Project measure / variable:   CSNA03   reinstatement_active_cc_s1

ID, description, units MPD:110418   reinstatement_active_cc_s1   reinstatement, active lever presses (intravenous self administration), CC   [n]  session 1  
cocaine study
Data set, strains CSNA03   CC w/par   54 strains     sex: both     age:
Procedure operant conditioning chamber
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  STRAIN COMPARISON PLOT
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CSNA03 - reinstatement, active lever presses (intravenous self administration), CC session 1



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested52 strains51 strains
Mean of the strain means290.9   n 103.0   n
Median of the strain means94.0   n 65.5   n
SD of the strain means± 753.1 ± 159.6
Coefficient of variation (CV)2.5887 1.55
Min–max range of strain means1.0   –   4993.0   n 0.0   –   1113.0   n
Mean sample size per strain3.2   mice 3.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 3250001.1143 3250001.1143 10.0628 0.0017
strain 39 56135501.379 1439371.8302 4.4566 < 0.0001
sex:strain 39 35872527.3413 919808.3934 2.848 < 0.0001
Residuals 240 77513291.553 322972.0481


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
A/J f 54.89 44.577   9 14.859 0.8121 -0.31
A/J m 40.857 44.33   7 16.755 1.085 -0.39
C57BL/6J f 195.8 175.2   12 50.57 0.8945 9.0, 643.0 -0.13
C57BL/6J m 61.0 44.972   13 12.473 0.7372 3.0, 169.0 -0.26
CAST/EiJ f 202.0 0.0   1   0.0 0.0 202.0, 202.0 -0.12
CAST/EiJ m 65.5 53.03   2   37.5 0.8097 28.0, 103.0 -0.23
CC001/UncJ f 31.0 8.0   3 4.6188 0.2581 23.0, 39.0 -0.35
CC001/UncJ m 179.5 212.5   4 106.2 1.1837 29.0, 494.0 0.48
CC002/UncJ f 4993.0 5308.0   3 3064.0 1.063 58.0, 10608.0 6.24
CC002/UncJ m 255.0 145.7   2   103.0 0.5712 152.0, 358.0 0.95
CC003/UncJ f 72.0 15.556   2   11.0 0.2161 61.0, 83.0 -0.29
CC003/UncJ m 17.5 12.369   4 6.1847 0.7068 1.0, 27.0 -0.54
CC004/TauUncJ f 253.1 166.7   9 55.55 0.6585 1.0, 447.0 -0.05
CC004/TauUncJ m 274.7 157.6   19 36.149 0.5736 21.0, 596.0 1.08
CC005/TauUncJ f 53.0 67.73   4 33.867 1.278 10.0, 154.0 -0.32
CC005/TauUncJ m 24.0 11.314   2   8.0 0.4714 16.0, 32.0 -0.49
CC006/TauUncJ f 138.0 21.213   2   15.0 0.1537 123.0, 153.0 -0.2
CC006/TauUncJ m 1113.0 1574.0   2   1113.0 1.4142 6.33
CC007/UncJ f 31.5 43.134   2   30.5 1.3693 1.0, 62.0 -0.34
CC007/UncJ m 57.0 67.13   3 38.76 1.1778 -0.29
CC008/GeniUncJ f 11.5 14.849   2   10.5 1.2912 1.0, 22.0 -0.37
CC008/GeniUncJ m 58.0 53.74   2   38.0 0.9266 20.0, 96.0 -0.28
CC009/UncJ f 92.33 108.7   3 62.77 1.1775 2.0, 213.0 -0.26
CC009/UncJ m 19.333 30.925   3 17.854 1.5996 -0.52
CC011/UncJ f 201.7 156.2   3 90.2 0.7747 58.0, 368.0 -0.12
CC011/UncJ m 81.67 18.502   3 10.682 0.2266 63.0, 100.0 -0.13
CC012/GeniUncJ f 198.0 0.0   1   0.0 0.0 198.0, 198.0 -0.12
CC012/GeniUncJ m 124.3 67.14   3 38.766 0.54 76.0, 201.0 0.13
CC013/GeniUncJ f 451.7 454.4   3 262.3 1.0059 8.0, 916.0 0.21
CC013/GeniUncJ m 71.33 32.021   3 18.487 0.4489 40.0, 104.0 -0.2
CC015/UncJ f 30.0 33.941   2   24.0 1.1314 6.0, 54.0 -0.35
CC015/UncJ m 56.0 0.0   1   0.0 0.0 56.0, 56.0 -0.29
CC016/GeniUncJ f 1106.0 1558.0   2   1102.0 1.4091 4.0, 2208.0 1.08
CC016/GeniUncJ m 13.5 17.678   2   12.5 1.3095 1.0, 26.0 -0.56
CC017/UncJ f 20.667 4.7258   3 2.7285 0.2287 17.0, 26.0 -0.36
CC017/UncJ m 3.75 1.5   4 0.75 0.4 2.0, 5.0 -0.62
CC018/UncJ f 265.7 224.8   3 129.8 0.8462 22.0, 465.0 -0.03
CC018/UncJ m 214.6 99.08   5 44.311 0.4617 93.0, 359.0 0.7
CC019/TauUncJ f 456.4 436.7   5 195.3 0.9569 61.0, 1171.0 0.22
CC019/TauUncJ m 104.3 82.4   3 47.576 0.7898 34.0, 195.0 0.01
CC020/GeniUncJ f 265.0 0.0   1   0.0 0.0 265.0, 265.0 -0.03
CC023/GeniUncJ f 37.333 32.868   3 18.977 0.8804 2.0, 67.0 -0.34
CC023/GeniUncJ m 59.0 46.893   3 27.074 0.7948 16.0, 109.0 -0.28
CC024/GeniUncJ f 123.5 174.7   2   123.5 1.4142 -0.22
CC024/GeniUncJ m 26.5 36.062   2   25.5 1.3608 1.0, 52.0 -0.48
CC025/GeniUncJ f 79.0 107.5   2   76.0 1.3605 3.0, 155.0 -0.28
CC025/GeniUncJ m 71.0 0.0   1   0.0 0.0 71.0, 71.0 -0.2
CC026/GeniUncJ f 32.4 20.182   5 9.0255 0.6229 9.0, 64.0 -0.34
CC026/GeniUncJ m 26.333 13.577   3 7.8387 0.5156 12.0, 39.0 -0.48
CC027/GeniUncJ f 294.5 420.1   4 210.1 1.4265 27.0, 911.0 0.0
CC027/GeniUncJ m 90.0 86.49   4 43.245 0.961 14.0, 211.0 -0.08
CC028/GeniUncJ f 181.2 148.0   4 74.02 0.8168 65.0, 398.0 -0.15
CC028/GeniUncJ m 96.0 73.08   5 32.682 0.7612 48.0, 219.0 -0.04
CC029/UncJ f 1.0 0.0   1   0.0 0.0 1.0, 1.0 -0.38
CC029/UncJ m 8.0 0.0   1   0.0 0.0 8.0, 8.0 -0.6
CC030/GeniUncJ f 311.5 72.83   2   51.5 0.2338 260.0, 363.0 0.03
CC030/GeniUncJ m 135.5 139.3   2   98.5 1.028 37.0, 234.0 0.2
CC032/GeniUncJ f 64.33 10.599   3 6.1192 0.1647 53.0, 74.0 -0.3
CC032/GeniUncJ m 167.8 270.7   4 135.3 1.6136 11.0, 571.0 0.41
CC033/GeniUncJ f 54.0 0.0   1   0.0 0.0 54.0, 54.0 -0.31
CC033/GeniUncJ m 46.0 32.527   2   23.0 0.7071 23.0, 69.0 -0.36
CC035/UncJ f 41.333 19.858   3 11.465 0.4804 24.0, 63.0 -0.33
CC035/UncJ m 182.0 181.0   2   128.0 0.9946 54.0, 310.0 0.49
CC036/UncJ f 229.3 75.58   3 43.636 0.3296 166.0, 313.0 -0.08
CC036/UncJ m 148.0 118.8   2   84.0 0.8027 64.0, 232.0 0.28
CC037/TauUncJ f 50.0 0.0   1   0.0 0.0 50.0, 50.0 -0.32
CC037/TauUncJ m 0.0 0.0   1   0.0 None -0.65
CC040/TauUncJ f 46.0 65.05   2   46.0 1.4142 -0.33
