Project measure / variable:   Auwerx2   bw_20wks_HFD

ID, description, units MPD:114556   bw_20wks_HFD   body weight at 20 wks of age   [g]  HFD  
Data set, strains Auwerx2   inbred w/CC8   9 strains     sex: both     age: 20wks
Procedure body weight
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  STRAIN COMPARISON PLOT
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Auwerx2 - body weight at 20 wks of age HFD



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested9 strains9 strains
Mean of the strain means30.822   g 35.663   g
Median of the strain means25.055   g 34.12   g
SD of the strain means± 19.729 ± 17.074
Coefficient of variation (CV)0.6401 0.4788
Min–max range of strain means13.58   –   79.3   g 17.4   –   73.11   g
Mean sample size per strain4.4   mice 3.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 616.2269 616.2269 86.2953 < 0.0001
strain 7 4755.5002 679.3572 95.136 < 0.0001
sex:strain 7 345.8122 49.4017 6.9181 < 0.0001
Residuals 52 371.3271 7.1409


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 23.426 1.0597   5 0.47391 0.0452 22.37, 25.11 -0.37
129S1/SvImJ m 34.18 1.5415   2   1.09 0.0451 33.09, 35.27 -0.09
A/J f 24.138 2.0048   4 1.0024 0.0831 22.76, 27.04 -0.34
A/J m 28.444 1.4626   5 0.65411 0.0514 26.74, 30.24 -0.42
C57BL/6J f 29.42 4.1138   3 2.3751 0.1398 26.78, 34.16 -0.07
C57BL/6J m 46.707 3.6087   4 1.8043 0.0773 41.37, 48.97 0.65
CAST/EiJ f 13.706 0.93289   5 0.4172 0.0681 12.79, 15.18 -0.87
CAST/EiJ m 18.305 1.9304   2   1.365 0.1055 16.94, 19.67 -1.02
DBA/2J f 36.992 4.2807   5 1.9144 0.1157 31.93, 41.95 0.31
DBA/2J m 41.864 3.4148   5 1.5271 0.0816 38.4, 47.32 0.36
NOD/ShiLtJ f 31.777 3.337   6 1.3623 0.105 29.59, 38.4 0.05
NOD/ShiLtJ m 34.12 1.5143   5 0.6772 0.0444 33.0, 36.62 -0.09
NZO/HlLtJ f 79.3 2.4123   5 1.0788 0.0304 76.62, 82.37 2.46
NZO/HlLtJ m 73.11 0.0   1   0.0 0.0 73.11, 73.11 2.19
PWK/PhJ f 25.055 1.4907   4 0.74535 0.0595 23.75, 27.14 -0.29
PWK/PhJ m 26.838 4.1071   5 1.8367 0.153 21.57, 31.58 -0.52
WSB/EiJ f 13.58 0.58796   3 0.33946 0.0433 12.91, 14.01 -0.87
WSB/EiJ m 17.4 1.0124   5 0.45277 0.0582 16.4, 18.8 -1.07


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 23.426 1.1950652916 25.8240739493 21.0279260507
129S1/SvImJ m 34.18 1.8895641371 37.9716878387 30.3883121613
A/J f 24.1375 1.3361236148 26.8186281829 21.4563718171
A/J m 28.444 1.1950652916 30.8420739493 26.0459260507
C57BL/6J f 29.42 1.5428226574 32.5159001562 26.3240998438
C57BL/6J m 46.7075 1.3361236148 49.3886281829 44.0263718171
CAST/EiJ f 13.706 1.1950652916 16.1040739493 11.3079260507
CAST/EiJ m 18.305 1.8895641371 22.0966878387 14.5133121613
DBA/2J f 36.992 1.1950652916 39.3900739493 34.5939260507
DBA/2J m 41.864 1.1950652916 44.2620739493 39.4659260507
NOD/ShiLtJ f 31.7766666667 1.0909403632 33.965798661 29.5875346723
NOD/ShiLtJ m 34.12 1.1950652916 36.5180739493 31.7219260507
PWK/PhJ f 25.055 1.3361236148 27.7361281829 22.3738718171
PWK/PhJ m 26.838 1.1950652916 29.2360739493 24.4399260507
WSB/EiJ f 13.58 1.5428226574 16.6759001562 10.4840998438
WSB/EiJ m 17.4 1.1950652916 19.7980739493 15.0019260507


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 28.803 1.117881219 31.0461927766 26.5598072234
A/J both 26.29075 0.8962989687 28.089305462 24.492194538
C57BL/6J both 38.06375 1.0204812671 40.1114954743 36.0160045257
CAST/EiJ both 16.0055 1.117881219 18.2486927766 13.7623072234
DBA/2J both 39.428 0.8450387717 41.1236943513 37.7323056487
NOD/ShiLtJ both 32.9483333333 0.8090630271 34.5718370718 31.3248295949
PWK/PhJ both 25.9465 0.8962989687 27.745055462 24.147944538
WSB/EiJ both 15.49 0.9757667246 17.4480191804 13.5319808196




  GWAS USING LINEAR MIXED MODELS