Project measure / variable:   CSNA03   reinstatement_inf_cc_s2

ID, description, units MPD:110423   reinstatement_inf_cc_s2   reinstatement, number of infusions (intravenous self administration), CC   [n]  session 2  
cocaine study
Data set, strains CSNA03   CC w/par   54 strains     sex: both     age:
Procedure operant conditioning chamber
Ontology mappings

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  STRAIN COMPARISON PLOT
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CSNA03 - reinstatement, number of infusions (intravenous self administration), CC session 2



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested52 strains51 strains
Mean of the strain means51.53   n 39.07   n
Median of the strain means46.25   n 39.0   n
SD of the strain means± 39.161 ± 23.532
Coefficient of variation (CV)0.76 0.6023
Min–max range of strain means0.0   –   159.7   n 0.0   –   114.9   n
Mean sample size per strain3.2   mice 3.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 12582.1316 12582.1316 8.5214 0.0038
strain 39 320984.4855 8230.3714 5.5741 < 0.0001
sex:strain 39 65186.2362 1671.442 1.132 0.2834
Residuals 240 354366.0186 1476.5251


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
A/J f 40.0 39.598   9 13.199 0.9899 1.0, 106.0 -0.29
A/J m 46.714 43.809   7 16.558 0.9378 0.32
C57BL/6J f 74.0 37.092   12 10.708 0.5012 14.0, 132.0 0.57
C57BL/6J m 40.385 29.89   13 8.29 0.7401 5.0, 121.0 0.06
CAST/EiJ f 92.0 0.0   1   0.0 0.0 92.0, 92.0 1.03
CAST/EiJ m 40.5 40.305   2   28.5 0.9952 12.0, 69.0 0.06
CC001/UncJ f 25.667 12.423   3 7.1725 0.484 18.0, 40.0 -0.66
CC001/UncJ m 44.75 32.108   4 16.054 0.7175 14.0, 79.0 0.24
CC002/UncJ f 159.7 100.4   3 57.94 0.6285 46.0, 236.0 2.76
CC002/UncJ m 58.5 17.678   2   12.5 0.3022 46.0, 71.0 0.83
CC003/UncJ f 29.0 8.4853   2   6.0 0.2926 23.0, 35.0 -0.58
CC003/UncJ m 7.75 5.1881   4 2.5941 0.6694 4.0, 15.0 -1.33
CC004/TauUncJ f 119.6 55.16   9 18.387 0.4614 23.0, 173.0 1.74
CC004/TauUncJ m 114.9 53.01   19 12.161 0.4611 36.0, 191.0 3.22
CC005/TauUncJ f 16.5 4.6547   4 2.3274 0.2821 10.0, 21.0 -0.89
CC005/TauUncJ m 13.0 2.8284   2   2.0 0.2176 11.0, 15.0 -1.11
CC006/TauUncJ f 39.5 0.70711   2   0.5 0.0179 39.0, 40.0 -0.31
CC006/TauUncJ m 70.0 97.58   2   69.0 1.394 1.0, 139.0 1.31
CC007/UncJ f 63.0 86.27   2   61.0 1.3693 2.0, 124.0 0.29
CC007/UncJ m 30.0 30.0   3 17.321 1.0 -0.39
CC008/GeniUncJ f 5.0 0.0   2   0.0 0.0 5.0, 5.0 -1.19
CC008/GeniUncJ m 41.5 12.021   2   8.5 0.2897 33.0, 50.0 0.1
CC009/UncJ f 59.0 56.51   3 32.624 0.9577 3.0, 116.0 0.19
CC009/UncJ m 13.333 21.385   3 12.347 1.6039 -1.09
CC011/UncJ f 76.33 28.042   3 16.19 0.3674 44.0, 94.0 0.63
CC011/UncJ m 35.0 10.583   3 6.1101 0.3024 23.0, 43.0 -0.17
CC012/GeniUncJ f 90.0 0.0   1   0.0 0.0 90.0, 90.0 0.98
CC012/GeniUncJ m 69.33 51.07   3 29.486 0.7366 11.0, 106.0 1.29
CC013/GeniUncJ f 79.33 54.99   3 31.751 0.6932 16.0, 115.0 0.71
CC013/GeniUncJ m 47.667 19.553   3 11.289 0.4102 26.0, 64.0 0.37
CC015/UncJ f 18.5 20.506   2   14.5 1.1084 4.0, 33.0 -0.84
CC015/UncJ m 46.0 0.0   1   0.0 0.0 46.0, 46.0 0.29
CC016/GeniUncJ f 54.5 68.59   2   48.5 1.2585 6.0, 103.0 0.08
CC016/GeniUncJ m 9.5 6.364   2   4.5 0.6699 5.0, 14.0 -1.26
CC017/UncJ f 17.0 9.1652   3 5.2915 0.5391 9.0, 27.0 -0.88
CC017/UncJ m 4.5 1.0   4 0.5 0.2222 4.0, 6.0 -1.47
CC018/UncJ f 99.33 78.69   3 45.432 0.7922 9.0, 153.0 1.22
CC018/UncJ m 81.0 15.116   5 6.7602 0.1866 61.0, 101.0 1.78
CC019/TauUncJ f 90.8 47.531   5 21.257 0.5235 24.0, 138.0 1.0
CC019/TauUncJ m 27.333 18.175   3 10.493 0.6649 7.0, 42.0 -0.5
CC020/GeniUncJ f 56.0 0.0   1   0.0 0.0 56.0, 56.0 0.11
CC023/GeniUncJ f 22.333 19.553   3 11.289 0.8755 2.0, 41.0 -0.75
CC023/GeniUncJ m 25.667 13.65   3 7.8811 0.5318 10.0, 35.0 -0.57
CC024/GeniUncJ f 24.0 33.941   2   24.0 1.4142 -0.7
CC024/GeniUncJ m 13.0 18.385   2   13.0 1.4142 -1.11
CC025/GeniUncJ f 63.0 70.71   2   50.0 1.1224 13.0, 113.0 0.29
CC025/GeniUncJ m 39.0 0.0   1   0.0 0.0 39.0, 39.0 0.0
CC026/GeniUncJ f 20.2 10.498   5 4.6947 0.5197 6.0, 32.0 -0.8
CC026/GeniUncJ m 20.333 8.3267   3 4.8074 0.4095 11.0, 27.0 -0.8
CC027/GeniUncJ f 64.25 69.12   4 34.558 1.0757 3.0, 139.0 0.32
CC027/GeniUncJ m 24.5 17.54   4 8.7702 0.7159 6.0, 44.0 -0.62
CC028/GeniUncJ f 69.0 28.925   4 14.463 0.4192 40.0, 108.0 0.45
CC028/GeniUncJ m 38.6 15.372   5 6.8746 0.3982 25.0, 62.0 -0.02
CC029/UncJ f 1.0 0.0   1   0.0 0.0 1.0, 1.0 -1.29
CC029/UncJ m 18.0 0.0   1   0.0 0.0 18.0, 18.0 -0.9
CC030/GeniUncJ f 52.5 74.25   2   52.5 1.4142 0.02
CC030/GeniUncJ m 65.5 36.062   2   25.5 0.5506 40.0, 91.0 1.12
CC032/GeniUncJ f 34.667 7.6376   3 4.4096 0.2203 28.0, 43.0 -0.43
CC032/GeniUncJ m 44.25 58.75   4 29.375 1.3277 4.0, 131.0 0.22
CC033/GeniUncJ f 19.0 0.0   1   0.0 0.0 19.0, 19.0 -0.83
CC033/GeniUncJ m 25.5 16.263   2   11.5 0.6378 14.0, 37.0 -0.58
CC035/UncJ f 18.667 10.97   3 6.3333 0.5877 10.0, 31.0 -0.84
CC035/UncJ m 55.0 49.497   2   35.0 0.9 20.0, 90.0 0.68
CC036/UncJ f 122.0 39.509   3 22.811 0.3238 93.0, 167.0 1.8
CC036/UncJ m 65.0 45.255   2   32.0 0.6962 33.0, 97.0 1.1
CC037/TauUncJ f 23.0 0.0   1   0.0 0.0 23.0, 23.0 -0.73
CC037/TauUncJ m 0.0 0.0   1   0.0 None -1.66
CC040/TauUncJ f 22.5 27.577   2   19.5 1.2257 3.0, 42.0 -0.74
CC040/TauUncJ m 57.0 1.4142   2   1.0 0.0248 56.0, 58.0 0.76
CC041/TauUncJ f 12.0 16.971   2   12.0 1.4142 -1.01
CC041/TauUncJ m 4.4167 8.2402   12 2.3788 1.8657 -1.47
CC043/GeniUncJ m 10.0 0.0   1   0.0 0.0 10.0, 10.0 -1.24
CC044/UncJ f 2.0 2.8284   2   2.0 1.4142 -1.26
CC044/UncJ m 38.0 45.255   2   32.0 1.1909 6.0, 70.0 -0.05
CC051/TauUncJ f 32.5 6.364   2   4.5 0.1958 28.0, 37.0 -0.49
CC051/TauUncJ m 35.667 23.352   3 13.482 0.6547 15.0, 61.0 -0.14
CC057/UncJ f 93.5 118.1   2   83.5 1.263 10.0, 177.0 1.07
CC057/UncJ m 22.0 7.0711   2   5.0 0.3214 17.0, 27.0 -0.73
CC059/TauUncJ f 153.0 91.21   4 45.607 0.5962 17.0, 209.0 2.59
CC059/TauUncJ m 48.0 5.2915   3 3.0551 0.1102 42.0, 52.0 0.38
CC060/UncJ m 43.0 0.0   1   0.0 0.0 43.0, 43.0 0.17
CC061/GeniUncJ f 88.0 63.64   2   45.0 0.7232 43.0, 133.0 0.93
CC061/GeniUncJ m 78.5 48.79   2   34.5 0.6215 44.0, 113.0 1.68
CC068/TauUncJ f 0.0 0.0   2   0.0 None -1.32
CC068/TauUncJ m 1.0 1.4142   2   1.0 1.4142 -1.62
CC074/UncJ f 8.0 0.0   1   0.0 0.0 8.0, 8.0 -1.11
CC074/UncJ m 41.0 0.0   1   0.0 0.0 41.0, 41.0 0.08
CC075/UncJ f 4.0 0.0   1   0.0 0.0 4.0, 4.0 -1.21
CC078/TauUncJ f 71.0 45.255   2   32.0 0.6374 39.0, 103.0 0.5
CC078/TauUncJ m 64.33 53.95   3 31.147 0.8386 19.0, 124.0 1.07
CC079/TauUncJ f 97.5 10.607   2   7.5 0.1088 90.0, 105.0 1.17
CC079/TauUncJ m 69.0 76.37   2   54.0 1.1068 15.0, 123.0 1.27
CC080/TauUncJ f 4.5 6.364   2   4.5 1.4142 -1.2
CC084/TauJ f 77.0 59.4   2   42.0 0.7714 35.0, 119.0 0.65
CC084/TauJ m 35.0 0.0   1   0.0 0.0 35.0, 35.0 -0.17
NOD/ShiLtJ f 28.182 32.034   11 9.6586 1.1367 2.0, 104.0 -0.6
NOD/ShiLtJ m 32.667 16.621   6 6.7856 0.5088 10.0, 53.0 -0.27
NZO/HlLtJ f 32.6 25.295   10 7.9989 0.7759 -0.48
NZO/HlLtJ m 31.3 15.945   10 5.0422 0.5094 6.0, 62.0 -0.33
PWK/PhJ f 58.86 25.635   7 9.689 0.4355 34.0, 88.0 0.19
PWK/PhJ m 57.5 20.695   6 8.4489 0.3599 23.0, 85.0 0.78
WSB/EiJ f 56.0 42.438   3 24.502 0.7578 7.0, 81.0 0.11
WSB/EiJ m 48.2 22.61   5 10.111 0.4691 14.0, 70.0 0.39


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J f 40.0 12.8085261424 65.2314853567 14.7685146433
A/J m 46.7142857143 14.5235035003 75.3241009126 18.104470516
C57BL/6J f 74.0 11.0925090244 95.8511072941 52.1488927059
C57BL/6J m 40.3846153846 10.6573379468 61.3784802023 19.390750567
CC001/UncJ f 25.6666666667 22.1850180487 69.368881255 -18.0355479216
CC001/UncJ m 44.75 19.2127892136 82.5972280351 6.9027719649
CC002/UncJ f 159.6666666667 22.1850180487 203.368881255 115.9644520784
CC002/UncJ m 58.5 27.1709870769 112.0240631855 4.9759368145
CC003/UncJ f 29.0 27.1709870769 82.5240631855 -24.5240631855
CC003/UncJ m 7.75 19.2127892136 45.5972280351 -30.0972280351
CC004/TauUncJ f 119.5555555556 12.8085261424 144.7870409123 94.3240701988
CC004/TauUncJ m 114.9473684211 8.8154322743 132.3128676103 97.5818692318
CC005/TauUncJ f 16.5 19.2127892136 54.3472280351 -21.3472280351
CC005/TauUncJ m 13.0 27.1709870769 66.5240631855 -40.5240631855
CC006/TauUncJ f 39.5 27.1709870769 93.0240631855 -14.0240631855
CC006/TauUncJ m 70.0 27.1709870769 123.5240631855 16.4759368145
CC007/UncJ f 63.0 27.1709870769 116.5240631855 9.4759368145
CC007/UncJ m 30.0 22.1850180487 73.7022145883 -13.7022145883
CC008/GeniUncJ f 5.0 27.1709870769 58.5240631855 -48.5240631855
CC008/GeniUncJ m 41.5 27.1709870769 95.0240631855 -12.0240631855
CC009/UncJ f 59.0 22.1850180487 102.7022145883 15.2977854117
CC009/UncJ m 13.3333333333 22.1850180487 57.0355479216 -30.368881255
CC011/UncJ f 76.3333333333 22.1850180487 120.0355479216 32.631118745
CC011/UncJ m 35.0 22.1850180487 78.7022145883 -8.7022145883
CC013/GeniUncJ f 79.3333333333 22.1850180487 123.0355479216 35.631118745
CC013/GeniUncJ m 47.6666666667 22.1850180487 91.368881255 3.9644520784
CC016/GeniUncJ f 54.5 27.1709870769 108.0240631855 0.9759368145
CC016/GeniUncJ m 9.5 27.1709870769 63.0240631855 -44.0240631855
CC017/UncJ f 17.0 22.1850180487 60.7022145883 -26.7022145883
CC017/UncJ m 4.5 19.2127892136 42.3472280351 -33.3472280351
CC018/UncJ f 99.3333333333 22.1850180487 143.0355479216 55.631118745
CC018/UncJ m 81.0 17.1844410876 114.8515898586 47.1484101414
CC019/TauUncJ f 90.8 17.1844410876 124.6515898586 56.9484101414
CC019/TauUncJ m 27.3333333333 22.1850180487 71.0355479216 -16.368881255
CC023/GeniUncJ f 22.3333333333 22.1850180487 66.0355479216 -21.368881255
CC023/GeniUncJ m 25.6666666667 22.1850180487 69.368881255 -18.0355479216
CC024/GeniUncJ f 24.0 27.1709870769 77.5240631855 -29.5240631855
CC024/GeniUncJ m 13.0 27.1709870769 66.5240631855 -40.5240631855
CC026/GeniUncJ f 20.2 17.1844410876 54.0515898586 -13.6515898586
CC026/GeniUncJ m 20.3333333333 22.1850180487 64.0355479216 -23.368881255
CC027/GeniUncJ f 64.25 19.2127892136 102.0972280351 26.4027719649
CC027/GeniUncJ m 24.5 19.2127892136 62.3472280351 -13.3472280351
CC028/GeniUncJ f 69.0 19.2127892136 106.8472280351 31.1527719649
CC028/GeniUncJ m 38.6 17.1844410876 72.4515898586 4.7484101414
CC030/GeniUncJ f 52.5 27.1709870769 106.0240631855 -1.0240631855
CC030/GeniUncJ m 65.5 27.1709870769 119.0240631855 11.9759368145
CC032/GeniUncJ f 34.6666666667 22.1850180487 78.368881255 -9.0355479216
CC032/GeniUncJ m 44.25 19.2127892136 82.0972280351 6.4027719649
CC035/UncJ f 18.6666666667 22.1850180487 62.368881255 -25.0355479216
CC035/UncJ m 55.0 27.1709870769 108.5240631855 1.4759368145
CC036/UncJ f 122.0 22.1850180487 165.7022145883 78.2977854117
CC036/UncJ m 65.0 27.1709870769 118.5240631855 11.4759368145
CC040/TauUncJ f 22.5 27.1709870769 76.0240631855 -31.0240631855
CC040/TauUncJ m 57.0 27.1709870769 110.5240631855 3.4759368145
CC041/TauUncJ f 12.0 27.1709870769 65.5240631855 -41.5240631855
CC041/TauUncJ m 4.4166666667 11.0925090244 26.2677739608 -17.4344406275
CC044/UncJ f 2.0 27.1709870769 55.5240631855 -51.5240631855
CC044/UncJ m 38.0 27.1709870769 91.5240631855 -15.5240631855
CC051/TauUncJ f 32.5 27.1709870769 86.0240631855 -21.0240631855
CC051/TauUncJ m 35.6666666667 22.1850180487 79.368881255 -8.0355479216
CC057/UncJ f 93.5 27.1709870769 147.0240631855 39.9759368145
CC057/UncJ m 22.0 27.1709870769 75.5240631855 -31.5240631855
CC059/TauUncJ f 153.0 19.2127892136 190.8472280351 115.1527719649
CC059/TauUncJ m 48.0 22.1850180487 91.7022145883 4.2977854117
CC061/GeniUncJ f 88.0 27.1709870769 141.5240631855 34.4759368145
CC061/GeniUncJ m 78.5 27.1709870769 132.0240631855 24.9759368145
CC068/TauUncJ f 0.0 27.1709870769 53.5240631855 -53.5240631855
CC068/TauUncJ m 1.0 27.1709870769 54.5240631855 -52.5240631855
CC078/TauUncJ f 71.0 27.1709870769 124.5240631855 17.4759368145
CC078/TauUncJ m 64.3333333333 22.1850180487 108.0355479216 20.631118745
CC079/TauUncJ f 97.5 27.1709870769 151.0240631855 43.9759368145
CC079/TauUncJ m 69.0 27.1709870769 122.5240631855 15.4759368145
NOD/ShiLtJ f 28.1818181818 11.5857478178 51.0045554086 5.359080955
NOD/ShiLtJ m 32.6666666667 15.687176703 63.5687989549 1.7645343784
NZO/HlLtJ f 32.6 12.1512348239 56.5366887429 8.6633112571
NZO/HlLtJ m 31.3 12.1512348239 55.2366887429 7.3633112571
PWK/PhJ f 58.8571428571 14.5235035003 87.4669580554 30.2473276588
PWK/PhJ m 57.5 15.687176703 88.4021322883 26.5978677117
WSB/EiJ f 56.0 22.1850180487 99.7022145883 12.2977854117
WSB/EiJ m 48.2 17.1844410876 82.0515898586 14.3484101414


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
A/J both 43.3571428571 9.6823356669 62.4303529893 24.2839327249
C57BL/6J both 57.1923076923 7.6912711656 72.3433245721 42.0412908126
CC001/UncJ both 35.2083333333 14.6740101471 64.1146312192 6.3020354475
CC002/UncJ both 109.0833333333 17.5387967415 143.6329675564 74.5336991102
CC003/UncJ both 18.375 16.6387635365 51.1516609412 -14.4016609412
CC004/TauUncJ both 117.2514619883 7.7744804991 132.5663927374 101.9365312392
CC005/TauUncJ both 14.75 16.6387635365 47.5266609412 -18.0266609412
CC006/TauUncJ both 54.75 19.2127892136 92.5972280351 16.9027719649
CC007/UncJ both 46.5 17.5387967415 81.0496342231 11.9503657769
CC008/GeniUncJ both 23.25 19.2127892136 61.0972280351 -14.5972280351
CC009/UncJ both 36.1666666667 15.687176703 67.0687989549 5.2645343784
CC011/UncJ both 55.6666666667 15.687176703 86.5687989549 24.7645343784
CC013/GeniUncJ both 63.5 15.687176703 94.4021322883 32.5978677117
CC016/GeniUncJ both 32.0 19.2127892136 69.8472280351 -5.8472280351
CC017/UncJ both 10.75 14.6740101471 39.6562978859 -18.1562978859
CC018/UncJ both 90.1666666667 14.0310373932 117.8063740452 62.5269592882
CC019/TauUncJ both 59.0666666667 14.0310373932 86.7063740452 31.4269592882
CC023/GeniUncJ both 24.0 15.687176703 54.9021322883 -6.9021322883
CC024/GeniUncJ both 18.5 19.2127892136 56.3472280351 -19.3472280351
CC026/GeniUncJ both 20.2666666667 14.0310373932 47.9063740452 -7.3730407118
CC027/GeniUncJ both 44.375 13.5854935384 71.1370315927 17.6129684073
CC028/GeniUncJ both 53.8 12.8883308157 79.1886923939 28.4113076061
CC030/GeniUncJ both 59.0 19.2127892136 96.8472280351 21.1527719649
CC032/GeniUncJ both 39.4583333333 14.6740101471 68.3646312192 10.5520354475
CC035/UncJ both 36.8333333333 17.5387967415 71.3829675564 2.2836991102
CC036/UncJ both 93.5 17.5387967415 128.0496342231 58.9503657769
CC040/TauUncJ both 39.75 19.2127892136 77.5972280351 1.9027719649
CC041/TauUncJ both 8.2083333333 14.6740101471 37.1146312192 -20.6979645525
CC044/UncJ both 20.0 19.2127892136 57.8472280351 -17.8472280351
CC051/TauUncJ both 34.0833333333 17.5387967415 68.6329675564 -0.4663008898
CC057/UncJ both 57.75 19.2127892136 95.5972280351 19.9027719649
CC059/TauUncJ both 100.5 14.6740101471 129.4062978859 71.5937021141
CC061/GeniUncJ both 83.25 19.2127892136 121.0972280351 45.4027719649
CC068/TauUncJ both 0.5 19.2127892136 38.3472280351 -37.3472280351
CC078/TauUncJ both 67.6666666667 17.5387967415 102.2163008898 33.1170324436
CC079/TauUncJ both 83.25 19.2127892136 121.0972280351 45.4027719649
NOD/ShiLtJ both 30.4242424242 9.750859775 49.632438035 11.2160468135
NZO/HlLtJ both 31.95 8.5922205438 48.8757949293 15.0242050707
PWK/PhJ both 58.1785714286 10.6890091547 79.2348252837 37.1223175735
WSB/EiJ both 52.1 14.0310373932 79.7397073785 24.4602926215




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA