/ShiLtJ m 34.36 0.43932   5 0.19647 0.0128 33.8, 34.9 -1.16
NZO/HlLtJ f 34.02 1.9614   5 0.87715 0.0577 30.7, 35.6 -2.03
NZO/HlLtJ m 34.3 0.0   1   0.0 0.0 34.3, 34.3 -1.24
PWK/PhJ f 36.1 0.31623   4 0.15811 0.0088 35.8, 36.5 0.6
PWK/PhJ m 35.84 0.40373   5 0.18055 0.0113 35.2, 36.2 0.58
WSB/EiJ f 37.067 0.46188   3 0.26667 0.0125 36.8, 37.6 1.82
WSB/EiJ m 36.24 0.64265   5 0.2874 0.0177 35.2, 36.8 1.05


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 35.56 0.2229881565 36.0074584718 35.1125415282
129S1/SvImJ m 36.15 0.3525752329 36.8574939647 35.4425060353
A/J f 35.625 0.2493083381 36.1252737801 35.1247262199
A/J m 35.38 0.2229881565 35.8274584718 34.9325415282
C57BL/6J f 35.4666666667 0.2878764722 36.0443330699 34.8890002635
C57BL/6J m 34.2 0.2493083381 34.7002737801 33.6997262199
CAST/EiJ f 35.7 0.2229881565 36.1474584718 35.2525415282
CAST/EiJ m 36.15 0.3525752329 36.8574939647 35.4425060353
DBA/2J f 35.78 0.2229881565 36.2274584718 35.3325415282
DBA/2J m 35.5 0.2229881565 35.9474584718 35.0525415282
NOD/ShiLtJ f 35.3333333333 0.2035594056 35.7418051643 34.9248615024
NOD/ShiLtJ m 34.36 0.2229881565 34.8074584718 33.9125415282
PWK/PhJ f 36.1 0.2493083381 36.6002737801 35.5997262199
PWK/PhJ m 35.84 0.2229881565 36.2874584718 35.3925415282
WSB/EiJ f 37.0666666667 0.2878764722 37.6443330699 36.4890002635
WSB/EiJ m 36.24 0.2229881565 36.6874584718 35.7925415282


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 35.855 0.2085863208 36.2735590741 35.4364409259
A/J both 35.5025 0.1672411174 35.8380938539 35.1669061461
C57BL/6J both 34.8333333333 0.1904123884 35.2154237442 34.4512429224
CAST/EiJ both 35.925 0.2085863208 36.3435590741 35.5064409259
DBA/2J both 35.64 0.1576764376 35.9564009197 35.3235990803
NOD/ShiLtJ both 34.8466666667 0.1509636956 35.1495974841 34.5437358492
PWK/PhJ both 35.97 0.1672411174 36.3055938539 35.6344061461
WSB/EiJ both 36.6533333333 0.1820690674 37.0186816457 36.287985021




  GWAS USING LINEAR MIXED MODELS