Project measure / variable:   Auwerx2   temp_t0_HFD

ID, description, units MPD:114608   temp_t0_HFD   body temperature (rectal) in cold (4°C) room, 0h exposed to cold   [°C]  HFD  
Data set, strains Auwerx2   inbred w/CC8   9 strains     sex: both     age: 18wks
Procedure body temperature
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  STRAIN COMPARISON PLOT
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Auwerx2 - body temperature (rectal) in cold (4°C) room, 0h exposed to cold HFD



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested9 strains9 strains
Mean of the strain means36.509   °C 35.747   °C
Median of the strain means36.32   °C 35.9   °C
SD of the strain means± 0.9517 ± 0.91602
Coefficient of variation (CV)0.0261 0.0256
Min–max range of strain means35.64   –   38.833   °C 33.9   –   36.98   °C
Mean sample size per strain4.4   mice 3.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 5.7686 5.7686 32.4305 < 0.0001
strain 7 25.5155 3.6451 20.4923 < 0.0001
sex:strain 7 9.0763 1.2966 7.2895 < 0.0001
Residuals 52 9.2495 0.1779


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 36.32 0.22804   5 0.10198 0.0063 36.1, 36.7 -0.2
129S1/SvImJ m 36.4 0.28284   2   0.2 0.0078 36.2, 36.6 0.71
A/J f 35.675 0.3594   4 0.1797 0.0101 35.2, 36.0 -0.88
A/J m 35.34 0.2881   5 0.12884 0.0082 35.0, 35.7 -0.44
C57BL/6J f 36.6 0.4   3 0.23094 0.0109 36.2, 37.0 0.1
C57BL/6J m 35.8 0.57155   4 0.28577 0.016 35.2, 36.5 0.06
CAST/EiJ f 36.08 0.08367   5 0.03742 0.0023 36.0, 36.2 -0.45
CAST/EiJ m 35.9 0.28284   2   0.2 0.0079 35.7, 36.1 0.17
DBA/2J f 36.62 0.65345   5 0.29223 0.0178 36.0, 37.5 0.12
DBA/2J m 35.94 0.51769   5 0.23152 0.0144 35.3, 36.5 0.21
NOD/ShiLtJ f 36.667 0.38816   6 0.15846 0.0106 36.0, 37.0 0.17
NOD/ShiLtJ m 34.98 0.22804   5 0.10198 0.0065 34.7, 35.3 -0.84
NZO/HlLtJ f 35.64 0.35071   5 0.15684 0.0098 35.3, 36.2 -0.91
NZO/HlLtJ m 33.9 0.0   1   0.0 0.0 33.9, 33.9 -2.02
PWK/PhJ f 36.15 0.19149   4 0.09574 0.0053 36.0, 36.4 -0.38
PWK/PhJ m 36.48 0.19235   5 0.08602 0.0053 36.2, 36.7 0.8
WSB/EiJ f 38.833 0.15275   3 0.08819 0.0039 38.7, 39.0 2.44
WSB/EiJ m 36.98 0.83487   5 0.37336 0.0226 35.7, 37.7 1.35


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 36.32 0.1886133611 36.6984803985 35.9415196015
129S1/SvImJ m 36.4 0.2982239092 36.9984300545 35.8015699455
A/J f 35.675 0.2108761485 36.0981539496 35.2518460504
A/J m 35.34 0.1886133611 35.7184803985 34.9615196015
C57BL/6J f 36.6 0.2434988022 37.0886160934 36.1113839066
C57BL/6J m 35.8 0.2108761485 36.2231539496 35.3768460504
CAST/EiJ f 36.08 0.1886133611 36.4584803985 35.7015196015
CAST/EiJ m 35.9 0.2982239092 36.4984300545 35.3015699455
DBA/2J f 36.62 0.1886133611 36.9984803985 36.2415196015
DBA/2J m 35.94 0.1886133611 36.3184803985 35.5615196015
NOD/ShiLtJ f 36.6666666667 0.1721796542 37.0121704197 36.3211629136
NOD/ShiLtJ m 34.98 0.1886133611 35.3584803985 34.6015196015
PWK/PhJ f 36.15 0.2108761485 36.5731539496 35.7268460504
PWK/PhJ m 36.48 0.1886133611 36.8584803985 36.1015196015
WSB/EiJ f 38.8333333333 0.2434988022 39.3219494268 38.3447172399
WSB/EiJ m 36.98 0.1886133611 37.3584803985 36.6015196015


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 36.36 0.176431644 36.7140359947 36.0059640053
A/J both 35.5075 0.1414600209 35.7913602989 35.2236397011
C57BL/6J both 36.2 0.1610593188 36.5231891675 35.8768108325
CAST/EiJ both 35.99 0.176431644 36.3440359947 35.6359640053
DBA/2J both 36.28 0.1333697867 36.5476260563 36.0123739437
NOD/ShiLtJ both 35.8233333333 0.1276918491 36.0795657744 35.5671008923
PWK/PhJ both 36.315 0.1414600209 36.5988602989 36.0311397011
WSB/EiJ both 37.9066666667 0.1540021645 38.215694618 37.5976387153




  GWAS USING LINEAR MIXED MODELS