Project measure / variable:   CSNA03   reinstatement_inactive_cc_s1

ID, description, units MPD:110420   reinstatement_inactive_cc_s1   reinstatement, inactive lever presses (intravenous self administration), CC   [n]  session 1  
cocaine study
Data set, strains CSNA03   CC w/par   54 strains     sex: both     age:
Procedure operant conditioning chamber
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  STRAIN COMPARISON PLOT
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CSNA03 - reinstatement, inactive lever presses (intravenous self administration), CC session 1



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested52 strains51 strains
Mean of the strain means63.87   n 78.54   n
Median of the strain means31.0   n 20.0   n
SD of the strain means± 75.61 ± 202.0
Coefficient of variation (CV)1.1838 2.5719
Min–max range of strain means0.0   –   326.0   n 0.0   –   1341.0   n
Mean sample size per strain3.2   mice 3.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 13006.9353 13006.9353 0.5467 0.4604
strain 39 3759465.1787 96396.543 4.0516 < 0.0001
sex:strain 39 2973295.7336 76238.3521 3.2043 < 0.0001
Residuals 240 5710188.9524 23792.454


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
A/J f 10.222 8.0743   9 2.6914 0.7899 -0.71
A/J m 129.6 307.0   7 116.0 2.3691 0.25
C57BL/6J f 42.5 46.615   12 13.457 1.0968 -0.28
C57BL/6J m 10.846 9.856   13 2.7336 0.9087 -0.34
CAST/EiJ f 89.0 0.0   1   0.0 0.0 89.0, 89.0 0.33
CAST/EiJ m 32.0 39.598   2   28.0 1.2374 4.0, 60.0 -0.23
CC001/UncJ f 28.0 28.618   3 16.523 1.0221 10.0, 61.0 -0.47
CC001/UncJ m 117.0 83.45   4 41.727 0.7133 31.0, 216.0 0.19
CC002/UncJ f 213.7 116.1   3 67.04 0.5435 86.0, 313.0 1.98
CC002/UncJ m 20.0 21.213   2   15.0 1.0607 5.0, 35.0 -0.29
CC003/UncJ f 168.0 222.0   2   157.0 1.3216 11.0, 325.0 1.38
CC003/UncJ m 5.25 3.9476   4 1.9738 0.7519 2.0, 11.0 -0.36
CC004/TauUncJ f 108.2 106.4   9 35.483 0.9836 0.59
CC004/TauUncJ m 103.1 99.98   19 22.937 0.9697 3.0, 349.0 0.12
CC005/TauUncJ f 18.75 28.289   4 14.144 1.5087 1.0, 61.0 -0.6
CC005/TauUncJ m 2.5 0.70711   2   0.5 0.2828 2.0, 3.0 -0.38
CC006/TauUncJ f 67.5 58.69   2   41.5 0.8695 26.0, 109.0 0.05
CC006/TauUncJ m 40.5 57.28   2   40.5 1.4142 -0.19
CC007/UncJ f 3.5 4.9497   2   3.5 1.4142 -0.8
CC007/UncJ m 6.0 6.0   3 3.4641 1.0 -0.36
CC008/GeniUncJ f 5.5 6.364   2   4.5 1.1571 1.0, 10.0 -0.77
CC008/GeniUncJ m 19.5 26.163   2   18.5 1.3417 1.0, 38.0 -0.29
CC009/UncJ f 42.333 42.099   3 24.306 0.9945 2.0, 86.0 -0.28
CC009/UncJ m 0.66667 0.57735   3 0.33333 0.866 -0.39
CC011/UncJ f 73.67 63.81   3 36.844 0.8663 22.0, 145.0 0.13
CC011/UncJ m 80.33 46.199   3 26.673 0.5751 43.0, 132.0 0.01
CC012/GeniUncJ f 197.0 0.0   1   0.0 0.0 197.0, 197.0 1.76
CC012/GeniUncJ m 61.0 19.975   3 11.533 0.3275 39.0, 78.0 -0.09
CC013/GeniUncJ f 259.0 217.9   3 125.8 0.8414 10.0, 415.0 2.58
CC013/GeniUncJ m 110.3 145.5   3 83.98 1.3183 9.0, 277.0 0.16
CC015/UncJ f 6.0 8.4853   2   6.0 1.4142 -0.77
CC015/UncJ m 68.0 0.0   1   0.0 0.0 68.0, 68.0 -0.05
CC016/GeniUncJ f 26.5 36.062   2   25.5 1.3608 1.0, 52.0 -0.49
CC016/GeniUncJ m 1.5 2.1213   2   1.5 1.4142 -0.38
CC017/UncJ f 14.667 20.306   3 11.724 1.3845 1.0, 38.0 -0.65
CC017/UncJ m 0.75 0.95743   4 0.47871 1.2766 -0.39
CC018/UncJ f 121.0 108.1   3 62.39 0.893 11.0, 227.0 0.76
CC018/UncJ m 68.4 28.615   5 12.797 0.4183 36.0, 101.0 -0.05
CC019/TauUncJ f 167.2 237.1   5 106.0 1.4178 9.0, 572.0 1.37
CC019/TauUncJ m 67.0 88.5   3 51.1 1.321 3.0, 168.0 -0.06
CC020/GeniUncJ f 17.0 0.0   1   0.0 0.0 17.0, 17.0 -0.62
CC023/GeniUncJ f 22.333 29.16   3 16.836 1.3057 5.0, 56.0 -0.55
CC023/GeniUncJ m 20.0 20.518   3 11.846 1.0259 -0.29
CC024/GeniUncJ f 20.5 28.991   2   20.5 1.4142 -0.57
CC024/GeniUncJ m 51.0 12.728   2   9.0 0.2496 42.0, 60.0 -0.14
CC025/GeniUncJ f 169.0 229.1   2   162.0 1.3556 7.0, 331.0 1.39
CC025/GeniUncJ m 140.0 0.0   1   0.0 0.0 140.0, 140.0 0.3
CC026/GeniUncJ f 12.0 8.124   5 3.6332 0.677 4.0, 24.0 -0.69
CC026/GeniUncJ m 3.0 1.7321   3 1.0 0.5774 2.0, 5.0 -0.37
CC027/GeniUncJ f 145.2 214.6   4 107.3 1.4774 4.0, 465.0 1.08
CC027/GeniUncJ m 16.0 7.874   4 3.937 0.4921 8.0, 25.0 -0.31
CC028/GeniUncJ f 133.0 128.2   4 64.09 0.9638 16.0, 263.0 0.91
CC028/GeniUncJ m 58.4 84.46   5 37.774 1.4463 9.0, 209.0 -0.1
CC029/UncJ f 2.0 0.0   1   0.0 0.0 2.0, 2.0 -0.82
CC029/UncJ m 14.0 0.0   1   0.0 0.0 14.0, 14.0 -0.32
CC030/GeniUncJ f 94.5 48.79   2   34.5 0.5163 60.0, 129.0 0.41
CC030/GeniUncJ m 134.5 173.2   2   122.5 1.288 12.0, 257.0 0.28
CC032/GeniUncJ f 58.0 35.0   3 20.207 0.6034 23.0, 93.0 -0.08
CC032/GeniUncJ m 16.5 14.387   4 7.1937 0.872 8.0, 38.0 -0.31
CC033/GeniUncJ f 1.0 0.0   1   0.0 0.0 1.0, 1.0 -0.83
CC033/GeniUncJ m 5.5 2.1213   2   1.5 0.3857 4.0, 7.0 -0.36
CC035/UncJ f 6.3333 8.5049   3 4.9103 1.3429 -0.76
CC035/UncJ m 50.5 40.305   2   28.5 0.7981 22.0, 79.0 -0.14
CC036/UncJ f 165.7 92.4   3 53.35 0.5577 59.0, 221.0 1.35
CC036/UncJ m 439.5 78.49   2   55.5 0.1786 384.0, 495.0 1.79
CC037/TauUncJ f 7.0 0.0   1   0.0 0.0 7.0, 7.0 -0.75
CC037/TauUncJ m 0.0 0.0   1   0.0 None -0.39
CC040/TauUncJ f 2.5 2.1213   2   1.5 0.8485 1.0, 4.0 -0.81
CC040/TauUncJ m 2.5 0.70711   2   0.5 0.2828 2.0, 3.0 -0.38
CC041/TauUncJ f 0.0 0.0   2   0.0 None -0.84
CC041/TauUncJ m 1.0833 1.9287   12 0.55675 1.7803 -0.38
CC043/GeniUncJ m 9.0 0.0   1   0.0 0.0 9.0, 9.0 -0.34
CC044/UncJ f 2.0 1.4142   2   1.0 0.7071 1.0, 3.0 -0.82
CC044/UncJ m 38.0 53.74   2   38.0 1.4142 -0.2
CC051/TauUncJ f 15.0 11.314   2   8.0 0.7542 7.0, 23.0 -0.65
CC051/TauUncJ m 19.667 8.3267   3 4.8074 0.4234 13.0, 29.0 -0.29
CC057/UncJ f 61.0 73.54   2   52.0 1.2056 9.0, 113.0 -0.04
CC057/UncJ m 3.5 2.1213   2   1.5 0.6061 2.0, 5.0 -0.37
CC059/TauUncJ f 109.5 135.2   4 67.59 1.2345 21.0, 311.0 0.6
CC059/TauUncJ m 1341.0 1335.0   3 770.5 0.9949 7.0, 2676.0 6.25
CC060/UncJ m 62.0 0.0   1   0.0 0.0 62.0, 62.0 -0.08
CC061/GeniUncJ f 71.5 95.46   2   67.5 1.3351 4.0, 139.0 0.1
CC061/GeniUncJ m 40.0 35.355   2   25.0 0.8839 15.0, 65.0 -0.19
CC068/TauUncJ f 0.0 0.0   2   0.0 None -0.84
CC068/TauUncJ m 0.0 0.0   2   0.0 None -0.39
CC074/UncJ f 0.0 0.0   1   0.0 None -0.84
CC074/UncJ m 7.0 0.0   1   0.0 0.0 7.0, 7.0 -0.35
CC075/UncJ f 1.0 0.0   1   0.0 0.0 1.0, 1.0 -0.83
CC078/TauUncJ f 326.0 446.9   2   316.0 1.3708 10.0, 642.0 3.47
CC078/TauUncJ m 474.0 285.8   3 165.0 0.603 287.0, 803.0 1.96
CC079/TauUncJ f 36.0 41.012   2   29.0 1.1392 7.0, 65.0 -0.37
CC079/TauUncJ m 4.0 1.4142   2   1.0 0.3536 3.0, 5.0 -0.37
CC080/TauUncJ f 0.0 0.0   2   0.0 None -0.84
CC084/TauJ f 72.5 4.9497   2   3.5 0.0683 69.0, 76.0 0.11
CC084/TauJ m 30.0 0.0   1   0.0 0.0 30.0, 30.0 -0.24
NOD/ShiLtJ f 34.0 48.924   11 14.751 1.439 -0.4
NOD/ShiLtJ m 15.5 13.308   6 5.4329 0.8586 2.0, 37.0 -0.31
NZO/HlLtJ f 10.6 7.8627   10 2.4864 0.7418 1.0, 22.0 -0.7
NZO/HlLtJ m 13.6 12.501   10 3.9531 0.9192 3.0, 37.0 -0.32
PWK/PhJ f 24.714 12.566   7 4.7495 0.5085 11.0, 47.0 -0.52
PWK/PhJ m 22.5 11.327   6 4.6242 0.5034 6.0, 37.0 -0.28
WSB/EiJ f 39.0 45.211   3 26.102 1.1592 1.0, 89.0 -0.33
WSB/EiJ m 28.8 30.327   5 13.562 1.053 3.0, 77.0 -0.25


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J f 10.2222222222 51.4160091459 111.5064970438 -91.0620525993
A/J m 129.5714285714 58.3002744032 244.4170012426 14.7258559003
C57BL/6J f 42.5 44.5275700815 130.2147549993 -45.2147549993
C57BL/6J m 10.8461538462 42.7807055435 95.1197645232 -73.4274568309
CC001/UncJ f 28.0 89.0551401631 203.4295099987 -147.4295099987
CC001/UncJ m 117.0 77.1240137188 268.9264122323 -34.9264122323
CC002/UncJ f 213.6666666667 89.0551401631 389.0961766654 38.237156668
CC002/UncJ m 20.0 109.0698261858 234.8563926616 -194.8563926616
CC003/UncJ f 168.0 109.0698261858 382.8563926616 -46.8563926616
CC003/UncJ m 5.25 77.1240137188 157.1764122323 -146.6764122323
CC004/TauUncJ f 108.2222222222 51.4160091459 209.5064970438 6.9379474007
CC004/TauUncJ m 103.1052631579 35.3869244127 172.8138818711 33.3966444447
CC005/TauUncJ f 18.75 77.1240137188 170.6764122323 -133.1764122323
CC005/TauUncJ m 2.5 109.0698261858 217.3563926616 -212.3563926616
CC006/TauUncJ f 67.5 109.0698261858 282.3563926616 -147.3563926616
CC006/TauUncJ m 40.5 109.0698261858 255.3563926616 -174.3563926616
CC007/UncJ f 3.5 109.0698261858 218.3563926616 -211.3563926616
CC007/UncJ m 6.0 89.0551401631 181.4295099987 -169.4295099987
CC008/GeniUncJ f 5.5 109.0698261858 220.3563926616 -209.3563926616
CC008/GeniUncJ m 19.5 109.0698261858 234.3563926616 -195.3563926616
CC009/UncJ f 42.3333333333 89.0551401631 217.762843332 -133.0961766654
CC009/UncJ m 0.6666666667 89.0551401631 176.0961766654 -174.762843332
CC011/UncJ f 73.6666666667 89.0551401631 249.0961766654 -101.762843332
CC011/UncJ m 80.3333333333 89.0551401631 255.762843332 -95.0961766654
CC013/GeniUncJ f 259.0 89.0551401631 434.4295099987 83.5704900013
CC013/GeniUncJ m 110.3333333333 89.0551401631 285.762843332 -65.0961766654
CC016/GeniUncJ f 26.5 109.0698261858 241.3563926616 -188.3563926616
CC016/GeniUncJ m 1.5 109.0698261858 216.3563926616 -213.3563926616
CC017/UncJ f 14.6666666667 89.0551401631 190.0961766654 -160.762843332
CC017/UncJ m 0.75 77.1240137188 152.6764122323 -151.1764122323
CC018/UncJ f 121.0 89.0551401631 296.4295099987 -54.4295099987
CC018/UncJ m 68.4 68.9818149492 204.2871141316 -67.4871141316
CC019/TauUncJ f 167.2 68.9818149492 303.0871141316 31.3128858684
CC019/TauUncJ m 67.0 89.0551401631 242.4295099987 -108.4295099987
CC023/GeniUncJ f 22.3333333333 89.0551401631 197.762843332 -153.0961766654
CC023/GeniUncJ m 20.0 89.0551401631 195.4295099987 -155.4295099987
CC024/GeniUncJ f 20.5 109.0698261858 235.3563926616 -194.3563926616
CC024/GeniUncJ m 51.0 109.0698261858 265.8563926616 -163.8563926616
CC026/GeniUncJ f 12.0 68.9818149492 147.8871141317 -123.8871141316
CC026/GeniUncJ m 3.0 89.0551401631 178.4295099987 -172.4295099987
CC027/GeniUncJ f 145.25 77.1240137188 297.1764122323 -6.6764122323
CC027/GeniUncJ m 16.0 77.1240137188 167.9264122323 -135.9264122323
CC028/GeniUncJ f 133.0 77.1240137188 284.9264122323 -18.9264122323
CC028/GeniUncJ m 58.4 68.9818149492 194.2871141316 -77.4871141317
CC030/GeniUncJ f 94.5 109.0698261858 309.3563926616 -120.3563926616
CC030/GeniUncJ m 134.5 109.0698261858 349.3563926616 -80.3563926616
CC032/GeniUncJ f 58.0 89.0551401631 233.4295099987 -117.4295099987
CC032/GeniUncJ m 16.5 77.1240137188 168.4264122323 -135.4264122323
CC035/UncJ f 6.3333333333 89.0551401631 181.762843332 -169.0961766654
CC035/UncJ m 50.5 109.0698261858 265.3563926616 -164.3563926616
CC036/UncJ f 165.6666666667 89.0551401631 341.0961766654 -9.762843332
CC036/UncJ m 439.5 109.0698261858 654.3563926616 224.6436073384
CC040/TauUncJ f 2.5 109.0698261858 217.3563926616 -212.3563926616
CC040/TauUncJ m 2.5 109.0698261858 217.3563926616 -212.3563926616
CC041/TauUncJ f 0.0 109.0698261858 214.8563926616 -214.8563926616
CC041/TauUncJ m 1.0833333333 44.5275700815 88.7980883327 -86.631421666
CC044/UncJ f 2.0 109.0698261858 216.8563926616 -212.8563926616
CC044/UncJ m 38.0 109.0698261858 252.8563926616 -176.8563926616
CC051/TauUncJ f 15.0 109.0698261858 229.8563926616 -199.8563926616
CC051/TauUncJ m 19.6666666667 89.0551401631 195.0961766654 -155.762843332
CC057/UncJ f 61.0 109.0698261858 275.8563926616 -153.8563926616
CC057/UncJ m 3.5 109.0698261858 218.3563926616 -211.3563926616
CC059/TauUncJ f 109.5 77.1240137188 261.4264122323 -42.4264122323
CC059/TauUncJ m 1341.3333333333 89.0551401631 1516.762843332 1165.9038233346
CC061/GeniUncJ f 71.5 109.0698261858 286.3563926616 -143.3563926616
CC061/GeniUncJ m 40.0 109.0698261858 254.8563926616 -174.8563926616
CC068/TauUncJ f 0.0 109.0698261858 214.8563926616 -214.8563926616
CC068/TauUncJ m 0.0 109.0698261858 214.8563926616 -214.8563926616
CC078/TauUncJ f 326.0 109.0698261858 540.8563926616 111.1436073384
CC078/TauUncJ m 474.0 89.0551401631 649.4295099987 298.5704900013
CC079/TauUncJ f 36.0 109.0698261858 250.8563926616 -178.8563926616
CC079/TauUncJ m 4.0 109.0698261858 218.8563926616 -210.8563926616
NOD/ShiLtJ f 34.0 46.5075301512 125.6150736581 -57.6150736581
NOD/ShiLtJ m 15.5 62.9714935088 139.5473961403 -108.5473961403
NZO/HlLtJ f 10.6 48.7775091291 106.6866998784 -85.4866998784
NZO/HlLtJ m 13.6 48.7775091291 109.6866998784 -82.4866998784
PWK/PhJ f 24.7142857143 58.3002744032 139.5598583854 -90.1312869569
PWK/PhJ m 22.5 62.9714935088 146.5473961403 -101.5473961403
WSB/EiJ f 39.0 89.0551401631 214.4295099987 -136.4295099987
WSB/EiJ m 28.8 68.9818149492 164.6871141316 -107.0871141316


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
A/J both 69.8968253968 38.8668496021 146.4605405109 -6.6668897173
C57BL/6J both 26.6730769231 30.8743148271 87.4923166856 -34.1461628394
CC001/UncJ both 72.5 58.9044384609 188.5357140196 -43.5357140196
CC002/UncJ both 116.8333333333 70.4042700652 255.5225384341 -21.8558717675
CC003/UncJ both 86.625 66.7913551223 218.197132499 -44.947132499
CC004/TauUncJ both 105.6637426901 31.2083338865 167.1409658077 44.1865195724
CC005/TauUncJ both 10.625 66.7913551223 142.197132499 -120.947132499
CC006/TauUncJ both 54.0 77.1240137188 205.9264122323 -97.9264122323
CC007/UncJ both 4.75 70.4042700652 143.4392051008 -133.9392051008
CC008/GeniUncJ both 12.5 77.1240137188 164.4264122323 -139.4264122323
CC009/UncJ both 21.5 62.9714935088 145.5473961403 -102.5473961403
CC011/UncJ both 77.0 62.9714935088 201.0473961403 -47.0473961403
CC013/GeniUncJ both 184.6666666667 62.9714935088 308.714062807 60.6192705264
CC016/GeniUncJ both 14.0 77.1240137188 165.9264122323 -137.9264122323
CC017/UncJ both 7.7083333333 58.9044384609 123.7440473529 -108.3273806863
CC018/UncJ both 94.7 56.3234160522 205.6513640806 -16.2513640806
CC019/TauUncJ both 117.1 56.3234160522 228.0513640806 6.1486359194
CC023/GeniUncJ both 21.1666666667 62.9714935088 145.214062807 -102.8807294736
CC024/GeniUncJ both 35.75 77.1240137188 187.6764122323 -116.1764122323
CC026/GeniUncJ both 7.5 56.3234160522 118.4513640806 -103.4513640806
CC027/GeniUncJ both 80.625 54.5349130929 188.0531963308 -26.8031963308
CC028/GeniUncJ both 95.7 51.7363612119 197.6153355987 -6.2153355987
CC030/GeniUncJ both 114.5 77.1240137188 266.4264122323 -37.4264122323
CC032/GeniUncJ both 37.25 58.9044384609 153.2857140196 -78.7857140196
CC035/UncJ both 28.4166666667 70.4042700652 167.1058717675 -110.2725384341
CC036/UncJ both 302.5833333333 70.4042700652 441.2725384341 163.8941282325
CC040/TauUncJ both 2.5 77.1240137188 154.4264122323 -149.4264122323
CC041/TauUncJ both 0.5416666667 58.9044384609 116.5773806863 -115.4940473529
CC044/UncJ both 20.0 77.1240137188 171.9264122323 -131.9264122323
CC051/TauUncJ both 17.3333333333 70.4042700652 156.0225384341 -121.3558717675
CC057/UncJ both 32.25 77.1240137188 184.1764122323 -119.6764122323
CC059/TauUncJ both 725.4166666667 58.9044384609 841.4523806863 609.3809526471
CC061/GeniUncJ both 55.75 77.1240137188 207.6764122323 -96.1764122323
CC068/TauUncJ both 0.0 77.1240137188 151.9264122323 -151.9264122323
CC078/TauUncJ both 400.0 70.4042700652 538.6892051008 261.3107948992
CC079/TauUncJ both 20.0 77.1240137188 171.9264122323 -131.9264122323
NOD/ShiLtJ both 24.75 39.1419192027 101.8555740699 -52.3555740699
NZO/HlLtJ both 12.1 34.4909074746 80.0435570658 -55.8435570658
PWK/PhJ both 23.6071428571 42.9078401642 108.1311957228 -60.9169100085
WSB/EiJ both 33.9 56.3234160522 144.8513640806 -77.0513640806




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA