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Project measure / variable:   CSNA03   trial_init_latency_in_rev_JAX

ID, description, units MPD:110474   trial_init_latency_in_rev_JAX   mean latency (across trials) between illumination of central hole and initiation of trial (reversal learning assay), founders   [centiseconds/n]  reversal  
Data set, strains CSNA03   inbred w/CC8   8 strains     sex: both     age:
Procedure operant conditioning chamber
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  STRAIN COMPARISON PLOT
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CSNA03 - mean latency (across trials) between illumination of central hole and initiation of trial (reversal learning assay), founders reversal



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means534.7   centiseconds/n 570.9   centiseconds/n
Median of the strain means471.1   centiseconds/n 526.8   centiseconds/n
SD of the strain means± 378.0 ± 219.6
Coefficient of variation (CV)0.707 0.3847
Min–max range of strain means193.6   –   1365.0   centiseconds/n 316.7   –   915.5   centiseconds/n
Mean sample size per strain7.6   mice 6.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 164266.1031 164266.1031 0.8934 0.3468
strain 7 5105465.9465 729352.2781 3.9667 0.0007
sex:strain 7 1303478.6035 186211.2291 1.0127 0.427
Residuals 100 18386834.999 183868.35


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ f 1365.0 1287.0   3 743.3 0.9434 230.2, 2764.0 2.2
129S1/SvImJ m 915.5 643.7   4 321.8 0.7031 222.0, 1692.0 1.57
A/J f 502.3 237.6   6 97.01 0.4731 256.1, 895.3 -0.09
A/J m 852.4 883.9   5 395.3 1.0369 241.6, 2321.0 1.28
C57BL/6J f 439.8 193.8   14 51.8 0.4407 136.0, 771.2 -0.25
C57BL/6J m 443.3 221.5   11 66.8 0.4998 99.91, 703.8 -0.58
CAST/EiJ f 193.6 75.27   10 23.804 0.3888 97.54, 296.8 -0.9
CAST/EiJ m 316.7 211.5   8 74.77 0.6678 95.8, 792.0 -1.16
NOD/ShiLtJ f 243.3 178.3   8 63.03 0.7328 49.208, 548.9 -0.77
NOD/ShiLtJ m 347.0 318.1   11 95.92 0.917 57.89, 1179.0 -1.02
NZO/HlLtJ f 533.6 539.6   3 311.6 1.0113 173.2, 1154.0 0.0
NZO/HlLtJ m 516.5 535.1   2   378.4 1.0358 138.2, 894.9 -0.25
PWK/PhJ f 279.5 147.1   9 49.032 0.5264 79.35, 497.6 -0.68
PWK/PhJ m 638.4 504.2   8 178.2 0.7897 63.46, 1388.0 0.31
WSB/EiJ f 720.4 750.7   8 265.4 1.0421 49.806, 2406.0 0.49
WSB/EiJ m 537.1 464.1   6 189.5 0.8642 150.6, 1416.0 -0.15


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ f 1364.7333333333 247.5670616148 1855.8993325016 873.567334165
129S1/SvImJ m 915.525 214.3993644987 1340.8872327549 490.1627672451
A/J f 502.2666666667 175.0563480662 849.5734753668 154.9598579665
A/J m 852.44 191.7646213407 1232.8955470004 471.9844529996
C57BL/6J f 439.7857142857 114.6012808423 667.1513914631 212.4200371083
C57BL/6J m 443.2554545455 129.2876813332 699.7585320065 186.7523770844
CAST/EiJ f 193.594 135.5980641417 462.616697224 -75.428697224
CAST/EiJ m 316.7 151.6032445191 617.4765192416 15.9234807584
NOD/ShiLtJ f 243.301 151.6032445191 544.0775192416 -57.4755192416
NOD/ShiLtJ m 346.9509090909 129.2876813332 603.453986552 90.4478316298
NZO/HlLtJ f 533.6 247.5670616148 1024.7659991683 42.4340008317
NZO/HlLtJ m 516.55 303.2064890382 1118.1030384833 -85.0030384833
PWK/PhJ f 279.4611111111 142.9329096658 563.0359329477 -4.1137107255
PWK/PhJ m 638.3825 151.6032445191 939.1590192416 337.6059807584
WSB/EiJ f 720.40075 151.6032445191 1021.1772692416 419.6242307584
WSB/EiJ m 537.1 175.0563480662 884.4068087002 189.7931912998


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ both 1140.1291666667 163.7502194609 1465.0049382291 815.2533951042
A/J both 677.3533333333 129.8252623685 934.9229562574 419.7837104093
C57BL/6J both 441.5205844156 86.3839656927 612.9039120071 270.1372568241
CAST/EiJ both 255.147 101.6985481063 456.914022918 53.379977082
NOD/ShiLtJ both 295.1259545455 99.6228491527 492.7748498587 97.4770592323
NZO/HlLtJ both 525.075 195.7189470845 913.375816651 136.774183349
PWK/PhJ both 458.9218055556 104.1793650564 665.6106986454 252.2329124657
WSB/EiJ both 628.750375 115.7888906016 858.472236115 399.028513885




  GWAS USING LINEAR MIXED MODELS