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Project measure / variable:   CSNA03   extinction_inactive_cc_s3

ID, description, units MPD:110411   extinction_inactive_cc_s3   extinction, inactive lever presses (intravenous self administration), CC   [n]  session 3  
cocaine study
Data set, strains CSNA03   CC w/par   54 strains     sex: both     age:
Procedure operant conditioning chamber
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  STRAIN COMPARISON PLOT
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CSNA03 - extinction, inactive lever presses (intravenous self administration), CC session 3



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested52 strains50 strains
Mean of the strain means70.13   n 64.24   n
Median of the strain means35.5   n 20.5   n
SD of the strain means± 110.5 ± 139.2
Coefficient of variation (CV)1.5752 2.1669
Min–max range of strain means0.0   –   629.0   n 0.0   –   786.3   n
Mean sample size per strain3.0   mice 3.5   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 6795.0634 6795.0634 0.3222 0.5709
strain 34 2777526.1506 81691.9456 3.8733 < 0.0001
sex:strain 34 568991.3736 16735.0404 0.7935 0.7872
Residuals 220 4640026.809 21091.0309


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
A/J f 8.625 14.242   8 5.0354 1.6513 -0.56
A/J m 26.429 29.938   7 11.316 1.1328 -0.27
C57BL/6J f 37.909 54.42   11 16.407 1.4354 -0.29
C57BL/6J m 9.0769 6.4351   13 1.7848 0.7089 -0.4
CAST/EiJ f 43.0 0.0   1   0.0 0.0 43.0, 43.0 -0.25
CAST/EiJ m 18.5 17.678   2   12.5 0.9555 6.0, 31.0 -0.33
CC001/UncJ f 28.667 31.182   3 18.003 1.0878 5.0, 64.0 -0.38
CC001/UncJ m 76.0 66.7   4 33.349 0.8776 15.0, 166.0 0.08
CC002/UncJ f 629.0 1019.0   3 588.2 1.6196 16.0, 1805.0 5.06
CC002/UncJ m 0.0 0.0   1   0.0 None -0.46
CC003/UncJ f 48.0 46.669   2   33.0 0.9723 15.0, 81.0 -0.2
CC003/UncJ m 16.0 13.229   3 7.6376 0.8268 6.0, 31.0 -0.35
CC004/TauUncJ f 92.89 123.2   9 41.074 1.3266 0.21
CC004/TauUncJ m 118.2 138.5   19 31.775 1.1722 12.0, 615.0 0.39
CC005/TauUncJ f 13.75 24.851   4 12.426 1.8074 -0.51
CC005/TauUncJ m 16.0 5.6569   2   4.0 0.3536 12.0, 20.0 -0.35
CC006/TauUncJ f 247.0 0.0   1   0.0 0.0 247.0, 247.0 1.6
CC006/TauUncJ m 38.5 54.45   2   38.5 1.4142 -0.18
CC007/UncJ f 7.5 10.607   2   7.5 1.4142 -0.57
CC007/UncJ m 19.667 20.551   3 11.865 1.045 -0.32
CC008/GeniUncJ f 5.5 7.7782   2   5.5 1.4142 -0.59
CC008/GeniUncJ m 52.5 57.28   2   40.5 1.091 12.0, 93.0 -0.08
CC009/UncJ f 37.0 45.398   3 26.211 1.227 1.0, 88.0 -0.3
CC009/UncJ m 5.3333 5.5076   3 3.1798 1.0327 -0.42
CC011/UncJ f 90.0 79.54   3 45.924 0.8838 3.0, 159.0 0.18
CC011/UncJ m 125.0 98.99   2   70.0 0.792 55.0, 195.0 0.44
CC012/GeniUncJ f 272.0 0.0   1   0.0 0.0 272.0, 272.0 1.83
CC012/GeniUncJ m 69.67 27.062   3 15.624 0.3884 48.0, 100.0 0.04
CC013/GeniUncJ f 191.7 166.6   3 96.16 0.869 37.0, 368.0 1.1
CC013/GeniUncJ m 94.33 36.116   3 20.851 0.3829 66.0, 135.0 0.22
CC015/UncJ f 0.0 0.0   1   0.0 None -0.63
CC015/UncJ m 92.0 0.0   1   0.0 0.0 92.0, 92.0 0.2
CC016/GeniUncJ f 17.0 11.314   2   8.0 0.6655 9.0, 25.0 -0.48
CC016/GeniUncJ m 1.0 1.4142   2   1.0 1.4142 -0.45
CC017/UncJ f 12.0 17.321   3 10.0 1.4434 2.0, 32.0 -0.53
CC017/UncJ m 1.5 1.9149   4 0.95743 1.2766 -0.45
CC018/UncJ f 108.0 115.2   3 66.52 1.0669 8.0, 234.0 0.34
CC018/UncJ m 46.2 23.102   5 10.332 0.5 12.0, 71.0 -0.13
CC019/TauUncJ f 65.0 50.54   5 22.601 0.7775 18.0, 124.0 -0.05
CC019/TauUncJ m 48.5 37.477   2   26.5 0.7727 22.0, 75.0 -0.11
CC020/GeniUncJ f 6.0 0.0   1   0.0 0.0 6.0, 6.0 -0.58
CC023/GeniUncJ f 63.33 78.01   3 45.042 1.2318 11.0, 153.0 -0.06
CC023/GeniUncJ m 30.0 48.508   3 28.006 1.6169 1.0, 86.0 -0.25
CC024/GeniUncJ f 41.0 57.98   2   41.0 1.4142 -0.26
CC024/GeniUncJ m 75.0 0.0   1   0.0 0.0 75.0, 75.0 0.08
CC025/GeniUncJ f 71.5 101.1   2   71.5 1.4142 0.01
CC026/GeniUncJ f 11.4 6.8775   5 3.0757 0.6033 6.0, 23.0 -0.53
CC026/GeniUncJ m 9.6667 4.9329   3 2.848 0.5103 4.0, 13.0 -0.39
CC027/GeniUncJ f 112.7 118.7   3 68.54 1.0536 13.0, 244.0 0.39
CC027/GeniUncJ m 8.5 11.03   4 5.5151 1.2977 2.0, 25.0 -0.4
CC028/GeniUncJ f 81.0 84.49   4 42.243 1.043 5.0, 167.0 0.1
CC028/GeniUncJ m 46.2 41.806   5 18.696 0.9049 10.0, 117.0 -0.13
CC029/UncJ f 2.0 0.0   1   0.0 0.0 2.0, 2.0 -0.62
CC029/UncJ m 16.0 0.0   1   0.0 0.0 16.0, 16.0 -0.35
CC030/GeniUncJ f 161.5 139.3   2   98.5 0.8625 63.0, 260.0 0.83
CC030/GeniUncJ m 57.5 74.25   2   52.5 1.2912 5.0, 110.0 -0.05
CC032/GeniUncJ f 29.0 7.9373   3 4.5826 0.2737 20.0, 35.0 -0.37
CC032/GeniUncJ m 30.0 20.216   4 10.108 0.6739 11.0, 58.0 -0.25
CC033/GeniUncJ f 1.0 0.0   1   0.0 0.0 1.0, 1.0 -0.63
CC033/GeniUncJ m 3.0 0.0   1   0.0 0.0 3.0, 3.0 -0.44
CC035/UncJ f 8.0 11.314   2   8.0 1.4142 -0.56
CC035/UncJ m 60.0 21.213   2   15.0 0.3536 45.0, 75.0 -0.03
CC036/UncJ f 112.3 88.15   3 50.89 0.7847 31.0, 206.0 0.38
CC036/UncJ m 288.5 51.62   2   36.5 0.1789 252.0, 325.0 1.61
CC037/TauUncJ f 48.0 0.0   1   0.0 0.0 48.0, 48.0 -0.2
CC037/TauUncJ m 0.0 0.0   1   0.0 None -0.46
CC040/TauUncJ f 3.0 0.0   1   0.0 0.0 3.0, 3.0 -0.61
CC040/TauUncJ m 17.0 11.314   2   8.0 0.6655 9.0, 25.0 -0.34
CC041/TauUncJ f 0.5 0.70711   2   0.5 1.4142 -0.63
CC041/TauUncJ m 0.91667 2.5746   12 0.74324 2.8087 -0.45
CC043/GeniUncJ m 11.0 0.0   1   0.0 0.0 11.0, 11.0 -0.38
CC044/UncJ f 18.0 0.0   1   0.0 0.0 18.0, 18.0 -0.47
CC044/UncJ m 8.0 11.314   2   8.0 1.4142 -0.4
CC051/TauUncJ f 34.0 32.527   2   23.0 0.9567 11.0, 57.0 -0.33
CC051/TauUncJ m 21.333 28.572   3 16.496 1.3393 1.0, 54.0 -0.31
CC057/UncJ f 30.0 32.527   2   23.0 1.0842 7.0, 53.0 -0.36
CC057/UncJ m 1.0 1.4142   2   1.0 1.4142 -0.45
CC059/TauUncJ f 190.0 183.7   3 106.1 0.9671 1.0, 368.0 1.09
CC059/TauUncJ m 595.7 900.9   3 520.1 1.5124 22.0, 1634.0 3.82
CC060/UncJ m 71.0 0.0   1   0.0 0.0 71.0, 71.0 0.05
CC061/GeniUncJ f 56.5 68.59   2   48.5 1.214 8.0, 105.0 -0.12
CC061/GeniUncJ m 70.0 84.85   2   60.0 1.2122 10.0, 130.0 0.04
CC068/TauUncJ f 0.0 0.0   2   0.0 None -0.63
CC068/TauUncJ m 0.0 0.0   2   0.0 None -0.46
CC074/UncJ f 1.0 0.0   1   0.0 0.0 1.0, 1.0 -0.63
CC074/UncJ m 2.0 0.0   1   0.0 0.0 2.0, 2.0 -0.45
CC075/UncJ f 5.0 0.0   1   0.0 0.0 5.0, 5.0 -0.59
CC078/TauUncJ f 375.5 292.0   2   206.5 0.7777 169.0, 582.0 2.76
CC078/TauUncJ m 786.3 986.2   3 569.4 1.2542 202.0, 1925.0 5.19
CC079/TauUncJ f 28.5 31.82   2   22.5 1.1165 6.0, 51.0 -0.38
CC079/TauUncJ m 24.5 26.163   2   18.5 1.0679 6.0, 43.0 -0.29
CC080/TauUncJ f 0.5 0.70711   2   0.5 1.4142 -0.63
CC084/TauJ f 99.5 79.9   2   56.5 0.803 43.0, 156.0 0.27
CC084/TauJ m 43.0 0.0   1   0.0 0.0 43.0, 43.0 -0.15
NOD/ShiLtJ f 48.273 102.6   11 30.923 2.1246 -0.2
NOD/ShiLtJ m 11.833 10.852   6 4.4303 0.9171 1.0, 31.0 -0.38
NZO/HlLtJ f 9.1 9.4334   10 2.9831 1.0366 -0.55
NZO/HlLtJ m 17.9 22.698   10 7.1778 1.2681 1.0, 74.0 -0.33
PWK/PhJ f 39.667 56.75   6 23.168 1.4307 5.0, 153.0 -0.28
PWK/PhJ m 17.857 12.362   7 4.6723 0.6923 7.0, 38.0 -0.33
WSB/EiJ f 4.5 0.70711   2   0.5 0.1571 4.0, 5.0 -0.59
WSB/EiJ m 14.0 11.619   5 5.1962 0.8299 5.0, 33.0 -0.36


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J f 8.625 51.3456801369 109.8173535587 -92.5673535587
A/J m 26.4285714286 54.8908409609 134.6077477651 -81.7506049079
C57BL/6J f 37.9090909091 43.7877431478 124.2062199828 -48.3880381646
C57BL/6J m 9.0769230769 40.278865378 88.4587362188 -70.3048900649
CC001/UncJ f 28.6666666667 83.8471445544 193.91308806 -136.5797547267
CC001/UncJ m 76.0 72.6137572189 219.1075988111 -67.1075988111
CC003/UncJ f 48.0 102.6913602738 250.3847071173 -154.3847071173
CC003/UncJ m 16.0 83.8471445544 181.2464213933 -149.2464213933
CC004/TauUncJ f 92.8888888889 48.4091714793 188.293954763 -2.5161769852
CC004/TauUncJ m 118.1578947368 33.3174768029 183.8201643442 52.4956251294
CC005/TauUncJ f 13.75 72.6137572189 156.8575988111 -129.3575988111
CC005/TauUncJ m 16.0 102.6913602738 218.3847071173 -186.3847071173
CC007/UncJ f 7.5 102.6913602738 209.8847071173 -194.8847071173
CC007/UncJ m 19.6666666667 83.8471445544 184.91308806 -145.5797547267
CC008/GeniUncJ f 5.5 102.6913602738 207.8847071173 -196.8847071173
CC008/GeniUncJ m 52.5 102.6913602738 254.8847071173 -149.8847071173
CC009/UncJ f 37.0 83.8471445544 202.2464213933 -128.2464213933
CC009/UncJ m 5.3333333333 83.8471445544 170.5797547267 -159.91308806
CC011/UncJ f 90.0 83.8471445544 255.2464213933 -75.2464213933
CC011/UncJ m 125.0 102.6913602738 327.3847071173 -77.3847071173
CC013/GeniUncJ f 191.6666666667 83.8471445544 356.91308806 26.4202452733
CC013/GeniUncJ m 94.3333333333 83.8471445544 259.5797547267 -70.91308806
CC016/GeniUncJ f 17.0 102.6913602738 219.3847071173 -185.3847071173
CC016/GeniUncJ m 1.0 102.6913602738 203.3847071173 -201.3847071173
CC017/UncJ f 12.0 83.8471445544 177.2464213933 -153.2464213933
CC017/UncJ m 1.5 72.6137572189 144.6075988111 -141.6075988111
CC018/UncJ f 108.0 83.8471445544 273.2464213933 -57.2464213933
CC018/UncJ m 46.2 64.9477188973 174.1993276154 -81.7993276154
CC019/TauUncJ f 65.0 64.9477188973 192.9993276154 -62.9993276154
CC019/TauUncJ m 48.5 102.6913602738 250.8847071173 -153.8847071173
CC023/GeniUncJ f 63.3333333333 83.8471445544 228.5797547267 -101.91308806
CC023/GeniUncJ m 30.0 83.8471445544 195.2464213933 -135.2464213933
CC026/GeniUncJ f 11.4 64.9477188973 139.3993276154 -116.5993276154
CC026/GeniUncJ m 9.6666666667 83.8471445544 174.91308806 -155.5797547267
CC027/GeniUncJ f 112.6666666667 83.8471445544 277.91308806 -52.5797547267
CC027/GeniUncJ m 8.5 72.6137572189 151.6075988111 -134.6075988111
CC028/GeniUncJ f 81.0 72.6137572189 224.1075988111 -62.1075988111
CC028/GeniUncJ m 46.2 64.9477188973 174.1993276154 -81.7993276154
CC030/GeniUncJ f 161.5 102.6913602738 363.8847071173 -40.8847071173
CC030/GeniUncJ m 57.5 102.6913602738 259.8847071173 -144.8847071173
CC032/GeniUncJ f 29.0 83.8471445544 194.2464213933 -136.2464213933
CC032/GeniUncJ m 30.0 72.6137572189 173.1075988111 -113.1075988111
CC035/UncJ f 8.0 102.6913602738 210.3847071173 -194.3847071173
CC035/UncJ m 60.0 102.6913602738 262.3847071173 -142.3847071173
CC036/UncJ f 112.3333333333 83.8471445544 277.5797547267 -52.91308806
CC036/UncJ m 288.5 102.6913602738 490.8847071173 86.1152928827
CC041/TauUncJ f 0.5 102.6913602738 202.8847071173 -201.8847071173
CC041/TauUncJ m 0.9166666667 41.9235722772 83.5398773633 -81.70654403
CC051/TauUncJ f 34.0 102.6913602738 236.3847071173 -168.3847071173
CC051/TauUncJ m 21.3333333333 83.8471445544 186.5797547267 -143.91308806
CC057/UncJ f 30.0 102.6913602738 232.3847071173 -172.3847071173
CC057/UncJ m 1.0 102.6913602738 203.3847071173 -201.3847071173
CC059/TauUncJ f 190.0 83.8471445544 355.2464213933 24.7535786067
CC059/TauUncJ m 595.6666666667 83.8471445544 760.91308806 430.4202452733
CC061/GeniUncJ f 56.5 102.6913602738 258.8847071173 -145.8847071173
CC061/GeniUncJ m 70.0 102.6913602738 272.3847071173 -132.3847071173
CC068/TauUncJ f 0.0 102.6913602738 202.3847071173 -202.3847071173
CC068/TauUncJ m 0.0 102.6913602738 202.3847071173 -202.3847071173
CC078/TauUncJ f 375.5 102.6913602738 577.8847071173 173.1152928827
CC078/TauUncJ m 786.3333333333 83.8471445544 951.5797547267 621.08691194
CC079/TauUncJ f 28.5 102.6913602738 230.8847071173 -173.8847071173
CC079/TauUncJ m 24.5 102.6913602738 226.8847071173 -177.8847071173
NOD/ShiLtJ f 48.2727272727 43.7877431478 134.5698563464 -38.0244018009
NOD/ShiLtJ m 11.8333333333 59.2888844976 128.6801984674 -105.0135318007
NZO/HlLtJ f 9.1 45.9249724548 99.6091925441 -81.4091925441
NZO/HlLtJ m 17.9 45.9249724548 108.4091925441 -72.6091925441
PWK/PhJ f 39.6666666667 59.2888844976 156.5135318007 -77.1801984674
PWK/PhJ m 17.8571428571 54.8908409609 126.0363191936 -90.3220334794
WSB/EiJ f 4.5 102.6913602738 206.8847071173 -197.8847071173
WSB/EiJ m 14.0 64.9477188973 141.9993276154 -113.9993276154


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
A/J both 17.5267857143 37.5811897434 91.5920046291 -56.5384332005
C57BL/6J both 23.493006993 29.747913566 82.1203614106 -35.1343474246
CC001/UncJ both 52.3333333333 55.4596731585 161.6335673459 -56.9669006792
CC003/UncJ both 32.0 66.2869880233 162.6387666987 -98.6387666987
CC004/TauUncJ both 105.5233918129 29.3832526443 163.4320704466 47.6147131791
CC005/TauUncJ both 14.875 62.8853584158 138.809816045 -109.059816045
CC007/UncJ both 13.5833333333 66.2869880233 144.2221000321 -117.0554333654
CC008/GeniUncJ both 29.0 72.6137572189 172.1075988111 -114.1075988111
CC009/UncJ both 21.1666666667 59.2888844976 138.0135318007 -95.6801984674
CC011/UncJ both 107.5 66.2869880233 238.1387666987 -23.1387666987
CC013/GeniUncJ both 143.0 59.2888844976 259.846865134 26.153134866
CC016/GeniUncJ both 9.0 72.6137572189 152.1075988111 -134.1075988111
CC017/UncJ both 6.75 55.4596731585 116.0502340125 -102.5502340125
CC018/UncJ both 77.1 53.0295904187 181.611013359 -27.411013359
CC019/TauUncJ both 56.75 60.7530280415 176.4824074185 -62.9824074185
CC023/GeniUncJ both 46.6666666667 59.2888844976 163.5135318007 -70.1801984674
CC026/GeniUncJ both 10.5333333333 53.0295904187 115.0443466923 -93.9776800257
CC027/GeniUncJ both 60.5833333333 55.4596731585 169.8835673459 -48.7169006792
CC028/GeniUncJ both 63.6 48.7107891729 159.5994957115 -32.3994957115
CC030/GeniUncJ both 109.5 72.6137572189 252.6075988111 -33.6075988111
CC032/GeniUncJ both 29.5 55.4596731585 138.8002340125 -79.8002340125
CC035/UncJ both 34.0 72.6137572189 177.1075988111 -109.1075988111
CC036/UncJ both 200.4166666667 66.2869880233 331.0554333654 69.7778999679
CC041/TauUncJ both 0.7083333333 55.4596731585 110.0085673459 -108.5919006792
CC051/TauUncJ both 27.6666666667 66.2869880233 158.3054333654 -102.9721000321
CC057/UncJ both 15.5 72.6137572189 158.6075988111 -127.6075988111
CC059/TauUncJ both 392.8333333333 59.2888844976 509.6801984674 275.9864681993
CC061/GeniUncJ both 63.25 72.6137572189 206.3575988111 -79.8575988111
CC068/TauUncJ both 0.0 72.6137572189 143.1075988111 -143.1075988111
CC078/TauUncJ both 580.9166666667 66.2869880233 711.5554333654 450.2778999679
CC079/TauUncJ both 26.5 72.6137572189 169.6075988111 -116.6075988111
NOD/ShiLtJ both 30.053030303 36.8528773468 102.6828870735 -42.5768264675
NZO/HlLtJ both 13.5 32.4738594486 77.4996638077 -50.4996638077
PWK/PhJ both 28.7619047619 40.3985650932 108.3796227719 -50.8558132481
WSB/EiJ both 9.25 60.7530280415 128.9824074185 -110.4824074185




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA