Project measure / variable:   CSNA03   extinction_active_cc_s8

ID, description, units MPD:110407   extinction_active_cc_s8   extinction, active lever presses (intravenous self administration), CC   [n]  session 8  
cocaine study
Data set, strains CSNA03   CC w/par   37 strains     sex: both     age:
Procedure operant conditioning chamber
Ontology mappings

  STRAIN COMPARISON PLOT
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CSNA03 - extinction, active lever presses (intravenous self administration), CC session 8



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested27 strains25 strains
Mean of the strain means479.4   n 164.8   n
Median of the strain means137.0   n 73.0   n
SD of the strain means± 991.9 ± 269.3
Coefficient of variation (CV)2.0692 1.6339
Min–max range of strain means11.0   –   4645.0   n 9.0   –   1365.0   n
Mean sample size per strain1.6   mice 1.6   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 5542955.6003 5542955.6003 12.4528 0.003
strain 4 6697710.6166 1674427.6542 3.7618 0.026
sex:strain 4 5021497.7231 1255374.4308 2.8203 0.0629
Residuals 15 6676747.5 445116.5


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
C57BL/6J f 137.0 0.0   1   0.0 0.0 137.0, 137.0 -0.35
CC001/UncJ f 11.0 0.0   1   0.0 0.0 11.0, 11.0 -0.47
CC001/UncJ m 362.0 369.1   2   261.0 1.0196 101.0, 623.0 0.73
CC002/UncJ f 4645.0 5705.0   3 3294.0 1.2283 10.0, 11016.0 4.2
CC003/UncJ f 18.0 0.0   1   0.0 0.0 18.0, 18.0 -0.47
CC003/UncJ m 9.0 0.0   1   0.0 0.0 9.0, 9.0 -0.58
CC004/TauUncJ f 381.0 0.0   1   0.0 0.0 381.0, 381.0 -0.1
CC004/TauUncJ m 273.0 143.0   7 54.05 0.5238 113.0, 532.0 0.4
CC005/TauUncJ f 42.0 0.0   1   0.0 0.0 42.0, 42.0 -0.44
CC006/TauUncJ m 1365.0 0.0   1   0.0 0.0 1365.0, 1365.0 4.46
CC007/UncJ f 245.0 0.0   1   0.0 0.0 245.0, 245.0 -0.24
CC007/UncJ m 160.5 152.0   2   107.5 0.9472 53.0, 268.0 -0.02
CC008/GeniUncJ m 31.5 16.263   2   11.5 0.5163 20.0, 43.0 -0.5
CC009/UncJ f 146.0 0.0   1   0.0 0.0 146.0, 146.0 -0.34
CC011/UncJ f 279.5 159.1   2   112.5 0.5692 167.0, 392.0 -0.2
CC011/UncJ m 65.5 34.648   2   24.5 0.529 41.0, 90.0 -0.37
CC012/GeniUncJ m 194.0 0.0   1   0.0 0.0 194.0, 194.0 0.11
CC013/GeniUncJ f 469.5 78.49   2   55.5 0.1672 414.0, 525.0 -0.01
CC013/GeniUncJ m 78.0 11.314   2   8.0 0.145 70.0, 86.0 -0.32
CC018/UncJ f 255.0 269.1   3 155.4 1.0553 17.0, 547.0 -0.23
CC018/UncJ m 127.0 28.036   4 14.018 0.2208 93.0, 160.0 -0.14
CC019/TauUncJ f 1079.0 983.6   3 567.9 0.9116 287.0, 2180.0 0.6
CC019/TauUncJ m 70.0 33.941   2   24.0 0.4849 46.0, 94.0 -0.35
CC023/GeniUncJ f 17.0 0.0   1   0.0 0.0 17.0, 17.0 -0.47
CC023/GeniUncJ m 291.0 0.0   1   0.0 0.0 291.0, 291.0 0.47
CC024/GeniUncJ f 80.0 0.0   1   0.0 0.0 80.0, 80.0 -0.4
CC025/GeniUncJ f 202.0 0.0   1   0.0 0.0 202.0, 202.0 -0.28
CC025/GeniUncJ m 73.0 0.0   1   0.0 0.0 73.0, 73.0 -0.34
CC027/GeniUncJ f 907.0 0.0   1   0.0 0.0 907.0, 907.0 0.43
CC028/GeniUncJ f 129.3 109.1   3 63.01 0.8439 51.0, 254.0 -0.35
CC028/GeniUncJ m 24.0 0.0   1   0.0 0.0 24.0, 24.0 -0.52
CC030/GeniUncJ m 152.0 0.0   1   0.0 0.0 152.0, 152.0 -0.05
CC032/GeniUncJ f 26.0 0.0   1   0.0 0.0 26.0, 26.0 -0.46
CC033/GeniUncJ m 33.0 0.0   1   0.0 0.0 33.0, 33.0 -0.49
CC036/UncJ f 108.3 89.86   3 51.88 0.8295 44.0, 211.0 -0.37
CC036/UncJ m 150.0 0.0   1   0.0 0.0 150.0, 150.0 -0.06
CC040/TauUncJ m 40.0 0.0   1   0.0 0.0 40.0, 40.0 -0.46
CC041/TauUncJ m 26.0 0.0   1   0.0 0.0 26.0, 26.0 -0.52
CC044/UncJ f 19.0 0.0   1   0.0 0.0 19.0, 19.0 -0.46
CC044/UncJ m 62.0 0.0   1   0.0 0.0 62.0, 62.0 -0.38
CC051/TauUncJ m 25.0 0.0   1   0.0 0.0 25.0, 25.0 -0.52
CC057/UncJ f 451.0 0.0   1   0.0 0.0 451.0, 451.0 -0.03
CC059/TauUncJ f 2678.0 1507.0   3 870.2 0.5628 1110.0, 4116.0 2.22
CC059/TauUncJ m 124.0 131.5   2   93.0 1.0607 31.0, 217.0 -0.15
CC060/UncJ m 69.0 0.0   1   0.0 0.0 69.0, 69.0 -0.36
CC061/GeniUncJ m 301.0 0.0   1   0.0 0.0 301.0, 301.0 0.51
CC078/TauUncJ f 373.0 0.0   1   0.0 0.0 373.0, 373.0 -0.11
CC078/TauUncJ m 15.0 0.0   1   0.0 0.0 15.0, 15.0 -0.56
CC079/TauUncJ f 103.0 39.598   2   28.0 0.3844 75.0, 131.0 -0.38
CC084/TauJ f 49.0 0.0   1   0.0 0.0 49.0, 49.0 -0.43
NOD/ShiLtJ f 17.0 0.0   1   0.0 0.0 17.0, 17.0 -0.47
WSB/EiJ f 75.0 39.598   2   28.0 0.528 47.0, 103.0 -0.41


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
CC011/UncJ f 279.5 471.7607974387 1285.0343373136 -726.0343373136
CC011/UncJ m 65.5 471.7607974387 1071.0343373136 -940.0343373136
CC013/GeniUncJ f 469.5 471.7607974387 1475.0343373136 -536.0343373136
CC013/GeniUncJ m 78.0 471.7607974387 1083.5343373136 -927.5343373136
CC018/UncJ f 255.0 385.1910781244 1076.015348422 -566.015348422
CC018/UncJ m 127.0 333.5852589669 838.0201486304 -584.0201486304
CC019/TauUncJ f 1079.0 385.1910781244 1900.015348422 257.984651578
CC019/TauUncJ m 70.0 471.7607974387 1075.5343373136 -935.5343373136
CC059/TauUncJ f 2678.0 385.1910781244 3499.015348422 1856.984651578
CC059/TauUncJ m 124.0 471.7607974387 1129.5343373136 -881.5343373136


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
CC011/UncJ both 172.5 333.5852589669 883.5201486304 -538.5201486304
CC013/GeniUncJ both 273.75 333.5852589669 984.7701486304 -437.2701486304
CC018/UncJ both 191.0 254.7799499895 734.0506086229 -352.0506086229
CC019/TauUncJ both 574.5 304.5202853123 1223.5696237426 -74.5696237426
CC059/TauUncJ both 1401.0 304.5202853123 2050.0696237426 751.9303762574




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA