Project measure / variable:   Auwerx2   temp_t0_CD

ID, description, units MPD:114607   temp_t0_CD   body temperature (rectal) in cold (4°C) room, 0h exposed to cold   [°C]  CD  
Data set, strains Auwerx2   inbred w/CC8   9 strains     sex: both     age: 18wks
Procedure body temperature
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  STRAIN COMPARISON PLOT
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Auwerx2 - body temperature (rectal) in cold (4°C) room, 0h exposed to cold CD



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested9 strains9 strains
Mean of the strain means36.004   °C 36.309   °C
Median of the strain means36.033   °C 36.4   °C
SD of the strain means± 0.62086 ± 0.92017
Coefficient of variation (CV)0.0172 0.0253
Min–max range of strain means35.186   –   37.2   °C 34.8   –   38.04   °C
Mean sample size per strain4.4   mice 4.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 4.8372 4.8372 11.1699 0.0014
strain 7 22.3307 3.1901 7.3664 < 0.0001
sex:strain 7 19.486 2.7837 6.428 < 0.0001
Residuals 63 27.2827 0.4331


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 35.58 0.08367   5 0.03742 0.0024 35.5, 35.7 -0.68
129S1/SvImJ m 35.88 0.43243   5 0.19339 0.0121 35.2, 36.3 -0.47
A/J f 35.52 0.46043   5 0.20591 0.013 35.0, 36.2 -0.78
A/J m 35.52 0.21679   5 0.09695 0.0061 35.3, 35.8 -0.86
C57BL/6J f 35.56 0.11402   5 0.05099 0.0032 35.4, 35.7 -0.71
C57BL/6J m 37.1 0.48477   5 0.21679 0.0131 36.3, 37.6 0.86
CAST/EiJ f 37.2 0.0   1   0.0 0.0 37.2, 37.2 1.93
CAST/EiJ m 36.4 0.2   3 0.11547 0.0055 36.2, 36.6 0.1
DBA/2J f 36.54 0.20736   5 0.09274 0.0057 36.2, 36.7 0.86
DBA/2J m 36.16 0.4669   5 0.20881 0.0129 35.7, 36.8 -0.16
NOD/ShiLtJ f 35.186 1.3372   7 0.50541 0.038 32.2, 36.0 -1.32
NOD/ShiLtJ m 36.48 0.249   5 0.11136 0.0068 36.3, 36.9 0.19
NZO/HlLtJ f 36.175 0.66521   4 0.3326 0.0184 35.4, 37.0 0.28
NZO/HlLtJ m 34.8 0.886   5 0.39623 0.0255 33.5, 36.0 -1.64
PWK/PhJ f 36.24 0.60663   5 0.27129 0.0167 35.5, 36.9 0.38
PWK/PhJ m 36.4 0.51478   5 0.23022 0.0141 35.5, 36.8 0.1
WSB/EiJ f 36.033 1.4742   3 0.85114 0.0409 34.9, 37.7 0.05
WSB/EiJ m 38.04 0.52726   5 0.2358 0.0139 37.1, 38.3 1.88


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 35.58 0.2942989415 36.1681095064 34.9918904936
129S1/SvImJ m 35.88 0.2942989415 36.4681095064 35.2918904936
A/J f 35.52 0.2942989415 36.1081095064 34.9318904936
A/J m 35.52 0.2942989415 36.1081095064 34.9318904936
C57BL/6J f 35.56 0.2942989415 36.1481095064 34.9718904936
C57BL/6J m 37.1 0.2942989415 37.6881095064 36.5118904936
DBA/2J f 36.54 0.2942989415 37.1281095064 35.9518904936
DBA/2J m 36.16 0.2942989415 36.7481095064 35.5718904936
NOD/ShiLtJ f 35.1857142857 0.2487280026 35.6827575373 34.6886710341
NOD/ShiLtJ m 36.48 0.2942989415 37.0681095064 35.8918904936
NZO/HlLtJ f 36.175 0.3290362195 36.8325264173 35.5174735827
NZO/HlLtJ m 34.8 0.2942989415 35.3881095064 34.2118904936
PWK/PhJ f 36.24 0.2942989415 36.8281095064 35.6518904936
PWK/PhJ m 36.4 0.2942989415 36.9881095064 35.8118904936
WSB/EiJ f 36.0333333333 0.3799382997 36.7925794414 35.2740872253
WSB/EiJ m 38.04 0.2942989415 38.6281095064 37.4518904936


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 35.73 0.2081007772 36.1458562201 35.3141437799
A/J both 35.52 0.2081007772 35.9358562201 35.1041437799
C57BL/6J both 36.33 0.2081007772 36.7458562201 35.9141437799
DBA/2J both 36.35 0.2081007772 36.7658562201 35.9341437799
NOD/ShiLtJ both 35.8328571429 0.1926638823 36.21786519 35.4478490957
NZO/HlLtJ both 35.4875 0.2207242061 35.9285821298 35.0464178702
PWK/PhJ both 36.32 0.2081007772 36.7358562201 35.9041437799
WSB/EiJ both 37.0366666667 0.2402940795 37.5168560679 36.5564772655




  GWAS USING LINEAR MIXED MODELS