CC040/TauUncJ m 95.0 29.698   2   21.0 0.3126 74.0, 116.0 -0.05
CC041/TauUncJ f 5.5 7.7782   2   5.5 1.4142 -0.38
CC041/TauUncJ m 3.25 6.635   12 1.9153 2.0415 -0.62
CC043/GeniUncJ m 24.0 0.0   1   0.0 0.0 24.0, 24.0 -0.49
CC044/UncJ f 4.0 5.6569   2   4.0 1.4142 -0.38
CC044/UncJ m 61.5 79.9   2   56.5 1.2992 5.0, 118.0 -0.26
CC051/TauUncJ f 56.0 55.15   2   39.0 0.9849 17.0, 95.0 -0.31
CC051/TauUncJ m 70.0 37.162   3 21.455 0.5309 31.0, 105.0 -0.21
CC057/UncJ f 776.0 1079.0   2   763.0 1.3905 13.0, 1539.0 0.64
CC057/UncJ m 24.5 6.364   2   4.5 0.2598 20.0, 29.0 -0.49
CC059/TauUncJ f 2260.0 1894.0   4 946.8 0.8378 35.0, 4199.0 2.61
CC059/TauUncJ m 140.0 52.72   3 30.436 0.3765 93.0, 197.0 0.23
CC060/UncJ m 85.0 0.0   1   0.0 0.0 85.0, 85.0 -0.11
CC061/GeniUncJ f 208.5 219.9   2   155.5 1.0547 53.0, 364.0 -0.11
CC061/GeniUncJ m 196.5 183.1   2   129.5 0.932 67.0, 326.0 0.59
CC068/TauUncJ f 1.0 1.4142   2   1.0 1.4142 -0.38
CC068/TauUncJ m 0.5 0.70711   2   0.5 1.4142 -0.64
CC074/UncJ f 12.0 0.0   1   0.0 0.0 12.0, 12.0 -0.37
CC074/UncJ m 77.0 0.0   1   0.0 0.0 77.0, 77.0 -0.16
CC075/UncJ f 5.0 0.0   1   0.0 0.0 5.0, 5.0 -0.38
CC078/TauUncJ f 449.5 596.1   2   421.5 1.3261 28.0, 871.0 0.21
CC078/TauUncJ m 233.0 114.8   3 66.25 0.4925 101.0, 309.0 0.81
CC079/TauUncJ f 185.5 30.406   2   21.5 0.1639 164.0, 207.0 -0.14
CC079/TauUncJ m 30.0 33.941   2   24.0 1.1314 6.0, 54.0 -0.46
CC080/TauUncJ f 8.5 12.021   2   8.5 1.4142 -0.38
CC084/TauJ f 132.5 95.46   2   67.5 0.7204 65.0, 200.0 -0.21
CC084/TauJ m 43.0 0.0   1   0.0 0.0 43.0, 43.0 -0.38
NOD/ShiLtJ f 106.7 105.7   11 31.883 0.9908 4.0, 351.0 -0.24
NOD/ShiLtJ m 62.0 44.371   6 18.114 0.7157 10.0, 114.0 -0.26
NZO/HlLtJ f 48.2 37.273   10 11.787 0.7733 7.0, 103.0 -0.32
NZO/HlLtJ m 52.8 34.628   10 10.95 0.6558 11.0, 127.0 -0.31
PWK/PhJ f 103.4 75.63   7 28.585 0.7312 29.0, 253.0 -0.25
PWK/PhJ m 93.83 52.5   6 21.433 0.5595 15.0, 144.0 -0.06
WSB/EiJ f 95.67 82.95   3 47.893 0.8671 3.0, 163.0 -0.26
WSB/EiJ m 69.4 51.83   5 23.181 0.7469 18.0, 129.0 -0.21


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J f 54.8888888889 189.4354326053 428.0572995778 -318.2795218001
A/J m 40.8571428571 214.7995903618 463.9903479264 -382.2760622121
C57BL/6J f 195.8333333333 164.0558970131 519.0066568798 -127.3399902132
C57BL/6J m 61.0 157.6198074573 371.4948859513 -249.4948859513
CC001/UncJ f 31.0 328.1117940262 677.346647093 -615.346647093
CC001/UncJ m 179.5 284.153148908 739.2526160334 -380.2526160334
CC002/UncJ f 4993.3333333334 328.1117940262 5639.6799804264 4346.9866862404
CC002/UncJ m 255.0 401.8532369767 1046.6097411683 -536.6097411683
CC003/UncJ f 72.0 401.8532369767 863.6097411683 -719.6097411683
CC003/UncJ m 17.5 284.153148908 577.2526160334 -542.2526160334
CC004/TauUncJ f 253.1111111111 189.4354326053 626.2795218001 -120.0572995779
CC004/TauUncJ m 274.6842105263 130.3784063767 531.5163249129 17.8520961398
CC005/TauUncJ f 53.0 284.153148908 612.7526160334 -506.7526160334
CC005/TauUncJ m 24.0 401.8532369767 815.6097411683 -767.6097411683
CC006/TauUncJ f 138.0 401.8532369767 929.6097411683 -653.6097411683
CC006/TauUncJ m 1113.0 401.8532369767 1904.6097411683 321.3902588317
CC007/UncJ f 31.5 401.8532369767 823.1097411683 -760.1097411683
CC007/UncJ m 57.0 328.1117940262 703.346647093 -589.346647093
CC008/GeniUncJ f 11.5 401.8532369767 803.1097411683 -780.1097411683
CC008/GeniUncJ m 58.0 401.8532369767 849.6097411683 -733.6097411683
CC009/UncJ f 92.3333333333 328.1117940262 738.6799804264 -554.0133137597
CC009/UncJ m 19.3333333333 328.1117940262 665.6799804264 -627.0133137597
CC011/UncJ f 201.6666666667 328.1117940262 848.0133137597 -444.6799804264
CC011/UncJ m 81.6666666667 328.1117940262 728.0133137597 -564.6799804264
CC013/GeniUncJ f 451.6666666667 328.1117940262 1098.0133137597 -194.6799804264
CC013/GeniUncJ m 71.3333333333 328.1117940262 717.6799804264 -575.0133137597
CC016/GeniUncJ f 1106.0 401.8532369767 1897.6097411683 314.3902588317
CC016/GeniUncJ m 13.5 401.8532369767 805.1097411683 -778.1097411683
CC017/UncJ f 20.6666666667 328.1117940262 667.0133137597 -625.6799804264
CC017/UncJ m 3.75 284.153148908 563.5026160334 -556.0026160334
CC018/UncJ f 265.6666666667 328.1117940262 912.0133137597 -380.6799804264
CC018/UncJ m 214.6 254.1543027916 715.2579600137 -286.0579600136
CC019/TauUncJ f 456.4 254.1543027916 957.0579600136 -44.2579600137
CC019/TauUncJ m 104.3333333333 328.1117940262 750.6799804263 -542.0133137597
CC023/GeniUncJ f 37.3333333333 328.1117940262 683.6799804263 -609.0133137597
CC023/GeniUncJ m 59.0 328.1117940262 705.346647093 -587.346647093
CC024/GeniUncJ f 123.5 401.8532369767 915.1097411683 -668.1097411683
CC024/GeniUncJ m 26.5 401.8532369767 818.1097411683 -765.1097411683
CC026/GeniUncJ f 32.4 254.1543027916 533.0579600137 -468.2579600137
CC026/GeniUncJ m 26.3333333333 328.1117940262 672.6799804264 -620.0133137597
CC027/GeniUncJ f 294.5 284.153148908 854.2526160335 -265.2526160334
CC027/GeniUncJ m 90.0 284.153148908 649.7526160334 -469.7526160334
CC028/GeniUncJ f 181.25 284.153148908 741.0026160334 -378.5026160334
CC028/GeniUncJ m 96.0 254.1543027916 596.6579600137 -404.6579600137
CC030/GeniUncJ f 311.5 401.8532369767 1103.1097411683 -480.1097411683
CC030/GeniUncJ m 135.5 401.8532369767 927.1097411683 -656.1097411683
