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Project measure / variable:   Auwerx2   bw_10wks_HFD

ID, description, units MPD:114536   bw_10wks_HFD   body weight at 10 wks of age   [g]  HFD  
Data set, strains Auwerx2   inbred w/CC8   9 strains     sex: both     age: 10wks
Procedure body weight
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  STRAIN COMPARISON PLOT
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Auwerx2 - body weight at 10 wks of age HFD



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested9 strains9 strains
Mean of the strain means23.182   g 28.78   g
Median of the strain means20.633   g 29.35   g
SD of the strain means± 11.279 ± 13.145
Coefficient of variation (CV)0.4866 0.4568
Min–max range of strain means12.788   –   50.63   g 14.64   –   58.97   g
Mean sample size per strain4.4   mice 3.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 413.8647 413.8647 100.9002 < 0.0001
strain 7 2047.7376 292.5339 71.3197 < 0.0001
sex:strain 7 136.3147 19.4735 4.7476 0.0004
Residuals 52 213.2897 4.1017


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 21.53 1.8909   5 0.84565 0.0878 19.14, 23.59 -0.15
129S1/SvImJ m 30.61 0.91924   2   0.65 0.03 29.96, 31.26 0.14
A/J f 20.633 1.4286   4 0.71429 0.0692 19.57, 22.71 -0.23
A/J m 25.604 1.4442   5 0.64585 0.0564 23.3, 26.91 -0.24
C57BL/6J f 20.427 0.53267   3 0.30754 0.0261 20.08, 21.04 -0.24
C57BL/6J m 29.527 1.6553   4 0.82766 0.0561 28.05, 31.86 0.06
CAST/EiJ f 12.788 0.92829   5 0.41514 0.0726 11.57, 13.8 -0.92
CAST/EiJ m 15.335 0.44548   2   0.315 0.029 15.02, 15.65 -1.02
DBA/2J f 24.866 1.7032   5 0.7617 0.0685 22.61, 27.18 0.15
DBA/2J m 33.514 3.7333   5 1.6696 0.1114 28.47, 38.29 0.36
NOD/ShiLtJ f 26.503 3.2299   6 1.3186 0.1219 22.2, 31.8 0.29
NOD/ShiLtJ m 29.35 1.4647   5 0.65502 0.0499 27.97, 31.34 0.04
NZO/HlLtJ f 50.63 2.5963   5 1.1611 0.0513 48.29, 54.88 2.43
NZO/HlLtJ m 58.97 0.0   1   0.0 0.0 58.97, 58.97 2.3
PWK/PhJ f 18.045 2.2311   4 1.1156 0.1236 15.13, 20.56 -0.46
PWK/PhJ m 21.466 2.4631   5 1.1015 0.1147 18.14, 25.03 -0.56
WSB/EiJ f 13.217 0.76742   3 0.44307 0.0581 12.35, 13.81 -0.88
WSB/EiJ m 14.64 0.83181   5 0.37199 0.0568 13.75, 15.71 -1.08


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 21.53 0.9057290448 23.347478294 19.712521706
129S1/SvImJ m 30.61 1.4320833622 33.4836855034 27.7363144966
A/J f 20.6325 1.0126358567 22.6645025065 18.6004974935
A/J m 25.604 0.9057290448 27.421478294 23.786521706
C57BL/6J f 20.4266666667 1.1692911689 22.7730210549 18.0803122785
C57BL/6J m 29.5275 1.0126358567 31.5595025065 27.4954974935
CAST/EiJ f 12.788 0.9057290448 14.605478294 10.970521706
CAST/EiJ m 15.335 1.4320833622 18.2086855034 12.4613144966
DBA/2J f 24.866 0.9057290448 26.683478294 23.048521706
DBA/2J m 33.514 0.9057290448 35.331478294 31.696521706
NOD/ShiLtJ f 26.5033333333 0.8268137147 28.1624564323 24.8442102344
NOD/ShiLtJ m 29.35 0.9057290448 31.167478294 27.532521706
PWK/PhJ f 18.045 1.0126358567 20.0770025065 16.0129974935
PWK/PhJ m 21.466 0.9057290448 23.283478294 19.648521706
WSB/EiJ f 13.2166666667 1.1692911689 15.5630210549 10.8703122785
WSB/EiJ m 14.64 0.9057290448 16.457478294 12.822521706


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 26.07 0.8472319427 27.770095271 24.369904729
A/J both 23.11825 0.6792967836 24.4813587205 21.7551412795
C57BL/6J both 24.9770833333 0.7734134108 26.529050883 23.4251157836
CAST/EiJ both 14.0615 0.8472319427 15.761595271 12.361404729
DBA/2J both 29.19 0.6404471495 30.4751512263 27.9048487737
NOD/ShiLtJ both 27.9266666667 0.613181462 29.1571052883 26.696228045
PWK/PhJ both 19.7555 0.6792967836 21.1186087205 18.3923912795
WSB/EiJ both 13.9283333333 0.7395246683 15.4122981463 12.4443685204




  GWAS USING LINEAR MIXED MODELS