Project measure / variable:   Mooney2   context_12

ID, description, units MPD:110086   context_12   percent freezing during a context testing trial   [%]  12 mg/kg/day  
nicotine study
Data set, strains Mooney2   inbred   21 strains     sex: m     age:
Procedure fear conditioning test
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  STRAIN COMPARISON PLOT
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Mooney2 - percent freezing during a context testing trial 12 mg/kg/day



  MEASURE SUMMARY
Measure Summary Male
Number of strains tested21 strains
Mean of the strain means40.938   %
Median of the strain means34.008   %
SD of the strain means± 22.7
Coefficient of variation (CV)0.5545
Min–max range of strain means5.4218   –   80.39   %
Mean sample size per strain9.8   mice


  ANOVA, Q-Q NORMALITY ASSESSMENT
ANOVA summary      
FactorDFSum of squaresMean sum of squaresF valuep value (Pr>F)
strain 20 102539.4514 5126.9726 28.5951 < 0.0001
Residuals 184 32990.3324 179.2953


Q-Q normality assessment based on residuals

  


  STRAIN MEANS (UNADJUSTED)
  
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Strain Sex Mean SD N mice SEM CV Min, Max Z score
129S1/SvImJ m 70.4 10.697   10 3.3828 0.1519 51.8, 82.71 1.3
129S2/SvPasCrl m 69.44 12.04   10 3.8074 0.1734 53.24, 89.58 1.26
129S4/SvJaeJ m 59.38 14.227   10 4.4989 0.2396 31.84, 78.71 0.81
129S8/SvEvNimrJ m 62.52 17.972   9 5.9906 0.2875 39.46, 89.3 0.95
A/J m 62.49 14.539   10 4.5976 0.2327 41.02, 89.84 0.95
AKR/J m 29.73 15.566   10 4.9222 0.5236 10.01, 56.19 -0.49
BALB/cJ m 26.682 17.718   10 5.6029 0.664 6.32, 56.11 -0.63
BTBR T+ Itpr3tf/J m 10.212 4.4182   10 1.3972 0.4327 3.91, 17.52 -1.35
C3H/HeJ m 28.163 9.2201   10 2.9157 0.3274 14.0, 40.61 -0.56
C57BL/6J m 52.34 10.082   8 3.5644 0.1926 40.64, 69.35 0.5
CBA/J m 29.378 20.644   9 6.8814 0.7027 7.77, 69.13 -0.51
DBA/1J m 39.821 19.366   10 6.1241 0.4863 15.17, 63.18 -0.05
DBA/2J m 52.1 13.687   10 4.3282 0.2627 30.92, 76.96 0.49
FVB/NJ m 10.759 7.3026   10 2.3093 0.6787 3.66, 26.48 -1.33
LP/J m 67.56 11.244   10 3.5558 0.1664 52.69, 81.53 1.17
MA/MyJ m 20.367 15.07   9 5.0234 0.7399 2.21, 44.36 -0.91
NOD/ShiLtJ m 18.553 9.7036   9 3.2345 0.523 7.65, 37.36 -0.99
NZB/BlNJ m 34.008 14.11   10 4.4619 0.4149 17.93, 63.5 -0.31
SJL/J m 29.976 14.389   10 4.5501 0.48 13.14, 59.94 -0.48
SM/J m 80.39 8.34   10 2.6373 0.1037 70.02, 95.72 1.74
SWR/J m 5.4218 8.658   11 2.6105 1.5969 0.4, 30.13 -1.56


  LEAST SQUARES MEANS (MODEL-ADJUSTED)
Strain Sex Mean SEM UpperCL LowerCL
129S1/SvImJ m 70.402 4.234327397 78.7560761913 62.0479238087
129S2/SvPasCrl m 69.44 4.234327397 77.7940761913 61.0859238087
129S4/SvJaeJ m 59.376 4.234327397 67.7300761913 51.0219238087
129S8/SvEvNimrJ m 62.5166666667 4.4633729778 71.3226361704 53.710697163
A/J m 62.488 4.234327397 70.8420761913 54.1339238087
AKR/J m 29.73 4.234327397 38.0840761913 21.3759238087
BALB/cJ m 26.682 4.234327397 35.0360761913 18.3279238087
BTBR T+ Itpr3tf/J m 10.212 4.234327397 18.5660761913 1.8579238087
C3H/HeJ m 28.163 4.234327397 36.5170761913 19.8089238087
C57BL/6J m 52.34 4.7341219493 61.6801411265 42.9998588735
CBA/J m 29.3777777778 4.4633729778 38.1837472815 20.5718082741
DBA/1J m 39.821 4.234327397 48.1750761913 31.4669238087
DBA/2J m 52.1 4.234327397 60.4540761913 43.7459238087
FVB/NJ m 10.759 4.234327397 19.1130761913 2.4049238087
LP/J m 67.563 4.234327397 75.9170761913 59.2089238087
MA/MyJ m 20.3666666667 4.4633729778 29.1726361704 11.560697163
NOD/ShiLtJ m 18.5533333333 4.4633729778 27.359302837 9.7473638296
NZB/BlNJ m 34.008 4.234327397 42.3620761913 25.6539238087
SJL/J m 29.976 4.234327397 38.3300761913 21.6219238087
SM/J m 80.395 4.234327397 88.7490761913 72.0409238087
SWR/J m 5.4218181818 4.0372727637 13.3871172979 -2.5434809343




  GWAS USING LINEAR MIXED MODELS