CC032/GeniUncJ f 64.3333333333 328.1117940262 710.6799804263 -582.0133137597
CC032/GeniUncJ m 167.75 284.153148908 727.5026160334 -392.0026160334
CC035/UncJ f 41.3333333333 328.1117940262 687.6799804264 -605.0133137597
CC035/UncJ m 182.0 401.8532369767 973.6097411683 -609.6097411683
CC036/UncJ f 229.3333333333 328.1117940262 875.6799804264 -417.0133137597
CC036/UncJ m 148.0 401.8532369767 939.6097411683 -643.6097411683
CC040/TauUncJ f 46.0 401.8532369767 837.6097411683 -745.6097411683
CC040/TauUncJ m 95.0 401.8532369767 886.6097411683 -696.6097411683
CC041/TauUncJ f 5.5 401.8532369767 797.1097411683 -786.1097411683
CC041/TauUncJ m 3.25 164.0558970131 326.4233235465 -319.9233235465
CC044/UncJ f 4.0 401.8532369767 795.6097411683 -787.6097411683
CC044/UncJ m 61.5 401.8532369767 853.1097411683 -730.1097411683
CC051/TauUncJ f 56.0 401.8532369767 847.6097411683 -735.6097411683
CC051/TauUncJ m 70.0 328.1117940262 716.346647093 -576.346647093
CC057/UncJ f 776.0 401.8532369767 1567.6097411683 -15.6097411683
CC057/UncJ m 24.5 401.8532369767 816.1097411683 -767.1097411683
CC059/TauUncJ f 2260.25 284.153148908 2820.0026160334 1700.4973839665
CC059/TauUncJ m 140.0 328.1117940262 786.346647093 -506.346647093
CC061/GeniUncJ f 208.5 401.8532369767 1000.1097411683 -583.1097411683
CC061/GeniUncJ m 196.5 401.8532369767 988.1097411683 -595.1097411683
CC068/TauUncJ f 1.0 401.8532369767 792.6097411683 -790.6097411683
CC068/TauUncJ m 0.5 401.8532369767 792.1097411683 -791.1097411683
CC078/TauUncJ f 449.5 401.8532369767 1241.1097411683 -342.1097411683
CC078/TauUncJ m 233.0 328.1117940262 879.346647093 -413.346647093
CC079/TauUncJ f 185.5 401.8532369767 977.1097411683 -606.1097411683
CC079/TauUncJ m 30.0 401.8532369767 821.6097411683 -761.6097411683
NOD/ShiLtJ f 106.7272727273 171.3507959865 444.2708005096 -230.8162550551
NOD/ShiLtJ m 62.0 232.0100745432 519.0360971567 -395.0360971567
NZO/HlLtJ f 48.2 179.7142309716 402.2186385807 -305.8186385807
NZO/HlLtJ m 52.8 179.7142309716 406.8186385807 -301.2186385807
PWK/PhJ f 103.4285714286 214.7995903618 526.5617764978 -319.7046336407
PWK/PhJ m 93.8333333333 232.0100745432 550.86943049 -363.2027638233
WSB/EiJ f 95.6666666667 328.1117940262 742.0133137597 -550.6799804264
WSB/EiJ m 69.4 254.1543027916 570.0579600137 -431.2579600137


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
A/J both 47.873015873 143.1997269079 329.9618192525 -234.2157875065
C57BL/6J both 128.4166666667 113.7522978313 352.4970491492 -95.6637158158
CC001/UncJ both 105.25 217.0255523052 532.7681222371 -322.2681222371
CC002/UncJ both 2624.1666666667 259.3951490717 3135.1485573734 2113.18477596
CC003/UncJ both 44.75 246.0838455197 529.5099853198 -440.0099853198
CC004/TauUncJ both 263.8976608187 114.9829465352 490.4022952726 37.3930263648
CC005/TauUncJ both 38.5 246.0838455197 523.2599853198 -446.2599853198
CC006/TauUncJ both 625.5 284.153148908 1185.2526160335 65.7473839666
CC007/UncJ both 44.25 259.3951490717 555.2318907067 -466.7318907067
CC008/GeniUncJ both 34.75 284.153148908 594.5026160335 -525.0026160335
CC009/UncJ both 55.8333333333 232.0100745432 512.86943049 -401.2027638233
CC011/UncJ both 141.6666666667 232.0100745432 598.7027638233 -315.36943049
CC013/GeniUncJ both 261.5 232.0100745432 718.5360971567 -195.5360971567
CC016/GeniUncJ both 559.75 284.153148908 1119.5026160334 -0.0026160334
CC017/UncJ both 12.2083333333 217.0255523052 439.7264555705 -415.3097889038
CC018/UncJ both 240.1333333333 207.5161192574 648.9188458987 -168.6521792321
CC019/TauUncJ both 280.3666666667 207.5161192574 689.1521792321 -128.4188458987
CC023/GeniUncJ both 48.1666666667 232.0100745432 505.2027638233 -408.86943049
CC024/GeniUncJ both 75.0 284.153148908 634.7526160335 -484.7526160335
CC026/GeniUncJ both 29.3666666667 207.5161192574 438.1521792321 -379.4188458987
CC027/GeniUncJ both 192.25 200.9266184884 588.0548705842 -203.5548705842
CC028/GeniUncJ both 138.625 190.6157270937 514.1184700102 -236.8684700102
CC030/GeniUncJ both 223.5 284.153148908 783.2526160334 -336.2526160334
CC032/GeniUncJ both 116.0416666667 217.0255523052 543.5597889038 -311.4764555705
CC035/UncJ both 111.6666666667 259.3951490717 622.6485573734 -399.3152240401
CC036/UncJ both 188.6666666667 259.3951490717 699.6485573734 -322.3152240401
CC040/TauUncJ both 70.5 284.153148908 630.2526160334 -489.2526160335
CC041/TauUncJ both 4.375 217.0255523052 431.8931222371 -423.1431222371
CC044/UncJ both 32.75 284.153148908 592.5026160334 -527.0026160335
CC051/TauUncJ both 63.0 259.3951490717 573.9818907067 -447.9818907067
CC057/UncJ both 400.25 284.153148908 960.0026160335 -159.5026160334
CC059/TauUncJ both 1200.125 217.0255523052 1627.6431222371 772.6068777629
CC061/GeniUncJ both 202.5 284.153148908 762.2526160334 -357.2526160334
CC068/TauUncJ both 0.75 284.153148908 560.5026160334 -559.0026160335
CC078/TauUncJ both 341.25 259.3951490717 852.2318907067 -169.7318907067
CC079/TauUncJ both 107.75 284.153148908 667.5026160334 -452.0026160334
NOD/ShiLtJ both 84.3636363636 144.2131841882 368.4488468428 -199.7215741155
NZO/HlLtJ both 50.5 127.0771513958 300.8289800068 -199.8289800068
PWK/PhJ both 98.630952381 158.0882180217 410.0485591955 -212.7866544336
WSB/EiJ both 82.5333333333 207.5161192574 491.3188458987 -326.2521792321




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA