Project measure / variable:   CSNA03   extinction_active_do_s6

ID, description, units MPD:110276   extinction_active_do_s6   extinction, active lever presses (intravenous self administration), DO   [n]  session 6  
cocaine study
Data set, strains CSNA03   DO population w/par   8 strains     sex: both     age:
Procedure operant conditioning chamber
Ontology mappings

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Plot Options Bins number: (min: 10, max: 40)


Distribution of Individual Animals with Boxplots.





  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested8 strains8 strains
Mean of the strain means80.31   n 58.14   n
Median of the strain means76.84   n 45.091   n
SD of the strain means± 54.77 ± 52.67
Coefficient of variation (CV)0.682 0.9059
Min–max range of strain means13.714   –   170.7   n 21.286   –   185.4   n
Mean sample size per strain26.2   mice 23.5   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 36839.9561 36839.9561 0.2779 0.5984
strain 6 927134.1095 154522.3516 1.1655 0.324
sex:strain 6 167811.7695 27968.6282 0.211 0.9733
Residuals 381 50513185.4408 132580.5392


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
Select table page:
Strain Sex Mean SD N mice SEM CV Min, Max Z score
A/J f 13.714 15.671   7 5.923 1.1427 -1.22
A/J m 21.286 27.903   7 10.546 1.3109 -0.7
C57BL/6J f 170.7 250.4   10 79.18 1.4668 15.0, 813.0 1.65
C57BL/6J m 42.182 33.34   11 10.052 0.7904 7.0, 108.0 -0.3
CAST/EiJ f 77.0 0.0   1   0.0 0.0 77.0, 77.0 -0.06
CAST/EiJ m 48.0 18.385   2   13.0 0.383 35.0, 61.0 -0.19
J:DO f 144.9 247.5   164 19.33 1.7084 2.0, 2164.0 1.18
J:DO m 185.4 534.9   140 45.204 2.8845 2.42
NOD/ShiLtJ f 77.2 105.7   10 33.419 1.3689 5.0, 320.0 -0.06
NOD/ShiLtJ m 38.0 23.264   6 9.4974 0.6122 9.0, 68.0 -0.38
NZO/HlLtJ f 17.5 18.447   10 5.8333 1.0541 -1.15
NZO/HlLtJ m 26.1 18.592   10 5.8792 0.7123 3.0, 69.0 -0.61
PWK/PhJ f 64.8 101.1   5 45.217 1.5603 1.0, 244.0 -0.28
PWK/PhJ m 52.14 36.613   7 13.838 0.7022 11.0, 96.0 -0.11
WSB/EiJ f 76.67 81.27   3 46.92 1.06 16.0, 169.0 -0.07
WSB/EiJ m 52.0 41.201   5 18.426 0.7923 3.0, 84.0 -0.12


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J f 13.7142857143 137.6229524123 284.3098983736 -256.8813269451
A/J m 21.2857142857 137.6229524123 291.8813269451 -249.3098983736
C57BL/6J f 170.7 115.143623017 397.0965324676 -55.6965324676
C57BL/6J m 42.1818181818 109.7851369369 258.0424422246 -173.678805861
J:DO f 144.8963414634 28.4326910798 200.8009803877 88.9917025391
J:DO m 185.4285714286 30.7734276858 245.9355898605 124.9215529966
NOD/ShiLtJ f 77.2 115.143623017 303.5965324676 -149.1965324676
NOD/ShiLtJ m 38.0 148.6497781223 330.2766666287 -254.2766666287
NZO/HlLtJ f 17.5 115.143623017 243.8965324676 -208.8965324676
NZO/HlLtJ m 26.1 115.143623017 252.4965324676 -200.2965324676
PWK/PhJ f 64.8 162.8376732914 384.9730466899 -255.3730466899
PWK/PhJ m 52.1428571429 137.6229524123 322.7384698022 -218.4527555165
WSB/EiJ f 76.6666666667 210.2225322643 490.0082925782 -336.6749592448
WSB/EiJ m 52.0 162.8376732914 372.1730466899 -268.1730466899


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
A/J both 17.5 97.3141228977 208.8399926708 -173.8399926708
C57BL/6J both 106.4409090909 79.5468890242 262.8467904745 -49.9649722927
J:DO both 165.162456446 20.9488769005 206.3523457781 123.9725671138
NOD/ShiLtJ both 57.6 94.014374509 242.4519946937 -127.2519946937
NZO/HlLtJ both 21.8 81.4188366457 181.886523345 -138.286523345
PWK/PhJ both 58.4714285714 106.6022805498 268.0738888487 -151.1310317059
WSB/EiJ both 64.3333333333 132.9564034887 325.7535312609 -197.0868645942




GWAS analysis not available: Strain panel must be either Inbred, HMDP, BXD, BXH, CXB, or AXB/BXA