Project measure / variable:   CSNA03   extinction_active_in_s6

ID, description, units MPD:110203   extinction_active_in_s6   extinction, active lever presses (intravenous self administration), founders   [n]  session 6  
cocaine study
Data set, strains CSNA03   inbred w/CC8   7 strains     sex: both     age:
Procedure operant conditioning chamber
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  STRAIN COMPARISON PLOT
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CSNA03 - extinction, active lever presses (intravenous self administration), founders session 6



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested7 strains7 strains
Mean of the strain means71.08   n 39.958   n
Median of the strain means76.67   n 42.182   n
SD of the strain means± 52.01 ± 12.299
Coefficient of variation (CV)0.7316 0.3078
Min–max range of strain means13.714   –   170.7   n 21.286   –   52.14   n
Mean sample size per strain6.6   mice 6.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 29282.1806 29282.1806 3.0445 0.0849
strain 5 94088.8121 18817.7624 1.9565 0.0943
sex:strain 5 63249.6614 12649.9323 1.3152 0.2662
Residuals 79 759833.9173 9618.1509


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
A/J f 13.714 15.671   7 5.923 1.1427 -1.1
A/J m 21.286 27.903   7 10.546 1.3109 -1.52
C57BL/6J f 170.7 250.4   10 79.18 1.4668 15.0, 813.0 1.92
C57BL/6J m 42.182 33.34   11 10.052 0.7904 7.0, 108.0 0.18
CAST/EiJ f 77.0 0.0   1   0.0 0.0 77.0, 77.0 0.11
CAST/EiJ m 48.0 18.385   2   13.0 0.383 35.0, 61.0 0.65
NOD/ShiLtJ f 77.2 105.7   10 33.419 1.3689 5.0, 320.0 0.12
NOD/ShiLtJ m 38.0 23.264   6 9.4974 0.6122 9.0, 68.0 -0.16
NZO/HlLtJ f 17.5 18.447   10 5.8333 1.0541 -1.03
NZO/HlLtJ m 26.1 18.592   10 5.8792 0.7123 3.0, 69.0 -1.13
PWK/PhJ f 64.8 101.1   5 45.217 1.5603 1.0, 244.0 -0.12
PWK/PhJ m 52.14 36.613   7 13.838 0.7022 11.0, 96.0 0.99
WSB/EiJ f 76.67 81.27   3 46.92 1.06 16.0, 169.0 0.11
WSB/EiJ m 52.0 41.201   5 18.426 0.7923 3.0, 84.0 0.98


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J f 13.7142857143 37.0677966745 87.4958893978 -60.0673179692
A/J m 21.2857142857 37.0677966745 95.0673179692 -52.4958893978
C57BL/6J f 170.7 31.0131437492 232.4301184955 108.9698815045
C57BL/6J m 42.1818181818 29.5698723398 101.039176797 -16.6755404334
NOD/ShiLtJ f 77.2 31.0131437492 138.9301184955 15.4698815045
NOD/ShiLtJ m 38.0 40.0377964181 117.6932402976 -41.6932402976
NZO/HlLtJ f 17.5 31.0131437492 79.2301184955 -44.2301184955
NZO/HlLtJ m 26.1 31.0131437492 87.8301184955 -35.6301184955
PWK/PhJ f 64.8 43.859208502 152.0995707833 -22.4995707833
PWK/PhJ m 52.1428571429 37.0677966745 125.9244608263 -21.6387465406
WSB/EiJ f 76.6666666667 56.621994702 189.3699279249 -36.0365945916
WSB/EiJ m 52.0 43.859208502 139.2995707833 -35.2995707833


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
A/J both 17.5 26.2108903922 69.6714722914 -34.6714722914
C57BL/6J both 106.4409090909 21.4254080206 149.0871169898 63.794701192
NOD/ShiLtJ both 57.6 25.3221258351 108.0024306919 7.1975693081
NZO/HlLtJ both 21.8 21.929604251 65.4497853916 -21.8497853916
PWK/PhJ both 58.4714285714 28.7125918402 115.6224130359 1.3204441069
WSB/EiJ both 64.3333333333 35.8108937841 135.6131343944 -6.9464677277




  GWAS USING LINEAR MIXED MODELS