Project measure / variable:   CSNA03   extinction_active_in_s1

ID, description, units MPD:110198   extinction_active_in_s1   extinction, active lever presses (intravenous self administration), founders   [n]  session 1  
cocaine study
Data set, strains CSNA03   inbred w/CC8   7 strains     sex: both     age:
Procedure operant conditioning chamber
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  STRAIN COMPARISON PLOT
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CSNA03 - extinction, active lever presses (intravenous self administration), founders session 1



  MEASURE SUMMARY
Measure Summary FemaleMale
Number of strains tested7 strains7 strains
Mean of the strain means108.9   n 90.45   n
Median of the strain means108.0   n 79.0   n
SD of the strain means± 51.68 ± 44.62
Coefficient of variation (CV)0.4744 0.4933
Min–max range of strain means55.44   –   198.2   n 35.4   –   149.9   n
Mean sample size per strain7.1   mice 6.9   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
sex 1 15915.5227 15915.5227 1.6235 0.2062
strain 5 178016.1762 35603.2352 3.6318 0.0051
sex:strain 5 43703.2467 8740.6493 0.8916 0.4907
Residuals 83 813666.2754 9803.2081


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
A/J f 55.44 34.431   9 11.477 0.621 7.0, 99.0 -1.04
A/J m 67.86 44.592   7 16.854 0.6572 20.0, 155.0 -0.51
C57BL/6J f 198.2 114.6   12 33.082 0.578 8.0, 476.0 1.73
C57BL/6J m 105.3 58.97   12 17.022 0.5598 18.0, 208.0 0.33
CAST/EiJ f 108.0 0.0   1   0.0 0.0 108.0, 108.0 -0.02
CAST/EiJ m 79.0 9.8995   2   7.0 0.1253 72.0, 86.0 -0.26
NOD/ShiLtJ f 126.3 205.2   10 64.9 1.625 9.0, 700.0 0.34
NOD/ShiLtJ m 144.8 162.4   6 66.3 1.1213 4.0, 459.0 1.22
NZO/HlLtJ f 72.6 56.85   10 17.977 0.783 4.0, 170.0 -0.7
NZO/HlLtJ m 50.89 33.714   9 11.238 0.6625 16.0, 118.0 -0.89
PWK/PhJ f 142.5 81.12   6 33.117 0.5693 52.0, 237.0 0.65
PWK/PhJ m 149.9 63.68   7 24.068 0.4249 70.0, 229.0 1.33
WSB/EiJ f 59.5 17.678   2   12.5 0.2971 47.0, 72.0 -0.96
WSB/EiJ m 35.4 26.754   5 11.965 0.7558 8.0, 78.0 -1.23


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
A/J f 55.4444444444 33.0037171935 121.0875105386 -10.1986216498
A/J m 67.8571428571 37.4226977292 142.2893835061 -6.5750977919
C57BL/6J f 198.25 28.5820575089 255.0985628199 141.4014371801
C57BL/6J m 105.3333333333 28.5820575089 162.1818961532 48.4847705135
NOD/ShiLtJ f 126.3 31.3100752751 188.5744804364 64.0255195636
NOD/ShiLtJ m 144.8333333333 40.4211333696 225.2293418746 64.437324792
NZO/HlLtJ f 72.6 31.3100752751 134.8744804364 10.3255195636
NZO/HlLtJ m 50.8888888889 33.0037171935 116.5319549831 -14.7541772053
PWK/PhJ f 142.5 40.4211333696 222.8960085413 62.1039914587
PWK/PhJ m 149.8571428571 37.4226977292 224.2893835061 75.4249022081
WSB/EiJ f 59.5 70.0114566957 198.7499715192 -79.7499715192
WSB/EiJ m 35.4 44.2791330929 123.4694148229 -52.6694148229


  LEAST SQUARES MEANS (MODEL-ADJUSTED), SEXES COMBINED
Strain Sex Mean SEM UpperCL LowerCL
A/J both 61.6507936508 24.9484651528 111.2722874168 12.0292998848
C57BL/6J both 151.7916666667 20.2105666848 191.9896709373 111.593662396
NOD/ShiLtJ both 135.5666666667 25.5645694107 186.413567022 84.7197663113
NZO/HlLtJ both 61.7444444444 22.7462423398 106.9858056084 16.5030832805
PWK/PhJ both 146.1785714286 27.5423597764 200.959217275 91.3979255822
WSB/EiJ both 47.45 41.4193363543 129.8313941302 -34.9313941302




  GWAS USING LINEAR MIXED MODELS