Project measure / variable:   CSNA03   reinstatement_active_do_s1

ID, description, units MPD:110289   reinstatement_active_do_s1   reinstatement, active lever presses (intravenous self administration), DO   [n]  session 1  
cocaine study
Data set, strains CSNA03   DO population w/par   8 strains     sex: both     age:
Procedure operant conditioning chamber
Ontology mappings

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Distribution of Individual Animals with Boxplots.





  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means116.5   n 72.8   n
Median of the strain means105.1   n 63.75   n
SD of the strain means± 57.12 ± 30.012
Coefficient of variation (CV)0.4902 0.4123
Min–max range of strain means48.2   –   202.0   n 40.857   –   137.0   n
Mean sample size per strain43.5   mice 41.2   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 2138.97 2138.97 0.0282 0.8667
strain 6 269933.5463 44988.9244 0.5931 0.736
sex:strain 6 140946.0937 23491.0156 0.3097 0.932
Residuals 661 50139372.6285 75853.8164


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
A/J f 54.89 44.577   9 14.859 0.8121 -1.08
A/J m 40.857 44.33   7 16.755 1.085 -1.06
C57BL/6J f 195.8 175.2   12 50.57 0.8945 9.0, 643.0 1.39
C57BL/6J m 61.0 44.972   13 12.473 0.7372 3.0, 169.0 -0.39
CAST/EiJ f 202.0 0.0   1   0.0 0.0 202.0, 202.0 1.5
CAST/EiJ m 65.5 53.03   2   37.5 0.8097 28.0, 103.0 -0.24
J:DO f 125.5 204.4   295 11.904 1.6288 0.16
J:DO m 137.0 364.7   281 21.757 2.6626 2.14
NOD/ShiLtJ f 106.7 105.7   11 31.883 0.9908 4.0, 351.0 -0.17
NOD/ShiLtJ m 62.0 44.371   6 18.114 0.7157 10.0, 114.0 -0.36
NZO/HlLtJ f 48.2 37.273   10 11.787 0.7733 7.0, 103.0 -1.2
NZO/HlLtJ m 52.8 34.628   10 10.95 0.6558 11.0, 127.0 -0.67
PWK/PhJ f 103.4 75.63   7 28.585 0.7312 29.0, 253.0 -0.23
PWK/PhJ m 93.83 52.5   6 21.433 0.5595 15.0, 144.0 0.7
WSB/EiJ f 95.67 82.95   3 47.893 0.8671 3.0, 163.0 -0.36
WSB/EiJ m 69.4 51.83   5 23.181 0.7469 18.0, 129.0 -0.11


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J f 54.8888888889 91.8052385228 235.1539248359 -125.3761470581
A/J m 40.8571428571 104.0973557932 245.2584807982 -163.5441950839
C57BL/6J f 195.8333333333 79.5056687612 351.9474338775 39.7192327891
C57BL/6J m 61.0 76.3865757346 210.9895762185 -88.9895762185
J:DO f 125.5186440678 16.035322914 157.004952562 94.0323355736
J:DO m 136.9715302491 16.4299241341 169.232661665 104.7103988333
NOD/ShiLtJ f 106.7272727273 83.0409627188 269.7831328335 -56.3285873789
NOD/ShiLtJ m 62.0 112.4379950476 282.7786782673 -158.7786782673
NZO/HlLtJ f 48.2 87.0940964601 219.2144288254 -122.8144288254
NZO/HlLtJ m 52.8 87.0940964601 223.8144288254 -118.2144288254
PWK/PhJ f 103.4285714286 104.0973557932 307.8299093697 -100.9727665125
PWK/PhJ m 93.8333333333 112.4379950476 314.6120116006 -126.945344934
WSB/EiJ f 95.6666666667 159.0113375224 407.8948677551 -216.5615344217
WSB/EiJ m 69.4 123.1696524165 311.2509246063 -172.4509246063


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
A/J both 47.873015873 69.3982371955 184.1405745004 -88.3945427544
C57BL/6J both 128.4166666667 55.1272625786 236.6623194234 20.1710139099
J:DO both 131.2450871585 11.479045997 153.7848754384 108.7052988785
NOD/ShiLtJ both 84.3636363636 69.8893844221 221.5955917279 -52.8683190007
NZO/HlLtJ both 50.5 61.5848262082 171.4254623032 -70.4254623032
PWK/PhJ both 98.630952381 76.6135794319 249.0662638354 -51.8043590735
WSB/EiJ both 82.5333333333 100.5676000721 280.0037863686 -114.937119702




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA