Project measure / variable:   CSNA03   reinstatement_active_do_s2

ID, description, units MPD:110290   reinstatement_active_do_s2   reinstatement, active lever presses (intravenous self administration), DO   [n]  session 2  
cocaine study
Data set, strains CSNA03   DO population w/par   8 strains     sex: both     age:
Procedure operant conditioning chamber
Ontology mappings

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Distribution of Individual Animals with Boxplots.





  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means118.1   n 80.85   n
Median of the strain means117.3   n 69.37   n
SD of the strain means± 50.86 ± 28.638
Coefficient of variation (CV)0.4307 0.3542
Min–max range of strain means51.9   –   202.3   n 53.0   –   133.1   n
Mean sample size per strain43.2   mice 41.2   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 35280.6259 35280.6259 0.4274 0.5135
strain 6 297366.8423 49561.1404 0.6005 0.7301
sex:strain 6 81968.414 13661.4023 0.1655 0.9858
Residuals 659 54393094.6943 82538.8387


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
A/J f 64.44 65.34   9 21.781 1.0139 1.0, 210.0 -1.05
A/J m 61.43 51.61   7 19.506 0.8401 -0.68
C57BL/6J f 202.3 145.8   12 42.093 0.7207 19.0, 500.0 1.66
C57BL/6J m 76.23 60.46   13 16.768 0.7931 5.0, 229.0 -0.16
CAST/EiJ f 160.0 0.0   1   0.0 0.0 160.0, 160.0 0.82
CAST/EiJ m 66.5 72.83   2   51.5 1.0952 15.0, 118.0 -0.5
J:DO f 144.2 281.8   293 16.462 1.9548 0.51
J:DO m 133.1 330.4   281 19.71 2.4815 1.82
NOD/ShiLtJ f 87.27 141.3   11 42.595 1.6187 2.0, 482.0 -0.61
NOD/ShiLtJ m 70.33 50.31   6 20.537 0.7152 12.0, 136.0 -0.37
NZO/HlLtJ f 51.9 39.267   10 12.417 0.7566 -1.3
NZO/HlLtJ m 53.0 29.518   10 9.3345 0.557 9.0, 118.0 -0.97
PWK/PhJ f 130.9 77.99   7 29.479 0.596 60.0, 261.0 0.25
PWK/PhJ m 117.8 65.55   6 26.761 0.5563 32.0, 230.0 1.29
WSB/EiJ f 103.7 83.77   3 48.364 0.8081 7.0, 155.0 -0.28
WSB/EiJ m 68.4 39.488   5 17.66 0.5773 16.0, 113.0 -0.43


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J f 64.4444444444 95.7652446155 252.4862342872 -123.5973453983
A/J m 61.4285714286 108.5875806411 274.6479194335 -151.7907765763
C57BL/6J f 202.3333333333 82.9351346366 365.1823003103 39.4843663564
C57BL/6J m 76.2307692308 79.6814999696 232.6909958173 -80.2294573557
J:DO f 144.1535836177 16.7839959817 177.1101395978 111.1970276377
J:DO m 133.1494661922 17.1386266082 166.8023643369 99.4965680474
NOD/ShiLtJ f 87.2727272727 86.6229230035 257.3629259496 -82.8174714042
NOD/ShiLtJ m 70.3333333333 117.2879922004 300.6365510506 -159.9698843839
NZO/HlLtJ f 51.9 90.8508881004 230.2921053594 -126.4921053594
NZO/HlLtJ m 53.0 90.8508881004 231.3921053594 -125.3921053594
PWK/PhJ f 130.8571428571 108.5875806411 344.0764908621 -82.3622051478
PWK/PhJ m 117.8333333333 117.2879922004 348.1365510506 -112.4698843839
WSB/EiJ f 103.6666666667 165.8702692733 429.3646006205 -222.0312672872
WSB/EiJ m 68.4 128.4825581053 320.6845348195 -183.8845348195


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
A/J both 62.9365079365 72.3917204274 205.0827399398 -79.2097240668
C57BL/6J both 139.2820512821 57.5051693211 252.1974937035 26.3666088606
J:DO both 138.651524905 11.9941135889 162.2028100907 115.1002397192
NOD/ShiLtJ both 78.803030303 72.9040532208 221.9552637617 -64.3492031557
NZO/HlLtJ both 52.45 64.2412790526 178.5922674098 -73.6922674098
PWK/PhJ both 124.3452380952 79.9182954396 281.270429233 -32.5799530426
WSB/EiJ both 86.0333333333 104.9055694018 292.0227934344 -119.9561267677




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA