Project measure / variable:   CSNA03   reinstatement_inactive_cc_s2

ID, description, units MPD:110421   reinstatement_inactive_cc_s2   reinstatement, inactive lever presses (intravenous self administration), CC   [n]  session 2  
cocaine study
Data set, strains CSNA03   CC w/par   54 strains     sex: both     age:
Procedure operant conditioning chamber
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  STRAIN COMPARISON PLOT
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CSNA03 - reinstatement, inactive lever presses (intravenous self administration), CC session 2



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested52 strains51 strains
Mean of the strain means59.93   n 87.18   n
Median of the strain means30.791   n 24.8   n
SD of the strain means± 74.28 ± 200.0
Coefficient of variation (CV)1.2395 2.2939
Min–max range of strain means0.0   –   322.0   n 0.0   –   1334.0   n
Mean sample size per strain3.2   mice 3.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 34847.1978 34847.1978 1.4488 0.2299
strain 39 3755551.689 96296.1972 4.0037 < 0.0001
sex:strain 39 2801385.5764 71830.3994 2.9865 < 0.0001
Residuals 240 5772427.5087 24051.7813


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
A/J f 7.3333 13.096   9 4.3653 1.7858 -0.71
A/J m 50.43 92.84   7 35.092 1.8411 -0.18
C57BL/6J f 31.583 32.759   12 9.4568 1.0372 1.0, 105.0 -0.38
C57BL/6J m 11.615 8.94   13 2.4795 0.7697 -0.38
CAST/EiJ f 30.0 0.0   1   0.0 0.0 30.0, 30.0 -0.4
CAST/EiJ m 63.0 86.27   2   61.0 1.3693 2.0, 124.0 -0.12
CC001/UncJ f 58.0 87.54   3 50.54 1.5093 4.0, 159.0 -0.03
CC001/UncJ m 129.8 145.8   4 72.88 1.1235 10.0, 306.0 0.21
CC002/UncJ f 193.3 233.8   3 135.0 1.2092 15.0, 458.0 1.8
CC002/UncJ m 60.5 84.15   2   59.5 1.3908 1.0, 120.0 -0.13
CC003/UncJ f 54.5 57.28   2   40.5 1.0509 14.0, 95.0 -0.07
CC003/UncJ m 5.0 2.3094   4 1.1547 0.4619 3.0, 7.0 -0.41
CC004/TauUncJ f 138.6 152.8   9 50.94 1.103 1.06
CC004/TauUncJ m 129.1 151.5   19 34.765 1.1737 9.0, 653.0 0.21
CC005/TauUncJ f 9.5 9.9833   4 4.9917 1.0509 2.0, 24.0 -0.68
CC005/TauUncJ m 2.0 1.4142   2   1.0 0.7071 1.0, 3.0 -0.43
CC006/TauUncJ f 81.5 67.18   2   47.5 0.8242 34.0, 129.0 0.29
CC006/TauUncJ m 31.5 44.548   2   31.5 1.4142 -0.28
CC007/UncJ f 95.0 134.4   2   95.0 1.4142 0.47
CC007/UncJ m 10.333 11.372   3 6.5659 1.1006 1.0, 23.0 -0.38
CC008/GeniUncJ f 4.0 2.8284   2   2.0 0.7071 2.0, 6.0 -0.75
CC008/GeniUncJ m 20.0 11.314   2   8.0 0.5657 12.0, 28.0 -0.34
CC009/UncJ f 31.667 36.474   3 21.058 1.1518 1.0, 72.0 -0.38
CC009/UncJ m 1.6667 2.8868   3 1.6667 1.7321 -0.43
CC011/UncJ f 80.67 66.89   3 38.619 0.8292 23.0, 154.0 0.28
CC011/UncJ m 139.0 127.7   3 73.75 0.919 55.0, 286.0 0.26
CC012/GeniUncJ f 322.0 0.0   1   0.0 0.0 322.0, 322.0 3.53
CC012/GeniUncJ m 65.0 60.56   3 34.962 0.9316 6.0, 127.0 -0.11
CC013/GeniUncJ f 229.3 182.4   3 105.3 0.7955 30.0, 388.0 2.28
CC013/GeniUncJ m 149.3 198.3   3 114.5 1.3278 8.0, 376.0 0.31
CC015/UncJ f 4.5 6.364   2   4.5 1.4142 -0.75
CC015/UncJ m 62.0 0.0   1   0.0 0.0 62.0, 62.0 -0.13
CC016/GeniUncJ f 9.0 8.4853   2   6.0 0.9428 3.0, 15.0 -0.69
CC016/GeniUncJ m 0.5 0.70711   2   0.5 1.4142 -0.43
CC017/UncJ f 7.0 5.0   3 2.8868 0.7143 2.0, 12.0 -0.71
CC017/UncJ m 0.75 0.95743   4 0.47871 1.2766 -0.43
CC018/UncJ f 76.67 72.04   3 41.591 0.9396 6.0, 150.0 0.23
CC018/UncJ m 76.4 16.532   5 7.3932 0.2164 49.0, 91.0 -0.05
CC019/TauUncJ f 198.2 254.5   5 113.8 1.2842 9.0, 603.0 1.86
CC019/TauUncJ m 156.7 270.5   3 156.2 1.7265 0.35
CC020/GeniUncJ f 15.0 0.0   1   0.0 0.0 15.0, 15.0 -0.6
CC023/GeniUncJ f 12.0 17.349   3 10.017 1.4458 1.0, 32.0 -0.65
CC023/GeniUncJ m 21.667 17.214   3 9.9387 0.7945 8.0, 41.0 -0.33
CC024/GeniUncJ f 0.5 0.70711   2   0.5 1.4142 -0.8
CC024/GeniUncJ m 55.0 45.255   2   32.0 0.8228 23.0, 87.0 -0.16
CC025/GeniUncJ f 119.5 160.5   2   113.5 1.3432 6.0, 233.0 0.8
CC025/GeniUncJ m 259.0 0.0   1   0.0 0.0 259.0, 259.0 0.86
CC026/GeniUncJ f 10.2 14.601   5 6.5299 1.4315 -0.67
CC026/GeniUncJ m 7.0 8.1854   3 4.7258 1.1693 -0.4
CC027/GeniUncJ f 214.2 258.8   4 129.4 1.2079 3.0, 537.0 2.08
CC027/GeniUncJ m 19.0 18.655   4 9.3274 0.9818 2.0, 38.0 -0.34
CC028/GeniUncJ f 74.25 69.41   4 34.707 0.9349 15.0, 151.0 0.19
CC028/GeniUncJ m 65.8 93.96   5 42.018 1.4279 8.0, 233.0 -0.11
CC029/UncJ f 4.0 0.0   1   0.0 0.0 4.0, 4.0 -0.75
CC029/UncJ m 24.0 0.0   1   0.0 0.0 24.0, 24.0 -0.32
CC030/GeniUncJ f 27.5 37.477   2   26.5 1.3628 1.0, 54.0 -0.44
CC030/GeniUncJ m 235.5 282.1   2   199.5 1.198 36.0, 435.0 0.74
CC032/GeniUncJ f 52.33 32.716   3 18.889 0.6251 22.0, 87.0 -0.1
CC032/GeniUncJ m 25.5 16.543   4 8.2714 0.6487 3.0, 42.0 -0.31
CC033/GeniUncJ f 0.0 0.0   1   0.0 None -0.81
CC033/GeniUncJ m 14.5 9.1924   2   6.5 0.634 8.0, 21.0 -0.36
CC035/UncJ f 26.333 22.279   3 12.863 0.846 12.0, 52.0 -0.45
CC035/UncJ m 67.5 30.406   2   21.5 0.4505 46.0, 89.0 -0.1
CC036/UncJ f 173.7 185.9   3 107.3 1.0702 57.0, 388.0 1.53
CC036/UncJ m 363.0 72.12   2   51.0 0.1987 312.0, 414.0 1.38
CC037/TauUncJ f 8.0 0.0   1   0.0 0.0 8.0, 8.0 -0.7
CC037/TauUncJ m 0.0 0.0   1   0.0 None -0.44
CC040/TauUncJ f 6.5 2.1213   2   1.5 0.3264 5.0, 8.0 -0.72
CC040/TauUncJ m 14.5 0.70711   2   0.5 0.0488 14.0, 15.0 -0.36
CC041/TauUncJ f 0.0 0.0   2   0.0 None -0.81
CC041/TauUncJ m 2.9167 6.2734   12 1.811 2.1509 -0.42
CC043/GeniUncJ m 1.0 0.0   1   0.0 0.0 1.0, 1.0 -0.43
CC044/UncJ f 3.5 4.9497   2   3.5 1.4142 -0.76
CC044/UncJ m 57.0 72.12   2   51.0 1.2653 6.0, 108.0 -0.15
CC051/TauUncJ f 80.5 102.5   2   72.5 1.2737 8.0, 153.0 0.28
CC051/TauUncJ m 17.333 12.055   3 6.9602 0.6955 6.0, 30.0 -0.35
CC057/UncJ f 44.0 29.698   2   21.0 0.675 23.0, 65.0 -0.21
CC057/UncJ m 2.0 1.4142   2   1.0 0.7071 1.0, 3.0 -0.43
CC059/TauUncJ f 120.2 142.8   4 71.41 1.1877 9.0, 325.0 0.81
CC059/TauUncJ m 1334.0 1207.0   3 696.8 0.9047 3.0, 2357.0 6.23
CC060/UncJ m 57.0 0.0   1   0.0 0.0 57.0, 57.0 -0.15
CC061/GeniUncJ f 71.5 95.46   2   67.5 1.3351 4.0, 139.0 0.16
CC061/GeniUncJ m 33.5 20.506   2   14.5 0.6121 19.0, 48.0 -0.27
CC068/TauUncJ f 0.5 0.70711   2   0.5 1.4142 -0.8
CC068/TauUncJ m 0.0 0.0   2   0.0 None -0.44
CC074/UncJ f 1.0 0.0   1   0.0 0.0 1.0, 1.0 -0.79
CC074/UncJ m 18.0 0.0   1   0.0 0.0 18.0, 18.0 -0.35
CC075/UncJ f 2.0 0.0   1   0.0 0.0 2.0, 2.0 -0.78
CC078/TauUncJ f 209.5 245.4   2   173.5 1.1712 36.0, 383.0 2.01
CC078/TauUncJ m 448.7 612.6   3 353.7 1.3654 62.0, 1155.0 1.81
CC079/TauUncJ f 32.0 21.213   2   15.0 0.6629 17.0, 47.0 -0.38
CC079/TauUncJ m 11.0 2.8284   2   2.0 0.2571 9.0, 13.0 -0.38
CC080/TauUncJ f 0.5 0.70711   2   0.5 1.4142 -0.8
CC084/TauJ f 45.5 0.70711   2   0.5 0.0155 45.0, 46.0 -0.19
CC084/TauJ m 24.0 0.0   1   0.0 0.0 24.0, 24.0 -0.32
NOD/ShiLtJ f 26.455 42.113   11 12.697 1.5919 -0.45
NOD/ShiLtJ m 14.667 12.061   6 4.9239 0.8223 4.0, 31.0 -0.36
NZO/HlLtJ f 9.5 9.2646   10 2.9297 0.9752 -0.68
NZO/HlLtJ m 16.1 21.687   10 6.858 1.347 1.0, 73.0 -0.36
PWK/PhJ f 26.286 17.124   7 6.4723 0.6515 11.0, 56.0 -0.45
PWK/PhJ m 47.667 54.23   6 22.14 1.1377 5.0, 146.0 -0.2
WSB/EiJ f 37.0 40.927   3 23.629 1.1061 2.0, 82.0 -0.31
WSB/EiJ m 24.8 32.322   5 14.455 1.3033 3.0, 82.0 -0.31


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J f 7.3333333333 51.6954557281 109.1680893164 -94.5014226497
A/J m 50.4285714286 58.6171370438 165.8983310661 -65.0411882089
C57BL/6J f 31.5833333333 44.7695779208 119.7748190029 -56.6081523362
C57BL/6J m 11.6153846154 43.0132191545 96.3470233049 -73.1162540741
CC001/UncJ f 58.0 89.5391558416 234.382971339 -118.382971339
CC001/UncJ m 129.75 77.5431835922 282.5021339746 -23.0021339746
CC002/UncJ f 193.3333333333 89.5391558416 369.7163046724 16.9503619943
CC002/UncJ m 60.5 109.6626219057 276.5241395483 -155.5241395483
CC003/UncJ f 54.5 109.6626219057 270.5241395483 -161.5241395483
CC003/UncJ m 5.0 77.5431835922 157.7521339746 -147.7521339746
CC004/TauUncJ f 138.5555555556 51.6954557281 240.3903115386 36.7207995725
CC004/TauUncJ m 129.1052631579 35.5792527409 199.19274899 59.0177773257
CC005/TauUncJ f 9.5 77.5431835922 162.2521339746 -143.2521339746
CC005/TauUncJ m 2.0 109.6626219057 218.0241395483 -214.0241395483
CC006/TauUncJ f 81.5 109.6626219057 297.5241395483 -134.5241395483
CC006/TauUncJ m 31.5 109.6626219057 247.5241395483 -184.5241395483
CC007/UncJ f 95.0 109.6626219057 311.0241395483 -121.0241395483
CC007/UncJ m 10.3333333333 89.5391558416 186.7163046724 -166.0496380057
CC008/GeniUncJ f 4.0 109.6626219057 220.0241395483 -212.0241395483
CC008/GeniUncJ m 20.0 109.6626219057 236.0241395483 -196.0241395483
CC009/UncJ f 31.6666666667 89.5391558416 208.0496380057 -144.7163046724
CC009/UncJ m 1.6666666667 89.5391558416 178.0496380057 -174.7163046724
CC011/UncJ f 80.6666666667 89.5391558416 257.0496380057 -95.7163046724
CC011/UncJ m 139.0 89.5391558416 315.382971339 -37.382971339
CC013/GeniUncJ f 229.3333333333 89.5391558416 405.7163046724 52.9503619943
CC013/GeniUncJ m 149.3333333333 89.5391558416 325.7163046724 -27.0496380057
CC016/GeniUncJ f 9.0 109.6626219057 225.0241395483 -207.0241395483
CC016/GeniUncJ m 0.5 109.6626219057 216.5241395483 -215.5241395483
CC017/UncJ f 7.0 89.5391558416 183.382971339 -169.382971339
CC017/UncJ m 0.75 77.5431835922 153.5021339746 -152.0021339746
CC018/UncJ f 76.6666666667 89.5391558416 253.0496380057 -99.7163046724
CC018/UncJ m 76.4 69.3567318816 213.0256621101 -60.2256621101
CC019/TauUncJ f 198.2 69.3567318816 334.8256621101 61.5743378899
CC019/TauUncJ m 156.6666666667 89.5391558416 333.0496380057 -19.7163046724
CC023/GeniUncJ f 12.0 89.5391558416 188.382971339 -164.382971339
CC023/GeniUncJ m 21.6666666667 89.5391558416 198.0496380057 -154.7163046724
CC024/GeniUncJ f 0.5 109.6626219057 216.5241395483 -215.5241395483
CC024/GeniUncJ m 55.0 109.6626219057 271.0241395483 -161.0241395483
CC026/GeniUncJ f 10.2 69.3567318816 146.8256621101 -126.4256621101
CC026/GeniUncJ m 7.0 89.5391558416 183.382971339 -169.382971339
CC027/GeniUncJ f 214.25 77.5431835922 367.0021339746 61.4978660254
CC027/GeniUncJ m 19.0 77.5431835922 171.7521339746 -133.7521339746
CC028/GeniUncJ f 74.25 77.5431835922 227.0021339746 -78.5021339746
CC028/GeniUncJ m 65.8 69.3567318816 202.4256621101 -70.8256621101
CC030/GeniUncJ f 27.5 109.6626219057 243.5241395483 -188.5241395483
CC030/GeniUncJ m 235.5 109.6626219057 451.5241395483 19.4758604517
CC032/GeniUncJ f 52.3333333333 89.5391558416 228.7163046724 -124.0496380057
CC032/GeniUncJ m 25.5 77.5431835922 178.2521339746 -127.2521339746
CC035/UncJ f 26.3333333333 89.5391558416 202.7163046724 -150.0496380057
CC035/UncJ m 67.5 109.6626219057 283.5241395483 -148.5241395483
CC036/UncJ f 173.6666666667 89.5391558416 350.0496380057 -2.7163046724
CC036/UncJ m 363.0 109.6626219057 579.0241395483 146.9758604517
CC040/TauUncJ f 6.5 109.6626219057 222.5241395483 -209.5241395483
CC040/TauUncJ m 14.5 109.6626219057 230.5241395483 -201.5241395483
CC041/TauUncJ f 0.0 109.6626219057 216.0241395483 -216.0241395483
CC041/TauUncJ m 2.9166666667 44.7695779208 91.1081523362 -85.2748190029
CC044/UncJ f 3.5 109.6626219057 219.5241395483 -212.5241395483
CC044/UncJ m 57.0 109.6626219057 273.0241395483 -159.0241395483
CC051/TauUncJ f 80.5 109.6626219057 296.5241395483 -135.5241395483
CC051/TauUncJ m 17.3333333333 89.5391558416 193.7163046724 -159.0496380057
CC057/UncJ f 44.0 109.6626219057 260.0241395483 -172.0241395483
CC057/UncJ m 2.0 109.6626219057 218.0241395483 -214.0241395483
CC059/TauUncJ f 120.25 77.5431835922 273.0021339746 -32.5021339746
CC059/TauUncJ m 1334.0 89.5391558416 1510.382971339 1157.617028661
CC061/GeniUncJ f 71.5 109.6626219057 287.5241395483 -144.5241395483
CC061/GeniUncJ m 33.5 109.6626219057 249.5241395483 -182.5241395483
CC068/TauUncJ f 0.5 109.6626219057 216.5241395483 -215.5241395483
CC068/TauUncJ m 0.0 109.6626219057 216.0241395483 -216.0241395483
CC078/TauUncJ f 209.5 109.6626219057 425.5241395483 -6.5241395483
CC078/TauUncJ m 448.6666666667 89.5391558416 625.0496380057 272.2836953276
CC079/TauUncJ f 32.0 109.6626219057 248.0241395483 -184.0241395483
CC079/TauUncJ m 11.0 109.6626219057 227.0241395483 -205.0241395483
NOD/ShiLtJ f 26.4545454545 46.7602990954 118.5675480581 -65.6584571491
NOD/ShiLtJ m 14.6666666667 63.3137442773 139.3882617863 -110.054928453
NZO/HlLtJ f 9.5 49.0426154344 106.1089321622 -87.1089321622
NZO/HlLtJ m 16.1 49.0426154344 112.7089321622 -80.5089321622
PWK/PhJ f 26.2857142857 58.6171370438 141.7554739232 -89.1840453518
PWK/PhJ m 47.6666666667 63.3137442773 172.3882617863 -77.054928453
WSB/EiJ f 37.0 89.5391558416 213.382971339 -139.382971339
WSB/EiJ m 24.8 69.3567318816 161.4256621101 -111.8256621101


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
A/J both 28.880952381 39.0780913625 105.8607921393 -48.0988873774
C57BL/6J both 21.5993589744 31.042117072 82.7491519822 -39.5504340335
CC001/UncJ both 93.875 59.2245847399 210.5413694174 -22.7913694174
CC002/UncJ both 126.9166666667 70.786918057 266.3596491416 -12.5263158082
CC003/UncJ both 29.75 67.1543668812 162.0372285043 -102.5372285043
CC004/TauUncJ both 133.8304093567 31.3779515287 195.6417618666 72.0190568468
CC005/TauUncJ both 5.75 67.1543668812 138.0372285043 -126.5372285043
CC006/TauUncJ both 56.5 77.5431835922 209.2521339746 -96.2521339746
CC007/UncJ both 52.6666666667 70.786918057 192.1096491416 -86.7763158082
CC008/GeniUncJ both 12.0 77.5431835922 164.7521339746 -140.7521339746
CC009/UncJ both 16.6666666667 63.3137442773 141.3882617863 -108.054928453
CC011/UncJ both 109.8333333333 63.3137442773 234.554928453 -14.8882617863
CC013/GeniUncJ both 189.3333333333 63.3137442773 314.054928453 64.6117382137
CC016/GeniUncJ both 4.75 77.5431835922 157.5021339746 -148.0021339746
CC017/UncJ both 3.875 59.2245847399 120.5413694174 -112.7913694174
CC018/UncJ both 76.5333333333 56.6295344456 188.0877193132 -35.0210526466
CC019/TauUncJ both 177.4333333333 56.6295344456 288.9877193132 65.8789473534
CC023/GeniUncJ both 16.8333333333 63.3137442773 141.554928453 -107.8882617863
CC024/GeniUncJ both 27.75 77.5431835922 180.5021339746 -125.0021339746
CC026/GeniUncJ both 8.6 56.6295344456 120.1543859799 -102.9543859799
CC027/GeniUncJ both 116.625 54.8313109528 224.6370697741 8.6129302259
CC028/GeniUncJ both 70.025 52.0175489112 172.4942465826 -32.4442465826
CC030/GeniUncJ both 131.5 77.5431835922 284.2521339746 -21.2521339746
CC032/GeniUncJ both 38.9166666667 59.2245847399 155.5830360841 -77.7497027508
CC035/UncJ both 46.9166666667 70.786918057 186.3596491416 -92.5263158082
CC036/UncJ both 268.3333333333 70.786918057 407.7763158082 128.8903508584
CC040/TauUncJ both 10.5 77.5431835922 163.2521339746 -142.2521339746
CC041/TauUncJ both 1.4583333333 59.2245847399 118.1247027508 -115.2080360841
CC044/UncJ both 30.25 77.5431835922 183.0021339746 -122.5021339746
CC051/TauUncJ both 48.9166666667 70.786918057 188.3596491416 -90.5263158082
CC057/UncJ both 23.0 77.5431835922 175.7521339746 -129.7521339746
CC059/TauUncJ both 727.125 59.2245847399 843.7913694174 610.4586305826
CC061/GeniUncJ both 52.5 77.5431835922 205.2521339746 -100.2521339746
CC068/TauUncJ both 0.25 77.5431835922 153.0021339746 -152.5021339746
CC078/TauUncJ both 329.0833333333 70.786918057 468.5263158082 189.6403508584
CC079/TauUncJ both 21.5 77.5431835922 174.2521339746 -131.2521339746
NOD/ShiLtJ both 20.5606060606 39.3546559695 98.0852497841 -56.9640376629
NZO/HlLtJ both 12.8 34.6783659408 81.1128310551 -55.5128310551
PWK/PhJ both 36.9761904762 43.1410447533 121.9596325104 -48.007251558
WSB/EiJ both 30.9 56.6295344456 142.4543859799 -80.6543859799




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA