Project measure / variable:   Project1061   immediate_nicotine

ID, description, units MPD:113868   immediate_nicotine   immediate   [%]  nicotine  
Data set, strains Project1061   BXD w/par   31 strains     sex: both
Procedure fear conditioning test
Ontology mappings

  STRAIN COMPARISON PLOT
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Project1061 - immediate nicotine



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested31 strains31 strains
Mean of the strain means9.3683   % 13.279   %
Median of the strain means7.2917   % 8.3334   %
SD of the strain means± 8.5603 ± 13.649
Coefficient of variation (CV)0.9138 1.0279
Min–max range of strain means0.0   –   32.291   % 0.0   –   47.916   %
Mean sample size per strain8.1   mice 8.3   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 1834.2163 1834.2163 8.2164 0.0043
strain 30 56179.3063 1872.6435 8.3885 < 0.0001
sex:strain 30 8626.1907 287.5397 1.288 0.1445
Residuals 446 99564.3734 223.2385


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
BXD102/RwwJ f 5.2084 9.8978   8 3.4994 1.9004 -0.49
BXD102/RwwJ m 8.3333 11.785   8 4.1666 1.4142 -0.36
BXD124/RwwJ f 12.5 22.714   8 8.0306 1.8171 0.37
BXD124/RwwJ m 19.792 24.776   8 8.7595 1.2518 0.48
BXD13/TyJ f 12.5 11.785   8 4.1666 0.9428 0.37
BXD13/TyJ m 11.458 9.8978   8 3.4994 0.8638 -0.13
BXD154/RwwJ f 6.25 12.4   8 4.3842 1.9841 -0.36
BXD154/RwwJ m 8.3334 7.217   9 2.4057 0.866 -0.36
BXD161/RwwJ f 0.0 0.0   8 0.0 None -1.09
BXD161/RwwJ m 3.125 4.3129   8 1.5248 1.3801 -0.74
BXD18/TyJ f 7.2917 12.148   8 4.2949 1.666 -0.24
BXD18/TyJ m 2.7778 5.8927   9 1.9642 2.1213 -0.77
BXD21/TyJ f 25.0 29.88   8 10.564 1.1952 1.83
BXD21/TyJ m 20.833 19.92   8 7.0426 0.9562 0.55
BXD31/TyJ f 9.3746 20.136   8 7.1192 2.1479 0.0
BXD31/TyJ m 11.458 17.783   8 6.2871 1.5519 -0.13
BXD32/TyJ f 14.583 15.905   8 5.6234 1.0906 0.61
BXD32/TyJ m 27.381 28.348   7 10.715 1.0353 1.03
BXD33/TyJ f 32.291 20.137   8 7.1194 0.6236 2.68
BXD33/TyJ m 37.121 30.36   11 9.1539 0.8179 1.75
BXD34/TyJ f 9.1666 9.9768   10 3.1549 1.0884 -0.02
BXD34/TyJ m 15.625 12.148   8 4.2949 0.7775 0.17
BXD38/TyJ f 25.0 18.161   9 6.0537 0.7265 1.83
BXD38/TyJ m 32.292 23.754   8 8.3982 0.7356 8.3333, 66.67 1.39
BXD39/TyJ f 19.792 17.783   8 6.2871 0.8985 1.22
BXD39/TyJ m 47.916 15.268   8 5.3982 0.3186 25.0, 75.0 2.54
BXD40/TyJ f 2.0834 5.8927   8 2.0834 2.8284 -0.85
BXD40/TyJ m 3.125 6.2003   8 2.1921 1.9841 -0.74
BXD45/RwwJ f 2.0834 5.8927   8 2.0834 2.8284 -0.85
BXD45/RwwJ m 3.125 6.2003   8 2.1921 1.9841 -0.74
BXD48a/RwwJ f 9.3751 14.391   8 5.0879 1.535 0.0
BXD48a/RwwJ m 12.5 8.9087   8 3.1497 0.7127 -0.06
BXD55/RwwJ f 0.0 0.0   8 0.0 None -1.09
BXD55/RwwJ m 0.0 0.0   9 0.0 None -0.97
BXD56/RwwJ f 21.875 24.373   8 8.6171 1.1142 1.46
BXD56/RwwJ m 28.125 26.703   8 9.4409 0.9494 1.09
BXD64/RwwJ f 2.0833 3.8576   8 1.3639 1.8516 -0.85
BXD64/RwwJ m 8.3334 9.9603   8 3.5215 1.1952 -0.36
BXD67/RwwJ f 2.0833 3.8576   8 1.3639 1.8516 -0.85
BXD67/RwwJ m 1.0417 2.9463   8 1.0417 2.8284 -0.9
BXD73a/RwwJ f 8.3334 9.9603   8 3.5215 1.1952 -0.12
BXD73a/RwwJ m 5.0 5.8268   10 1.8426 1.1654 -0.61
BXD74/RwwJ f 8.3334 8.9088   8 3.1497 1.069 -0.12
BXD74/RwwJ m 12.5 22.714   8 8.0306 1.8171 -0.06
BXD78 f 6.25 14.605   8 5.1635 2.3367 -0.36
BXD78 m 23.958 27.972   8 9.8896 1.1675 0.78
BXD84/RwwJ f 4.1666 4.4543   8 1.5748 1.069 -0.61
BXD84/RwwJ m 13.542 19.889   8 7.0319 1.4688 0.02
BXD85/RwwJ f 1.0417 2.9463   8 1.0417 2.8284 -0.97
BXD85/RwwJ m 2.0833 3.8576   8 1.3639 1.8516 -0.82
BXD89/RwwJ f 1.0417 2.9463   8 1.0417 2.8284 -0.97
BXD89/RwwJ m 0.0 0.0   8 0.0 None -0.97
BXD90/RwwJ f 2.0834 5.8927   8 2.0834 2.8284 -0.85
BXD90/RwwJ m 0.0 0.0   8 0.0 None -0.97
BXD98/RwwJ f 1.0417 2.9463   8 1.0417 2.8284 -0.97
BXD98/RwwJ m 1.0417 2.9463   8 1.0417 2.8284 -0.9
BXD99/RwwJ f 14.583 22.16   8 7.8348 1.5196 0.61
BXD99/RwwJ m 0.83333 2.6352   10 0.83333 3.1623 -0.91
C57BL/6J f 5.2084 6.2003   8 2.1921 1.1904 -0.49
C57BL/6J m 4.1668 7.7153   8 2.7278 1.8516 -0.67
DBA/2J f 19.792 14.732   8 5.2084 0.7443 8.3333, 41.667 1.22
DBA/2J m 45.833 28.868   8 10.206 0.6298 8.3333, 75.0 2.39


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
BXD102/RwwJ f 5.208375 5.2825006565 15.5900587311 -5.1733087311
BXD102/RwwJ m 8.333325 5.2825006565 18.7150087311 -2.0483587311
BXD124/RwwJ f 12.50045 5.2825006565 22.8821337311 2.1187662689
BXD124/RwwJ m 19.7917 5.2825006565 30.1733837311 9.4100162689
BXD13/TyJ f 12.4999875 5.2825006565 22.8816712311 2.1183037689
BXD13/TyJ m 11.4583625 5.2825006565 21.8400462311 1.0766787689
BXD154/RwwJ f 6.25 5.2825006565 16.6316837311 -4.1316837311
BXD154/RwwJ m 8.3334333333 4.9803893811 18.1213786219 -1.4545119552
BXD161/RwwJ f 0.0 5.2825006565 10.3816837311 -10.3816837311
BXD161/RwwJ m 3.1249875 5.2825006565 13.5066712311 -7.2566962311
BXD18/TyJ f 7.2916625 5.2825006565 17.6733462311 -3.0900212311
BXD18/TyJ m 2.7778111111 4.9803893811 12.5657563997 -7.0101341774
BXD21/TyJ f 24.9995375 5.2825006565 35.3812212311 14.6178537689
BXD21/TyJ m 20.8329125 5.2825006565 31.2145962311 10.4512287689
BXD31/TyJ f 9.374575 5.2825006565 19.7562587311 -1.0071087311
BXD31/TyJ m 11.458325 5.2825006565 21.8400087311 1.0766412689
BXD32/TyJ f 14.5834125 5.2825006565 24.9650962311 4.2017287689
BXD32/TyJ m 27.3814285714 5.6472307434 38.4799153199 16.2829418229
BXD33/TyJ f 32.2912875 5.2825006565 42.6729712311 21.9096037689
BXD33/TyJ m 37.1208090909 4.5049316964 45.9743387247 28.2672794571
BXD34/TyJ f 9.16665 4.7248122236 18.4523102175 -0.1190102175
BXD34/TyJ m 15.6249875 5.2825006565 26.0066712311 5.2433037689
BXD38/TyJ f 24.9995555556 4.9803893811 34.7875008441 15.211610267
BXD38/TyJ m 32.2916125 5.2825006565 42.6732962311 21.9099287689
BXD39/TyJ f 19.7917 5.2825006565 30.1733837311 9.4100162689
BXD39/TyJ m 47.91625 5.2825006565 58.2979337311 37.5345662689
BXD40/TyJ f 2.083375 5.2825006565 12.4650587311 -8.2983087311
BXD40/TyJ m 3.1250375 5.2825006565 13.5067212311 -7.2566462311
BXD45/RwwJ f 2.083375 5.2825006565 12.4650587311 -8.2983087311
BXD45/RwwJ m 3.1250375 5.2825006565 13.5067212311 -7.2566462311
BXD48a/RwwJ f 9.375075 5.2825006565 19.7567587311 -1.0066087311
BXD48a/RwwJ m 12.500025 5.2825006565 22.8817087311 2.1183412689
BXD55/RwwJ f 0.0 5.2825006565 10.3816837311 -10.3816837311
BXD55/RwwJ m 0.0 4.9803893811 9.7879452885 -9.7879452885
BXD56/RwwJ f 21.8754125 5.2825006565 32.2570962311 11.4937287689
BXD56/RwwJ m 28.1250375 5.2825006565 38.5067212311 17.7433537689
BXD64/RwwJ f 2.083325 5.2825006565 12.4650087311 -8.2983587311
BXD64/RwwJ m 8.3334125 5.2825006565 18.7150962311 -2.0482712311
BXD67/RwwJ f 2.083325 5.2825006565 12.4650087311 -8.2983587311
BXD67/RwwJ m 1.0416625 5.2825006565 11.4233462311 -9.3400212311
BXD73a/RwwJ f 8.3334125 5.2825006565 18.7150962311 -2.0482712311
BXD73a/RwwJ m 5.00002 4.7248122236 14.2856802175 -4.2856402175
BXD74/RwwJ f 8.3333625 5.2825006565 18.7150462311 -2.0483212311
BXD74/RwwJ m 12.50045 5.2825006565 22.8821337311 2.1187662689
BXD78 f 6.2500375 5.2825006565 16.6317212311 -4.1316462311
BXD78 m 23.957875 5.2825006565 34.3395587311 13.5761912689
BXD84/RwwJ f 4.16665 5.2825006565 14.5483337311 -6.2150337311
BXD84/RwwJ m 13.541625 5.2825006565 23.9233087311 3.1599412689
BXD85/RwwJ f 1.0416625 5.2825006565 11.4233462311 -9.3400212311
BXD85/RwwJ m 2.083325 5.2825006565 12.4650087311 -8.2983587311
BXD89/RwwJ f 1.0416625 5.2825006565 11.4233462311 -9.3400212311
BXD89/RwwJ m 0.0 5.2825006565 10.3816837311 -10.3816837311
BXD90/RwwJ f 2.083375 5.2825006565 12.4650587311 -8.2983087311
BXD90/RwwJ m 0.0 5.2825006565 10.3816837311 -10.3816837311
BXD98/RwwJ f 1.0416625 5.2825006565 11.4233462311 -9.3400212311
BXD98/RwwJ m 1.0416625 5.2825006565 11.4233462311 -9.3400212311
BXD99/RwwJ f 14.583325 5.2825006565 24.9650087311 4.2016412689
BXD99/RwwJ m 0.83333 4.7248122236 10.1189902175 -8.4523302175
C57BL/6J f 5.2083625 5.2825006565 15.5900462311 -5.1733212311
C57BL/6J m 4.16675 5.2825006565 14.5484337311 -6.2149337311
DBA/2J f 19.791775 5.2825006565 30.1734587311 9.4100912689
DBA/2J m 45.833325 5.2825006565 56.2150087311 35.4516412689


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
BXD102/RwwJ both 6.77085 3.7352920358 14.1118089664 -0.5701089664
BXD124/RwwJ both 16.146075 3.7352920358 23.4870339664 8.8051160336
BXD13/TyJ both 11.979175 3.7352920358 19.3201339664 4.6382160336
BXD154/RwwJ both 7.2917166667 3.6300513623 14.4258464325 0.1575869008
BXD161/RwwJ both 1.56249375 3.7352920358 8.9034527164 -5.7784652164
BXD18/TyJ both 5.0347368056 3.6300513623 12.1688665714 -2.0993929603
BXD21/TyJ both 22.916225 3.7352920358 30.2571839664 15.5752660336
BXD31/TyJ both 10.41645 3.7352920358 17.7574089664 3.0754910336
BXD32/TyJ both 20.9824205357 3.866394582 28.5810349686 13.3838061028
BXD33/TyJ both 34.7060482955 3.471283004 41.5281510517 27.8839455392
BXD34/TyJ both 12.39581875 3.5436091677 19.3600639131 5.4315735869
BXD38/TyJ both 28.6455840278 3.6300513623 35.7797137936 21.5114542619
BXD39/TyJ both 33.853975 3.7352920358 41.1949339664 26.5130160336
BXD40/TyJ both 2.60420625 3.7352920358 9.9451652164 -4.7367527164
BXD45/RwwJ both 2.60420625 3.7352920358 9.9451652164 -4.7367527164
BXD48a/RwwJ both 10.93755 3.7352920358 18.2785089664 3.5965910336
BXD55/RwwJ both 0.0 3.6300513623 7.1341297659 -7.1341297659
BXD56/RwwJ both 25.000225 3.7352920358 32.3411839664 17.6592660336
BXD64/RwwJ both 5.20836875 3.7352920358 12.5493277164 -2.1325902164
BXD67/RwwJ both 1.56249375 3.7352920358 8.9034527164 -5.7784652164
BXD73a/RwwJ both 6.66671625 3.5436091677 13.6309614131 -0.2975289131
BXD74/RwwJ both 10.41690625 3.7352920358 17.7578652164 3.0759472836
BXD78 both 15.10395625 3.7352920358 22.4449152164 7.7629972836
BXD84/RwwJ both 8.8541375 3.7352920358 16.1950964664 1.5131785336
BXD85/RwwJ both 1.56249375 3.7352920358 8.9034527164 -5.7784652164
BXD89/RwwJ both 0.52083125 3.7352920358 7.8617902164 -6.8201277164
BXD90/RwwJ both 1.0416875 3.7352920358 8.3826464664 -6.2992714664
BXD98/RwwJ both 1.0416625 3.7352920358 8.3826214664 -6.2992964664
BXD99/RwwJ both 7.7083275 3.5436091677 14.6725726631 0.7440823369
C57BL/6J both 4.68755625 3.7352920358 12.0285152164 -2.6534027164
DBA/2J both 32.81255 3.7352920358 40.1535089664 25.4715910336




  GWAS USING LINEAR MIXED MODELS