Project measure / variable:   CSNA03   extinction_inactive_in_s5

ID, description, units MPD:110211   extinction_inactive_in_s5   extinction, inactive lever presses (intravenous self administration), founders   [n]  session 5  
cocaine study
Data set, strains CSNA03   inbred w/CC8   7 strains     sex: both     age:
Procedure operant conditioning chamber
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  STRAIN COMPARISON PLOT
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CSNA03 - extinction, inactive lever presses (intravenous self administration), founders session 5



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested7 strains7 strains
Mean of the strain means27.292   n 25.743   n
Median of the strain means23.333   n 21.2   n
SD of the strain means± 13.721 ± 27.428
Coefficient of variation (CV)0.5027 1.0655
Min–max range of strain means7.0   –   41.1   n 5.4   –   85.43   n
Mean sample size per strain6.7   mice 6.7   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 63.6639 63.6639 0.0151 0.9026
strain 5 18732.4304 3746.4861 0.8872 0.4938
sex:strain 5 22458.0596 4491.6119 1.0637 0.3869
Residuals 79 333592.7472 4222.693


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
A/J f 20.286 28.182   7 10.652 1.3893 2.0, 76.0 -0.51
A/J m 85.43 190.9   7 72.15 2.2344 2.18
C57BL/6J f 40.727 77.16   11 23.265 1.8946 0.98
C57BL/6J m 9.4545 10.367   11 3.1257 1.0965 2.0, 37.0 -0.59
CAST/EiJ f 41.0 0.0   1   0.0 0.0 41.0, 41.0 1.0
CAST/EiJ m 21.5 30.406   2   21.5 1.4142 -0.15
NOD/ShiLtJ f 41.1 61.34   10 19.398 1.4925 1.01
NOD/ShiLtJ m 21.2 21.04   5 9.4096 0.9925 2.0, 53.0 -0.17
NZO/HlLtJ f 7.0 6.549   10 2.071 0.9356 -1.48
NZO/HlLtJ m 10.5 8.1275   10 2.5701 0.774 1.0, 25.0 -0.56
PWK/PhJ f 17.6 13.903   5 6.2177 0.79 4.0, 33.0 -0.71
PWK/PhJ m 26.714 41.696   7 15.76 1.5608 0.04
WSB/EiJ f 23.333 28.729   3 16.586 1.2312 2.0, 56.0 -0.29
WSB/EiJ m 5.4 5.7706   5 2.5807 1.0686 -0.74


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J f 20.2857142857 24.5609824209 69.1731269088 -28.6016983374
A/J m 85.4285714286 24.5609824209 134.3159840517 36.5411588054
C57BL/6J f 40.7272727273 19.5928860057 79.7259367963 1.7286086582
C57BL/6J m 9.4545454545 19.5928860057 48.4532095236 -29.5441186145
NOD/ShiLtJ f 41.1 20.549192204 82.0021439424 0.1978560576
NOD/ShiLtJ m 21.2 29.0609463107 79.0443666935 -36.6443666935
NZO/HlLtJ f 7.0 20.549192204 47.9021439424 -33.9021439424
NZO/HlLtJ m 10.5 20.549192204 51.4021439424 -30.4021439424
PWK/PhJ f 17.6 29.0609463107 75.4443666935 -40.2443666935
PWK/PhJ m 26.7142857143 24.5609824209 75.6016983374 -22.1731269088
WSB/EiJ f 23.3333333333 37.5175203621 98.0100896253 -51.3434229587
WSB/EiJ m 5.4 29.0609463107 63.2443666935 -52.4443666935


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
A/J both 52.8571428571 17.3672372224 87.4257638376 18.2885218767
C57BL/6J both 25.0909090909 13.8542625576 52.6671289114 -2.4853107295
NOD/ShiLtJ both 31.15 17.7961224759 66.5722957234 -4.2722957234
NZO/HlLtJ both 8.75 14.5304731553 37.6721833468 -20.1721833468
PWK/PhJ both 22.1571428571 19.0248551765 60.0251698429 -15.7108841286
WSB/EiJ both 14.3666666667 23.7281633012 61.5963942979 -32.8630609645




  GWAS USING LINEAR MIXED MODELS